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The fitness cost of mis splicing is the main determinant of alternative splicing patterns

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Figure

Fig. 1 Introns and cryptic introns in(ASSV, n2), and to IR (n3). The IR rate is defined as n3/(n1 + n2 + n3), the ASSV rate is n2/(n1 + n2 + n3)
Table 1 Summary of AS rates in paramecia and human
Fig. 2 Impact of NMD on observed AS rates. AS events (IR or cryptic intron splicing) are classified into three groups according to their NMD-visibility: PTC-inducing events (i.e
Fig. 3 Relationship between AS rate and gene features: expression level, number of introns, or length of coding regions
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