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Biological and clinical significance of cancer stem cell plasticity

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Figure

Figure 1 Potential therapeutic targets of CSC plasticity. MET and EMT CSCs can readily transition back and forth between the two cell states.Potential targets for eliminating these populations include targeting each specific population with particular drugs such as Trastuzumab(MET CSCs) or Tocilizumab (EMT CSCs) or developing new drugs to target the pathways and ncRNAs involved in the transition between thepopulations.

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