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(1)

DENTISTRY

(2)

(HOCl)

Hypochlorous Acid

atm plus

has a broad spectrum anti-microbial use

also known as

• electrolyzed water / electrolyzed reduced water

(ERW, EW)

• electrochemically activated water

(ECA)

• anolyte

(AEW, NEW, SAEW)

(3)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• No polar charge

• Low molecular weight

PERFECT structure to penetrate CELL WALLS

• HOCl is a WEAK ACID

• At a pH of 4 – 8.5 most available Chlorine is HOCl

NO RESIDUE after dissolving in water

• Solution stays active for 7 – 10 DAYS

(4)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• HOCl diffuse through cell membrane

• Without a polar charge it is not repelled

• OCl- (BLEACH) is unable to penetrate cell membrane due to negative charge

• Bleach can only clean on the EXTERIOR

• HOCl acts from INSIDE

hypochlorousacid.com/about

(5)

(HOCl) NATURE of Hypochlorous Acid

“Hypochlorous acid is LETHAL to every pathogen

it has been tested against but completely HARMLESS

to humans and other mammals.”

• Natural component of our own immune systems

• Fights against infection

• Reduces inflammation

• Bio-degradable in the environment

atm plus

organic, lethal, cost effective

(6)

phagocytosis

[ fag-uh-sahy-toh-sis ]

noun

Physiology. the ingestion of a smaller cell or cell fragment, a microorganism, or foreign particles by means of the local infolding of a cell's membrane and the protrusion of its cytoplasm around the fold until the material has been surrounded and engulfed by closure of the membrane and formation of a vacuole:

characteristic of amoebas and some types of white blood cells.

• Neutrophils (WHITE BLOOD CELLS) seek out pathogens

(VIRUSES AND BACTERIA) and destroy them using HOCl

• HOCl causes necrosis (RUPTURING OF THE CELL) and destroys the cell contents

• While disinfecting, HOCl is {OXIDISED} and consumed

• The only by-product is slightly salty water

(7)

EFFECTIVENESS OF HOCl

atm plus

80 – 100 times more effective than bleach

atm plus

disinfects and destroys:

✓ VIRUSES

✓ BACTERIA

✓ MOULDS

✓ FUNGI

✓ SPORES

✓ BIOFILMS

✓ INFECTION

✓ RESISTANCE/TOLERANCE

✓ PATHOGENS BENEATH BIOFILMS

✓ FERMENTATION IN STORAGE

defends against:

(8)

atm plus

80 – 100 times more effective than bleach

PROVEN EFFECTIVE AGAINST SARS-CoV-2

Michael S. Block, Brian G. Rowan, Hypochlorous Acid: A Review,

J Oral Maxillofac Surg, 10.1016/j.joms.2020.06.029

‘The surgeon needs to have an inexpensive, available, nontoxic, and practical disinfectant that is effective in sanitizing against the COVID-

19 (Coronavirus Disease 2019) virus.’

‘The results indicate that this material can be used with a high predictability for disinfecting against the COVID-19 (Coronavirus

Disease 2019) virus.’

Chan K-H, Sridhar S, Zhang RR, Chu H, Fung AY-F, Chan G, Chan JF-W,

To KK-W, Hung IF-N, Cheng VC-C, Yuen K-Y, Factors affecting stability and infectivity of SARS- CoV-2,

Journal of Hospital Infection,

https://doi.org/10.1016/j.jhin.2020.07.009.

The latest peer approved scientific papers conclusively show that HOCL effectively kills the SARS-Covid 2 virus. The papers

also compare HOCL to other disinfectants showing its comparative performance with other disinfectants such as

bleach.

(9)

atm plus

effective at 25PPM to 200PPM depending on use HOCl concentrated into a

6 gram

dissolvable tablet

the effervescent tablet

atm plus

1 tablet = 12.5l of disinfectant

consistent solution at 100PPM every time

easy STORAGE low TRANSPORT COSTS

active for 7 – 10 DAYS after dissolving then returns to pure water

1 year SHELF LIFE in tablet form

(10)

to name a few…

USES OF atm plus

atm plus

100% organic, bio-degradable, MRL FREE

• DISINFECTING any and all surfaces

• AGRICULTURAL

• LIVESTOCK

• MEDICINAL / DENTISTRY

fresh fruit / veg preparation hydroponics / irrigation pesticidal treatment

control / reduction of disease

improves digestion / feed conversion ratios increase livestock yields

mouthwash / wound care waterline disinfection scrubbing in

(11)

to name a few…

USES OF atm plus

atm plus

safer exposure to humans than regular disinfectant

• HORTICULTURE

• WATER TREATMENT

• FACILITIES

• TRANSPORT

increase shelf life

reduces rotting / infection

shopping centres accommodation office buildings

airlines / airports public transport

shipping / cruiseliners

(12)

atm plus:

atm plus

gentle, effective, safe – NO PPE NECESSARY

GENERAL USE

atm plus CAN BE USED TO CLEAN AND SANITIZE:

• Floors and walls

• Reception areas

• Staff and patients hands, clothes and shoes

• Food contact surfaces

‘As a Disinfectant/Sterilant, HOCl has greater killing power than Chlorine, Chlorinated Water, Chlorine Dioxide, Sodium Hypochlorite, Hydrogen Peroxide and Ozone’

(13)

atm plus:

atm plus

reduces overall bacterial spread

DENTISTRY

• DENTAL UNIT WATERLINE DISINFECTION

• AS A MOUTHWASH

• ENVIRONMENT / EQUIPMENT DISINFECTION

• AS ANTIPLAQUE AGENT

• COLD FOGGING AGAINST VIRAL AIR PARTICLES

Hypochlorous acid is NON-Cytotoxic so it won’t harm human cells

(14)

atm plus:

atm plus

recommended use at 100 -

200PPM

DESTRUCTION OF BIOFILM AND SCALE IN WATER LINES

before treatment after treatment

DENTISTRY

(15)

atm plus:

atm plus

recommended use at 100 -

200PPM

DESTRUCTION OF BIOFILM AND SCALE IN DENTAL UNIT WATERLINES

DENTISTRY

Scanning electron microscope images show the efficacy of the disinfectant or disinfection procedure.

(a) The inner lumen wall of the cut section from the untreated dental waterlines (control tube) and the arrow indicates extensive mature microbial colonization with extensive organic matrix material.

(b) (b) The inner lumen of the cut section of treated dental unit waterline (sample a) and the arrow indicates the smooth tubing wall with no biofilms

Shajahan IF, Kandaswamy D, Srikanth P, Narayana LL, Selvarajan R. Dental unit waterlines disinfection using hypochlorous acid-based disinfectant. J Conserv Dent.

2016;19(4):347-350. doi:10.4103/0972-0707.186441

• 13 New dental units

• Biofilm allowed to grow for 10 DAYS

• 12 Units Treated, 1 Untreated

• The results are definitive

• Untreateddental unit waterlines showed a microbial colonization with continuous filamentous organic matrix

• There was no slime layer or bacterial cells seen in any of the 12 treateddental waterlines which mean that there was no evident of biofilm formation

(16)

atm plus:

atm plus

is non-mutagenic so it won’t damage human DNA

AS A MOUTHWASH / PLAQUE CONTROL AGENT:

The purpose of this study was to compare the preventive effects of the slightly acidic hypochlorous acid (HOCl) mouthwash and chlorhexidine (CHX) mouthwash as a chemical

plaque control agent for oral diseases.

DENTISTRY

Comparison of O’Leary index. X1: Oral care with 0.9% saline solution (1 min/15ml); X2: Oral care with 0.005% CHX (1min/15 ml); X3: Oral care with

slightly acidic HOCl water (1 min/15ml). Biomedical Research 2018; 29 (8): 1718-1723

(17)

atm plus:

atm plus

“the form of free available chlorine that has the highest bactericidal activity against a broad range of microorganisms” (US FDA, 2015)

COLD FOGGING: TO DEFEND AGAINST AEROSOLS

‘Some disinfectants work by disrupting intermolecular interactions. They can’t differentiate between human and microbial cells. HOCl {atm plus} breaks down to prevent this’

• It carries no electrical charge and is not repelled by germs

• 100% safe, non-irritant, non-corrosive

• Use with ultra-low volume fogging machines o Mist over chair and all areas

o Will dry within a minute

o Can be used between each patient

DENTISTRY

(18)

FOOD AND BEVERAGE

FOCUS

(19)

(HOCl)

Hypochlorous Acid

atm plus

has a broad spectrum anti-microbial use

also known as

• electrolyzed water / electrolyzed reduced water

(ERW, EW)

• electrochemically activated water

(ECA)

• anolyte

(AEW, NEW, SAEW)

(20)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• No polar charge

• Low molecular weight

PERFECT structure to penetrate CELL WALLS

• HOCl is a WEAK ACID

• At a pH of 4 – 8.5 most available Chlorine is HOCl

NO RESIDUE after dissolving in water

• Solution stays active for 7 – 10 DAYS

(21)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• HOCl diffuse through cell membrane

• Without a polar charge it is not repelled

• OCl- (BLEACH) is unable to penetrate cell membrane due to negative charge

• Bleach can only clean on the EXTERIOR

• HOCl acts from INSIDE

hypochlorousacid.com/about

(22)

(HOCl) NATURE of Hypochlorous Acid

“Hypochlorous acid is LETHAL to every pathogen

it has been tested against but completely HARMLESS

to humans and other mammals.”

• Natural component of our own immune systems

• Fights against infection

• Reduces inflammation

• Bio-degradable in the environment

atm plus

organic, lethal, cost effective

(23)

phagocytosis

[ fag-uh-sahy-toh-sis ]

noun

Physiology. the ingestion of a smaller cell or cell fragment, a microorganism, or foreign particles by means of the local infolding of a cell's membrane and the protrusion of its cytoplasm around the fold until the material has been surrounded and engulfed by closure of the membrane and formation of a vacuole:

characteristic of amoebas and some types of white blood cells.

• Neutrophils (WHITE BLOOD CELLS) seek out pathogens

(VIRUSES AND BACTERIA) and destroy them using HOCl

• HOCl causes necrosis (RUPTURING OF THE CELL) and destroys the cell contents

• While disinfecting, HOCl is {OXIDISED} and consumed

• The only by-product is slightly salty water

(24)

EFFECTIVENESS OF HOCl

atm plus

80 – 100 times more effective than bleach

atm plus

disinfects and destroys:

✓ VIRUSES

✓ BACTERIA

✓ MOULDS

✓ FUNGI

✓ SPORES

✓ BIOFILMS

✓ INFECTION

✓ RESISTANCE/TOLERANCE

✓ PATHOGENS BENEATH BIOFILMS

✓ FERMENTATION IN STORAGE

defends against:

(25)

atm plus

80 – 100 times more effective than bleach

PROVEN EFFECTIVE AGAINST SARS-CoV-2

Michael S. Block, Brian G. Rowan, Hypochlorous Acid: A Review,

J Oral Maxillofac Surg, 10.1016/j.joms.2020.06.029

‘The surgeon needs to have an inexpensive, available, nontoxic, and practical disinfectant that is effective in sanitizing against the COVID-

19 (Coronavirus Disease 2019) virus.’

‘The results indicate that this material can be used with a high predictability for disinfecting against the COVID-19 (Coronavirus

Disease 2019) virus.’

Chan K-H, Sridhar S, Zhang RR, Chu H, Fung AY-F, Chan G, Chan JF-W,

To KK-W, Hung IF-N, Cheng VC-C, Yuen K-Y, Factors affecting stability and infectivity of SARS- CoV-2,

Journal of Hospital Infection,

https://doi.org/10.1016/j.jhin.2020.07.009.

The latest peer approved scientific papers conclusively show that HOCL effectively kills the SARS-Covid 2 virus. The papers

also compare HOCL to other disinfectants showing its comparative performance with other disinfectants such as

bleach.

(26)

atm plus

effective at 25PPM to 200PPM depending on use HOCl concentrated into a

6 gram

dissolvable tablet

the effervescent tablet

atm plus

1 tablet = 12.5l of disinfectant

consistent solution at 100PPM every time

easy STORAGE low TRANSPORT COSTS

active for 7 – 10 DAYS after dissolving then returns to pure water

1 year SHELF LIFE in tablet form

(27)

to name a few…

USES OF atm plus

atm plus

100% organic, bio-degradable, MRL FREE

• DISINFECTING any and all surfaces

• AGRICULTURAL

• LIVESTOCK

• MEDICINAL / DENTISTRY

fresh fruit / veg preparation hydroponics / irrigation pesticidal treatment

control / reduction of disease

improves digestion / feed conversion ratios increase livestock yields

mouthwash / wound care waterline disinfection scrubbing in

(28)

to name a few…

USES OF atm plus

atm plus

safer exposure to humans than regular disinfectant

• HORTICULTURE

• WATER TREATMENT

• FACILITIES

• TRANSPORT

increase shelf life

reduces rotting / infection

shopping centres accommodation office buildings

airlines / airports public transport

shipping / cruiseliners

(29)

atm plus:

atm plus

gentle, effective, safe – NO PPE NECESSARY

GENERAL USE

atm plus CAN BE USED TO CLEAN AND SANITIZE:

• Floors and walls

• Preparation areas

• Workers’ hands, clothes and shoes

• Food contact surfaces

‘As a Disinfectant/Sterilant, HOCl has greater killing power than Chlorine, Chlorinated Water, Chlorine Dioxide, Sodium Hypochlorite, Hydrogen Peroxide and Ozone’

(30)

atm plus:

atm plus

no DISCOLORATION after use on fresh produce

FOOD PROCESSING

Strawberries were treated by spraying HOCl {atm plus} on (1) and (2) and not spraying on Control (c)

TREATMENT AGAINST MOULDS AND FUNGI

Spraying of Strawberries post harvest 1 c

c 2

Strawberries 4 days after application Strawberries 14 days after application

Conclusion: fresh produce treated with HOCl stay FREE OF MOULDS for longer

(31)

atm plus:

atm plus

spray, wipe and dry: NO RINSE REQUIRED

• wash and rinse fruit and vegetables – NO RESIDUE ON PRODUCT

• disinfect and clean equipment – PREP AREAS, SORTING MACHINES, WASH BAYS

– PPE, BOOTS, TOOLS

• disinfect BINS, CRATES and STORAGE AREAS

‘.’

FOOD PROCESSING

(32)

atm plus:

atm plus

use at max 60PPM on fresh produce

Journal of Advances in Agriculture Vol 9 (2018) ISSN: 2349-0837

Lettuce was treated with tap water (c) anolyte without salts (1) and HOCl {atm plus} (2) for 15 minutes

Disinfection of leafy vegetables with activated waters

c 1 2 2 c

Lettuce after 24 hours of application Lettuce after 1 week of application

Conclusion: vegetables treated with HOCl stay FRESH (free of bacterial decay) for longer

FOOD PROCESSING

(33)

atm plus:

atm plus

No chlorine-induced phytotoxicity are observed on treated fruit

Carrots were dipped in HOCl {atm plus} (1) and Chlorinated water (2) for 5 or 20 minutes respectively

Anolyte vs chlorinated water as disinfecting dipping treatment

Conclusion: vegetables treated with HOCl stay FRESH (free of bacterial decay) for longer

Results after 16 days

Pears, apples, peaches and strawberries were dipped in HOCl {atm plus} and Chlorinated water

Results after 25 days

FOOD PROCESSING

(34)

atm plus:

atm plus

reduces overall bacterial spread

• POULTRY

• BEEF

• FISH

• PIGS

• GAME

‘We applied electrolyzed water (EW) directly to multi-strain cocktails ofListeria monocytogenes, E. coli O157:H7, and Salmonella sp. at 250 ppm free available chlorine (FAC) and achieved greater than 6-log reductions in 2 min’

FOOD PROCESSING

(35)

atm plus:

atm plus

should be used with an appropriate degreaser

ON CONTACT SURFACES

‘For fresh meats, a commonly used antimicrobial is organic acids like HOCl {atm plus}

• Reduces biofilm formation – with SUBMERSIVE treatments of 30 seconds

• Eliminates bacterial contamination

• Effectiveness is not dependent on surface type o Plastic cutting boards

o Wooden cutting boards o Steel preparation areas

FOOD PROCESSING

(36)

atm plus:

atm plus

recommended use at 100 -

200PPM

DESTRUCTION OF BIOFILM AND SCALE IN IRRIGATION SYSTEMS

before treatment

before treatment

after treatment

after treatment

FOOD PROCESSING

(37)

atm plus: COMPARING DISINFECTANTS

(38)
(39)

(HOCl)

Hypochlorous Acid

atm plus

has a broad spectrum anti-microbial use

also known as

• electrolyzed water / electrolyzed reduced water

(ERW, EW)

• electrochemically activated water

(ECA)

• anolyte

(AEW, NEW, SAEW)

(40)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• No polar charge

• Low molecular weight

PERFECT structure to penetrate CELL WALLS

• HOCl is a WEAK ACID

• At a pH of 4 – 8.5 most available Chlorine is HOCl

NO RESIDUE after dissolving in water

• Solution stays active for 7 – 10 DAYS

(41)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• HOCl diffuse through cell membrane

• Without a polar charge it is not repelled

• OCl- (BLEACH) is unable to penetrate cell membrane due to negative charge

• Bleach can only clean on the EXTERIOR

• HOCl acts from INSIDE

hypochlorousacid.com/about

(42)

(HOCl) NATURE of Hypochlorous Acid

“Hypochlorous acid is LETHAL to every pathogen

it has been tested against but completely HARMLESS

to humans and other mammals.”

• Natural component of our own immune systems

• Fights against infection

• Reduces inflammation

• Bio-degradable in the environment

atm plus

organic, lethal, cost effective

(43)

phagocytosis

[ fag-uh-sahy-toh-sis ]

noun

Physiology. the ingestion of a smaller cell or cell fragment, a microorganism, or foreign particles by means of the local infolding of a cell's membrane and the protrusion of its cytoplasm around the fold until the material has been surrounded and engulfed by closure of the membrane and formation of a vacuole:

characteristic of amoebas and some types of white blood cells.

• Neutrophils (WHITE BLOOD CELLS) seek out pathogens

(VIRUSES AND BACTERIA) and destroy them using HOCl

• HOCl causes necrosis (RUPTURING OF THE CELL) and destroys the cell contents

• While disinfecting, HOCl is {OXIDISED} and consumed

• The only by-product is slightly salty water

(44)

EFFECTIVENESS OF HOCl

atm plus

80 – 100 times more effective than bleach

atm plus

disinfects and destroys:

✓ VIRUSES

✓ BACTERIA

✓ MOULDS

✓ FUNGI

✓ SPORES

✓ BIOFILMS

✓ INFECTION

✓ RESISTANCE/TOLERANCE

✓ PATHOGENS BENEATH BIOFILMS

✓ FERMENTATION IN STORAGE

defends against:

(45)

atm plus

80 – 100 times more effective than bleach

PROVEN EFFECTIVE AGAINST SARS-CoV-2

Michael S. Block, Brian G. Rowan, Hypochlorous Acid: A Review,

J Oral Maxillofac Surg, 10.1016/j.joms.2020.06.029

‘The surgeon needs to have an inexpensive, available, nontoxic, and practical disinfectant that is effective in sanitizing against the COVID-

19 (Coronavirus Disease 2019) virus.’

‘The results indicate that this material can be used with a high predictability for disinfecting against the COVID-19 (Coronavirus

Disease 2019) virus.’

Chan K-H, Sridhar S, Zhang RR, Chu H, Fung AY-F, Chan G, Chan JF-W,

To KK-W, Hung IF-N, Cheng VC-C, Yuen K-Y, Factors affecting stability and infectivity of SARS- CoV-2,

Journal of Hospital Infection,

https://doi.org/10.1016/j.jhin.2020.07.009.

The latest peer approved scientific papers conclusively show that HOCL effectively kills the SARS-Covid 2 virus. The papers

also compare HOCL to other disinfectants showing its comparative performance with other disinfectants such as

bleach.

(46)

atm plus

effective at 25PPM to 200PPM depending on use HOCl concentrated into a

6 gram

dissolvable tablet

the effervescent tablet

atm plus

1 tablet = 12.5l of disinfectant

consistent solution at 100PPM every time

easy STORAGE low TRANSPORT COSTS

active for 7 – 10 DAYS after dissolving then returns to pure water

1 year SHELF LIFE in tablet form

(47)

to name a few…

USES OF atm plus

atm plus

100% organic, bio-degradable, MRL FREE

• DISINFECTING any and all surfaces

• AGRICULTURAL

• LIVESTOCK

• MEDICINAL / DENTISTRY

fresh fruit / veg preparation hydroponics / irrigation pesticidal treatment

control / reduction of disease

improves digestion / feed conversion ratios increase livestock yields

mouthwash / wound care waterline disinfection scrubbing in

(48)

to name a few…

USES OF atm plus

atm plus

safer exposure to humans than regular disinfectant

• HORTICULTURE

• WATER TREATMENT

• FACILITIES

• TRANSPORT

increase shelf life

reduces rotting / infection

shopping centres accommodation office buildings

airlines / airports public transport

shipping / cruiseliners

(49)

atm plus:

atm plus

gentle, effective, safe – NO PPE NECESSARY

GENERAL USE

atm plus CAN BE USED TO CLEAN AND SANITIZE:

• Floors and walls

• Preparation areas

• Workers’ hands, clothes and shoes

• Food contact surfaces

‘As a Disinfectant/Sterilant, HOCl has greater killing power than Chlorine, Chlorinated Water, Chlorine Dioxide, Sodium Hypochlorite, Hydrogen Peroxide and Ozone’

(50)

atm plus: COMPARING DISINFECTANTS

(51)

MEDICAL

(52)

(HOCl)

Hypochlorous Acid

atm plus

has a broad spectrum anti-microbial use

also known as

• electrolyzed water / electrolyzed reduced water

(ERW, EW)

• electrochemically activated water

(ECA)

• anolyte

(AEW, NEW, SAEW)

(53)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• No polar charge

• Low molecular weight

PERFECT structure to penetrate CELL WALLS

• HOCl is a WEAK ACID

• At a pH of 4 – 8.5 most available Chlorine is HOCl

NO RESIDUE after dissolving in water

• Solution stays active for 7 – 10 DAYS

(54)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• HOCl diffuse through cell membrane

• Without a polar charge it is not repelled

• OCl- (BLEACH) is unable to penetrate cell membrane due to negative charge

• Bleach can only clean on the EXTERIOR

• HOCl acts from INSIDE

hypochlorousacid.com/about

(55)

(HOCl) NATURE of Hypochlorous Acid

“Hypochlorous acid is LETHAL to every pathogen

it has been tested against but completely HARMLESS

to humans and other mammals.”

• Natural component of our own immune systems

• Fights against infection

• Reduces inflammation

• Bio-degradable in the environment

atm plus

organic, lethal, cost effective

(56)

phagocytosis

[ fag-uh-sahy-toh-sis ]

noun

Physiology. the ingestion of a smaller cell or cell fragment, a microorganism, or foreign particles by means of the local infolding of a cell's membrane and the protrusion of its cytoplasm around the fold until the material has been surrounded and engulfed by closure of the membrane and formation of a vacuole:

characteristic of amoebas and some types of white blood cells.

• Neutrophils (WHITE BLOOD CELLS) seek out pathogens

(VIRUSES AND BACTERIA) and destroy them using HOCl

• HOCl causes necrosis (RUPTURING OF THE CELL) and destroys the cell contents

• While disinfecting, HOCl is {OXIDISED} and consumed

• The only by-product is slightly salty water

(57)

EFFECTIVENESS OF HOCl

atm plus

80 – 100 times more effective than bleach

atm plus

disinfects and destroys:

✓ VIRUSES

✓ BACTERIA

✓ MOULDS

✓ FUNGI

✓ SPORES

✓ BIOFILMS

✓ INFECTION

✓ RESISTANCE/TOLERANCE

✓ PATHOGENS BENEATH BIOFILMS

✓ FERMENTATION IN STORAGE

defends against:

(58)

atm plus

80 – 100 times more effective than bleach

PROVEN EFFECTIVE AGAINST SARS-CoV-2

Michael S. Block, Brian G. Rowan, Hypochlorous Acid: A Review,

J Oral Maxillofac Surg, 10.1016/j.joms.2020.06.029

‘The surgeon needs to have an inexpensive, available, nontoxic, and practical disinfectant that is effective in sanitizing against the COVID-

19 (Coronavirus Disease 2019) virus.’

‘The results indicate that this material can be used with a high predictability for disinfecting against the COVID-19 (Coronavirus

Disease 2019) virus.’

Chan K-H, Sridhar S, Zhang RR, Chu H, Fung AY-F, Chan G, Chan JF-W,

To KK-W, Hung IF-N, Cheng VC-C, Yuen K-Y, Factors affecting stability and infectivity of SARS- CoV-2,

Journal of Hospital Infection,

https://doi.org/10.1016/j.jhin.2020.07.009.

The latest peer approved scientific papers conclusively show that HOCL effectively kills the SARS-Covid 2 virus. The papers

also compare HOCL to other disinfectants showing its comparative performance with other disinfectants such as

bleach.

(59)

atm plus

effective at 25PPM to 200PPM depending on use HOCl concentrated into a

6 gram

dissolvable tablet

the effervescent tablet

atm plus

1 tablet = 12.5l of disinfectant

consistent solution at 100PPM every time

easy STORAGE low TRANSPORT COSTS

active for 7 – 10 DAYS after dissolving then returns to pure water

1 year SHELF LIFE in tablet form

(60)

to name a few…

USES OF atm plus

atm plus

100% organic, bio-degradable, MRL FREE

• DISINFECTING any and all surfaces

• AGRICULTURAL

• LIVESTOCK

• MEDICINAL / DENTISTRY

fresh fruit / veg preparation hydroponics / irrigation pesticidal treatment

control / reduction of disease

improves digestion / feed conversion ratios increase livestock yields

mouthwash / wound care waterline disinfection scrubbing in

(61)

to name a few…

USES OF atm plus

atm plus

safer exposure to humans than regular disinfectant

• HORTICULTURE

• WATER TREATMENT

• FACILITIES

• TRANSPORT

increase shelf life

reduces rotting / infection

shopping centres accommodation office buildings

airlines / airports public transport

shipping / cruiseliners

(62)

atm plus: COMPARING DISINFECTANTS

(63)

atm plus:

atm plus

gentle, effective, safe – NO PPE NECESSARY

GENERAL USE

atm plus CAN BE USED TO CLEAN AND SANITIZE:

• Reception areas

• Administrative offices

• Mortuary

• Equipment

• Staff and patients hands, clothes and shoes

‘As a Disinfectant/Sterilant, HOCl has greater killing power than Chlorine, Chlorinated Water, Chlorine Dioxide, Sodium Hypochlorite, Hydrogen Peroxide and Ozone’

(64)

atm plus:

atm plus

reduces overall bacterial spread

MEDICAL

• DENTAL

• WARDS

• RADIOLOGY

• EMERGENCY SERVICE

Hypochlorous acid is NON-Cytotoxic so it won’t harm human cells

(65)

atm plus:

atm plus

reduces overall bacterial spread

MEDICAL: DENTAL

• DENTAL UNIT WATERLINE DISINFECTION

• AS A MOUTHWASH

• ENVIRONMENT / EQUIPMENT DISINFECTION

• AS ANTIPLAQUE AGENT

• COLD FOGGING AGAINST VIRAL AIR PARTICLES

Hypochlorous acid is NON-Cytotoxic so it won’t harm human cells

(66)

atm plus:

atm plus

recommended use at 100 -

200PPM

DESTRUCTION OF BIOFILM AND SCALE IN WATER LINES

before treatment after treatment

MEDICAL

(67)

atm plus:

atm plus

recommended use at 100 -

200PPM

DESTRUCTION OF BIOFILM AND SCALE IN DENTAL UNIT WATERLINES

Scanning electron microscope images show the efficacy of the disinfectant or disinfection procedure.

(a) The inner lumen wall of the cut section from the untreated dental waterlines (control tube) and the arrow indicates extensive mature microbial colonization with extensive organic matrix material.

(b) (b) The inner lumen of the cut section of treated dental unit waterline (sample a) and the arrow indicates the smooth tubing wall with no biofilms

Shajahan IF, Kandaswamy D, Srikanth P, Narayana LL, Selvarajan R. Dental unit waterlines disinfection using hypochlorous acid-based disinfectant. J Conserv Dent.

2016;19(4):347-350. doi:10.4103/0972-0707.186441

• 13 New dental units

• Biofilm allowed to grow for 10 DAYS

• 12 Units Treated, 1 Untreated

• The results are definitive

• Untreateddental unit waterlines showed a microbial colonization with continuous filamentous organic matrix

• There was no slime layer or bacterial cells seen in any of the 12 treateddental waterlines which mean that there was no evident of biofilm formation

MEDICAL: DENTAL

(68)

atm plus:

atm plus

“the form of free available chlorine that has the highest bactericidal activity against a broad range of microorganisms” (US FDA, 2015)

COLD FOGGING: TO DEFEND AGAINST AEROSOLS

‘Some disinfectants work by disrupting intermolecular interactions. They can’t differentiate between human and microbial cells. HOCl {atm plus} breaks down to prevent this’

• It carries no electrical charge and is not repelled by germs

• 100% safe, non-irritant, non-corrosive

• Use with ultra-low volume fogging machines o Mist over all areas

o Will dry within a minute

o Can be used between each patient

MEDICAL

(69)

atm plus:

atm plus

Biocide aerosolization proved to be efficient and safe in all applied way

COLD FOGGING: TO DEFEND AGAINST AEROSOLS

• Hospitals are facing increasingly resistant strains of micro-organisms

• Hard to properly disinfect electronic equipment like

• CT and MRI scanners

MEDICAL: RADIOLOGY

Studies Show:

TBC (Total Body Count) Reduction of

78.99 – 92.50%

By using HOCl {atm plus} Pintaric, Robert et al. “Suitability of electrolyzed oxidizing water for the disinfection of hard surfaces and equipment in radiology.” Journal of environmental health science & engineering vol. 13,1 6. 28 Jan.

2015, doi:10.1186/s40201-015-0160-8

(70)

atm plus:

atm plus

does not cause irritation of eyes, skin or respiratory systems

HOUSEKEEPING

‘HOCl {atm plus} does not leave toxic residues’

• Studies show only 40 – 50% of surfaces are cleaned

• Wiping takes time

• Staff shortages reduces efficacy

• Inappropriate dilution causes inefficient cleaning

MEDICAL: WARDS

HOCl MAY BE SPRAYED ON AND LEFT WITHOUT WIPING

• Reduces cleaning time

• Does not reinfect with dirty cloth

(71)

atm plus:

atm plus

does not cause irritation of eyes, skin or respiratory systems

HOUSEKEEPING

‘HOCl {atm plus} is efficient in 15 seconds ’

MEDICAL: WARDS

HOCl MAY BE SPRAYED ON:

• Beds

• Equipment

• Linen

• Surfaces

• Bathrooms

• Hands

(72)

atm plus:

atm plus

spray, wipe and dry: NO RINSE REQUIRED

• wash and rinse fruit and vegetables – NO RESIDUE ON PRODUCT

• disinfect and clean equipment – PREP AREAS, SORTING – PPE, BOOTS, TOOLS

• disinfect KITCHENS, TROLLEYS AND TRAYS

‘.’

FOOD PROCESSING

(73)

atm plus:

atm plus

use at max 60PPM on fresh produce

Journal of Advances in Agriculture Vol 9 (2018) ISSN: 2349-0837

Lettuce was treated with tap water (c) anolyte without salts (1) and HOCl {atm plus} (2) for 15 minutes

Disinfection of leafy vegetables with activated waters

c 1 2 2 c

Lettuce after 24 hours of application Lettuce after 1 week of application

Conclusion: vegetables treated with HOCl stay FRESH (free of bacterial decay) for longer

FOOD PROCESSING

(74)

atm plus:

atm plus

should be used with an appropriate degreaser

ON CONTACT SURFACES

‘For fresh meats, a commonly used antimicrobial is organic acids like HOCl {atm plus}

• Reduces biofilm formation – with SUBMERSIVE treatments of 30 seconds

• Eliminates bacterial contamination

• Effectiveness is not dependent on surface type o Plastic cutting boards

o Wooden cutting boards o Steel preparation areas

FOOD PROCESSING

(75)

POULTRY

(76)

(HOCl)

Hypochlorous Acid

atm plus

has a broad spectrum anti-microbial use

also known as

• electrolyzed water / electrolyzed reduced water

(ERW, EW)

• electrochemically activated water

(ECA)

• anolyte

(AEW, NEW, SAEW)

(77)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• No polar charge

• Low molecular weight

PERFECT structure to penetrate CELL WALLS

• HOCl is a WEAK ACID

• At a pH of 4 – 8.5 most available Chlorine is HOCl

NO RESIDUE after dissolving in water

• Solution stays active for 7 – 10 DAYS

(78)

(HOCl)

Hypochlorous Acid

atm plus

most effective disinfectant in the chlorine family

• HOCl diffuse through cell membrane

• Without a polar charge it is not repelled

• OCl- (BLEACH) is unable to penetrate cell membrane due to negative charge

• Bleach can only clean on the EXTERIOR

• HOCl acts from INSIDE

hypochlorousacid.com/about

(79)

(HOCl) NATURE of Hypochlorous Acid

“Hypochlorous acid is LETHAL to every pathogen

it has been tested against but completely HARMLESS

to humans and other mammals.”

• Natural component of our own immune systems

• Fights against infection

• Reduces inflammation

• Bio-degradable in the environment

atm plus

organic, lethal, cost effective

(80)

phagocytosis

[ fag-uh-sahy-toh-sis ]

noun

Physiology. the ingestion of a smaller cell or cell fragment, a microorganism, or foreign particles by means of the local infolding of a cell's membrane and the protrusion of its cytoplasm around the fold until the material has been surrounded and engulfed by closure of the membrane and formation of a vacuole:

characteristic of amoebas and some types of white blood cells.

• Neutrophils (WHITE BLOOD CELLS) seek out pathogens

(VIRUSES AND BACTERIA) and destroy them using HOCl

• HOCl causes necrosis (RUPTURING OF THE CELL) and destroys the cell contents

• While disinfecting, HOCl is {OXIDISED} and consumed

• The only by-product is slightly salty water

(81)

EFFECTIVENESS OF HOCl

atm plus

80 – 100 times more effective than bleach

atm plus

disinfects and destroys:

✓ VIRUSES

✓ BACTERIA

✓ MOULDS

✓ FUNGI

✓ SPORES

✓ BIOFILMS

✓ INFECTION

✓ RESISTANCE/TOLERANCE

✓ PATHOGENS BENEATH BIOFILMS

✓ FERMENTATION IN STORAGE

defends against:

(82)

atm plus

80 – 100 times more effective than bleach

PROVEN EFFECTIVE AGAINST SARS-CoV-2

Michael S. Block, Brian G. Rowan, Hypochlorous Acid: A Review,

J Oral Maxillofac Surg, 10.1016/j.joms.2020.06.029

‘The surgeon needs to have an inexpensive, available, nontoxic, and practical disinfectant that is effective in sanitizing against the COVID-

19 (Coronavirus Disease 2019) virus.’

‘The results indicate that this material can be used with a high predictability for disinfecting against the COVID-19 (Coronavirus

Disease 2019) virus.’

Chan K-H, Sridhar S, Zhang RR, Chu H, Fung AY-F, Chan G, Chan JF-W,

To KK-W, Hung IF-N, Cheng VC-C, Yuen K-Y, Factors affecting stability and infectivity of SARS- CoV-2,

Journal of Hospital Infection,

https://doi.org/10.1016/j.jhin.2020.07.009.

The latest peer approved scientific papers conclusively show that HOCL effectively kills the SARS-Covid 2 virus. The papers

also compare HOCL to other disinfectants showing its comparative performance with other disinfectants such as

bleach.

(83)

atm plus

effective at 25PPM to 200PPM depending on use HOCl concentrated into a

6 gram

dissolvable tablet

the effervescent tablet

atm plus

1 tablet = 12.5l of disinfectant

consistent solution at 100PPM every time

easy STORAGE low TRANSPORT COSTS

active for 7 – 10 DAYS after dissolving then returns to pure water

1 year SHELF LIFE in tablet form

(84)

to name a few…

USES OF atm plus

atm plus

100% organic, bio-degradable, MRL FREE

• DISINFECTING any and all surfaces

• AGRICULTURAL

• LIVESTOCK

• MEDICINAL / DENTISTRY

fresh fruit / veg preparation hydroponics / irrigation pesticidal treatment

control / reduction of disease

improves digestion / feed conversion ratios increase livestock yields

mouthwash / wound care waterline disinfection scrubbing in

(85)

to name a few…

USES OF atm plus

atm plus

safer exposure to humans than regular disinfectant

• HORTICULTURE

• WATER TREATMENT

• FACILITIES

• TRANSPORT

increase shelf life

reduces rotting / infection

shopping centres accommodation office buildings

airlines / airports public transport

shipping / cruiseliners

(86)

atm plus:

atm plus

gentle, effective, safe – NO PPE NECESSARY

GENERAL USE

atm plus CAN BE USED TO CLEAN AND SANITIZE:

• Floors and walls

• Preparation areas

• Workers’ hands, clothes and shoes

• Food contact surfaces

‘As a Disinfectant/Sterilant, HOCl has greater killing power than Chlorine, Chlorinated Water, Chlorine Dioxide, Sodium Hypochlorite, Hydrogen Peroxide and Ozone’

(87)

atm plus:

atm plus

reduces overall mortality rates

POULTRY

POULTRY

• Elimination of the requirement to purchase and store toxic, man-made sanitizing and disinfecting chemicals

• Control de-feathering by fog-misting – IT DESTROYS AEROBIC AND ANAEROBIC BACTERIA

• Disinfection of feed – TO KILL MICROBIAL PATHOGENS

• Better digestion and feed conversion ratio

• Disinfection of drinking water

‘As a Disinfectant/Sterilant, HOCl has greater killing power than Chlorine, Chlorinated Water, Chlorine Dioxide, Sodium Hypochlorite, Hydrogen Peroxide and Ozone’

(88)

atm plus:

atm plus

litter and manure can be sprayed daily for microbial and odour control

GENERAL SANITIZING

Fogging and spraying the building interior will:

‘The use of HOCl {neutral anolyte} provides the poultry farm with an absolute perfect hygiene status’

POULTRY

• Encapsulate and kill bacteria and other microbial pathogens

• Remove odours

• Bind dust and encompassed bacteria

• Improve quality of breathing air

(89)

atm plus:

atm plus

eliminates contamination from water sources and the environment

DRINKING WATER

Purification of drinking water systems – DESTRUCTION OF BIOFILM BUILDUP AND ALGAE IN PIPES

Pathogens do not develop a resistance to HOCl – BIOFILM AND ALGAE DO NOT REOCCUR

Prevention of clogged drinking nozzles

Removes LIME SCALE and MINERAL DEPOSITS

Coliform bacteria is prevented from being conveyed by the birds

‘Poultry will, on average, consume twice as much water as any other substance..’

POULTRY

(90)

atm plus:

atm plus

recommended use at 100 -

200PPM

DESTRUCTION OF BIOFILM AND SCALE IN WATERING SYSTEMS

before treatment after treatment

POULTRY

(91)

atm plus:

atm plus

recommended use at 100 -

200PPM

DESTRUCTION OF BIOFILM AND SCALE IN WATERING SYSTEMS

before treatment

before treatment

after treatment

after treatment

POULTRY

(92)

atm plus:

atm plus

does not change the characteristics of drinking water

Continuous injection of 2 – 3% of HOCl solution is sufficient to kill all pathogens

Anolyte has a residual biocidal effect that stays active in the system for CONTINUAL SANITATION

High ORP (Oxidation-Reduction Potential) of HOCl in the water has more ability to DESTROY foreign contaminants

There is a direct relationship between the ORP level and the Coliform count in water.

HOCl has an ORP of +600 to +1200mV

Kills 100% of choliform bacteria in 30 seconds

‘Adding HOCl to the drinking water improves animal health and increases weight gain’

POULTRY

ORP Level Coliform count in 100 ml of water

200 300

300 36

400 3

600 0

(93)

atm plus:

atm plus

sans 51276 (BACTERIA) sans 51650 (FUNGUS) sans 51650 (SPORES) en 1276 (VIRUS)

EFFECTIVE AGAINST:

Diseases

Bordetellosis

Coryza

Blue Comb

Salmonella

Cholera

New Castle

Intestinal Tract Enteritis

Not limited to..

POULTRY

(94)

atm plus:

atm plus

18 liters sprayed over 1 ton of feed for optimal disinfection

FOOD PRESERVATION:

HOCl is used for food preservation without affecting the quality of the grain

Added acidity inhibits ‘breathing’ of the grain

This results in preservation of vitamins that usually disappear when temperatures are higher than 50 °C

Birds grow faster as they can utilize feed more efficiently – MORE RAPID WEIGHT GAIN

‘Common performance indicators show a reduction in number of days ‘on feed’ to achieve the same bird mass.’

POULTRY

(95)

atm plus:

atm plus

Recommended use 100PPM

EGG PRODUCTION

• Higher egg per bird average – UP TO 6% INCREASE

• Better shell quality – DECREASE IN EGG BREAKAGE

• Improved egg mass – UP TO 6g HEAVIER PER EGG

POULTRY

Laying hens that consume drinking water disinfected with HOCl {atm plus} has:

Eggs that are immersed in HOCl {atm plus} solution for 5 minutes

• Prevents Salmonella from penetrating eggs in first 3 days

• Destroys existing traces of Salmonella

(96)

atm plus:

atm plus

pH will play a significant role

BENEFITS FOR POULTRY FARMING

• Better overall flock HEALTH

• Lower MORTALITY rate

• Less BRONCHITIS outbreaks

• Lower average MEDICINAL costs

• Better health of staff – No exposure to unnecessary chemicals

POULTRY

(97)

Why Hypochlorous Acid?

Hypochlorous Acid is one of the most natural and effective known biocides known to man. It eradicates all bacteria, mycobacteria, spores, fungi, viruses – even the tough Clostridium difficile – within 15 seconds. It disinfects 80 to 100 times better than bleach (Sodium Hypochlorite) and is 100% safe.

Hypochlorous acid oxidizes (explodes) the cell wall of all pathogens causing necrosis (rupturing of the cell) or apoptosis (programmed cell death) and destroys them. Though viruses are not technically living

organisms, they too are destroyed by hypochlorous acid.

Despite this destructive potential, our bodies use this defense throughout life.

Hypochlorous acid is naturally produced by our white blood cells and is an essential part of our Immune System.

This process is called phagocytosis and is one of humans' most symbiotic actions – white blood cells release this natural oxidant to eliminate pathogens while being inherently harmless, unlike most other disinfectants which are toxic.

When a wound breaks human skin, it creates a gateway for harmful pathogens to invade human cells. Neutrophils, which are a type of white blood cell, travel in the blood to the site of the wound where the pathogens are invading. When an invading pathogen or infection

threatens a human cell, the body's immune system responds by destroying the pathogen before it can harm the cell. The invading pathogens are engulfed by white blood cells through a process called phagocytosis. Once engulfed, the white blood cell produces an oxidant,

hypochlorous acid. Hypochlorous Acid is a biocide and kills the microbial pathogen within milliseconds of contact. This antimicrobial process is called the Oxidative Burst Pathway.

You can use hypochlorous for surface disinfection! Hypochlorous can be sprayed liberally on all surface types and pathogens are neutralized within seconds.

(98)

Hypochlorous can also be used for dental waterlines – it allows you to eliminate biofilm and legionella with no side effects!

Other uses: impression disinfectant, instrument soak, ultrasonic baths, disinfect root canals, removing biofilms from implant surfaces, mouthrinse (particularly effective post-surgical), and endodontic irrigation.

Hypochlorous acid does not cause irritation to eyes and skin. Even it were ingested it causes no harm. Because it is so safe, it is the ideal sanitizer for direct food sanitation and food contact surfaces. It is also ideal in healthcare where it is used for wound cleansing, eye drops, and patient room disinfection replacing toxic chemicals such as bleach and quaternary ammonium (quats). Sanitation chemicals distributed in concentrated form are toxic and can be hazardous.

Contact with skin or inhalation of fumes can cause irritation. These risks do not exist with hypochlorous acid.

How does HOCL kill mocrobial pathogens?

The Molecule of hypochlorous acid is HOCl. This molecule is unique in that it is neutrally charged unlike hypochlorite (OCl-) which is negatively charged. So why is this important?

Disinfectants and microbial pathogens interact with each other similar to magnets. If you bring together two negatively charged magnets, they will repel each other. Bacteria and hypochlorite (OCl- aka. bleach) are both negatively charged and behave like two negatively charged magnets repelling each other. Hypochlorous acid (HOCl) is neutrally charged and is not repelled by bacteria. HOCl easily penetrates the walls of the bacteria and destroys them with its strong oxidation potential.

(99)

Applications

Sanitising Tunnels Large Area Misting Produce Processing

Meat Processing Food Contact Surfaces

Biofilm Control Sanitation

Medical

References

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