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Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinoma

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Academic year: 2020

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Figure

Figure 1: Loss of FXR induced oncogenic behavior via Wnt/β-Catenin signaling in Huh7 cells
Figure 2: AF1 domain of FXR was required for the direct interaction between FXR and β-Catenin
Figure 3: FXR repressed β-Catenin mediated transcriptional activity. (A) FXR repressed β-Catenin mediated transcriptional activity in a dose dependent manner
Figure 4: FXR attenuates β-Catenin/TCF4 complex mediated cyclin D1 transcription. (A) FXR did not bind with TCF4
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