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ARG098, a novel anti human Fas antibody, suppresses synovial hyperplasia and prevents cartilage destruction in a severe combined immunodeficient HuRAg mouse model

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Figure

Figure 1 ARG098 binding and cytotoxicity to rheumatoid arthritis (RA) synoviocytesARG098
Figure 2 Cytotoxic effect of ARG098 on RA synoviocytespreincubated with inflammatory cytokines
Figure 3 Effect of ARG098 on infiltrating lymphocytes isolated from the synovium of RA patients and peripheral blood mononuclearcells in lymphocytes isolated from RA patients
Figure 4 ARG098 cytotoxicity to human chondrocytescytometory. The white area is stained with human IgM and the black area is stained with ARG098
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