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Original Article MicroRNA-539 suppresses osteosarcoma cell invasion and migration in vitro and targeting Matrix metallopeptidase-8

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Figure

Figure 1. miR-539 expression in OS tissues and cell lines. A. Relative expression of miR-539 in 15 paired tissues in comparison with corresponding adjacent normal tissues
Figure 2. Overexpression of miR-539 inhibits in vitro growth of MG-63 cells. A. MG-63 cells were transfected with miR-539 or miRNA controls, respectively
Figure 3. Ectopic miR-539 expression inhibits invasion and migration of MG-63 cells. A
Figure 4. MiR-539 directly targets MMP8 mRNA and inhibits its expression. A. The putative miR-539-binding sites in the 3’-UTR of MMP8 mRNA was shown

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