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The anticancer immune response of anti-PD-1/PD-L1 and the genetic determinants of response to anti-PD-1/PD-L1 antibodies in cancer patients

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Academic year: 2020

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Figure

Figure 1: The role of PD-1/PD-L1 pathway in cell immune response. PD-1 functions to inhibit T cell activation not only by attenuating TCR signaling (SHP-1/2), but also by enhancing the expression of genes that impair T cell function
Table 1: Currently used anti-PD-1 and anti-PD-L1 antibodies
Table 2: Efficacy data of anti-PD-1 and anti-PD-L1 antibodies

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