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Everolimus induces Met inactivation by disrupting the FKBP12/ Met complex

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Figure

Figure S2C). Interestingly, a comparison between the
Figure 2: Everolimus inhibits phospho-Met phosphorylation via FKBP12. A. Colocalization analysis performed by immunofluorescence analysis: 786-O cells were grown on glass cover slips for 24 hours, then double-stained with anti-Met receptor and anti-FKBP12
Figure 3: Everolimus does not inhibit Met phosphorylation in human everolimus resistant cancer cell lines
Figure 4: Met inhibition restores sensitivity to everolimus in resistant cell lines. A
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