5
TH
BIENNIAL
CONFERENCE OF THE
INTERNATIONAL
SOCIETY FOR
BIPOLAR DISORDERS
14 - 17 March 2012, Istanbul - Turkey
Istanbul Lutfi Kırdar
Convention & Exhibition Center
FINAL PROGRAM
WELCOME
Dear Colleagues,
We would like to welcome you to the 5th Biennial Conference of the International Society for Bipolar Disorders and İstanbul, Turkey for this 4 day program from 14 - 17 March 2012. We hope you enjoy your time in İstanbul, the melting pot of continents and cultures over centuries. The Istanbul Lufti Kirdar Convention and Exhibition Center will serve as the sole facility for all conference related activities, including pre-conference workshops, ISBD membership, administrative and task force meetings, and satellite symposia. The ISBD is committed to inclusiveness in all its activities, and draws on its chapters and internationally recognized leaders in the field to bring you an outstanding scientific program.
As referenced above, ISBD will again host a full day of activities prior to the opening ceremony of the meeting, which are part of what make the ISBD meetings a unique experience for attendees. We have arranged a series of pre-conference workshops on topics including women’s health, mood stabilization and comorbidity, an experts’ course for young clinicians, chronotherapeutic techniques in the management of bipolar disorder, and advancement clinical topics and future trends in bipolar disorder. These workshops will offer participants the opportunity for a more interactive experience, with opportunities to discuss case vignettes. ISBD members will also not want to miss the annual General Membership Meeting, which will be held on the 14th of March at 16:00 in the Dolmabahce
C Meeting Room.
Among the highlights of the conference are 4 keynote presentations, including a child and adolescent debate, a bipolar spectrum session, US National Institute of Mental Health (NIMH) Updates, and a Word Psychiatric Association (WPA) address to the congress. The meeting will also feature engaging core symposia on topics including optimizing functional outcomes, interpreting clinical trials, DSM-V updates, molecular genetics, neuroimaging, and advocacy. As in years past, ISBD will also be holding an awards ceremony and special concurrent session for the winners of the Samuel Gershon Awards for Junior Investigators, as well as an International Society for Affective Disorders (ISAD) session.
We trust you will find the conference to be a memorable, informative and enjoyable event.
President : Mauricio Tohen
Co-chairs : Ayşegül Özerdem and Sophia Frangou Treasurer : Ihsan Salloum
ISBD 2012 CONFERENCE OFFICIALS
President: Mauricio Tohen, MD, DrPH, MBA (USA)
Co-Chair: Aysegul Ozerdem, MD, PhD (Turkey)
Co-Chair: Sophia Frangou, MD, PhD, FRCPsych (United Kingdom)
Treasurer: Ihsan Salloum, MD, MPH (USA)
Local Organizing Committee
Omer AYDEMİR, MD (Turkey)Kaan KORA, MD (Turkey) Timuçin ORAL, MD (Turkey) Simavi VAHİP, MD (Turkey) Olcay YAZICI, MD (Turkey)
Caleb Adler, MD University of Cincinnati USA
Fisun Akdeniz, MD
Ege University School of Medicine Affective Disorders Unit Turkey Hagop Akiskal, MD VA Psychiatry Service USA Carlo Altamura, MD University of Milan Italy Michael Bauer, MD, PhD Technische Universitat Dresden Germany
Robert Belmaker, MD
Ben-Gurion University of the Negev Israel
Michael Berk, MD, PhD Barwon Health Swanston Centre Australia
Boris Birmaher, MD University of Pittsburgh School of Medicine
Pittsburgh, Pennsylvania Joseph Calabrese, MD University Hospitals Case Medical Center
Case Western Reserve University USA
Francesc Colom, PsyD, MSc, PhD
Institute of Neurosciences, Hospital Clinic
University of Barcelona Spain
Allen Doederlein
Depression and Bipolar Support Alliance (DBSA),
USA
Sophia Frangou,MD, PhD, FRCPsych
King’s College London UK
Ellen Frank, PhD
University of Pittsburgh School of Medicine USA Mark Frye, MD Mayo Clinic USA Kyooseob Ha, MD, PhD Seoul National University South Korea
Chantal Henry, MD, PhD Pole de psychiatrie Hospital de Chennevier
France
David Kupfer, MD
Univ. of Pittsburgh School of Medicine USA
Rasmus Licht, MD, PhD Aarhus University Psychiatric Hospital Denmark Andrew McIntosh, MD Edinburgh University Charles Nemeroff, MD, PhD University of Miami USA Willem A. Nolen, MD, PhD University Medical Center Groningen The Netherlands
Tezer Orhan Lithium Association Turkey
Ayşegül Özerdem, MD, PhD Dokuz Eylul University Medical School
Turkey
Natalie Rasgon, MD, PhD Stanford University School of Medicine USA
Marcella Rietschel, MD Heidelberg University/Medical Faculty Mannheim
Germany
Pedro Ruiz, MD
University of Miami Miller School of Medicine
USA Ihsan Salloum, MD, MPH University of Miami USA
Manuel Sanchez de Carmona, MD ISBD Mexican Chapter
Mexico
Verinder Sharma, MB, BS, FRCP (C) University of Western Ontario Canada
Lut Tamam, MD
Cukurova University Faculty of Medicine Turkey
Eric Taylor, MD King’s College London UK
Mauricio Tohen, MD, DrPH, MBA University of Texas
USA
Simavi Vahip, MD Ege University Medicine Faculty Turkey
Eduard Vieta, MD, PhD University of Barcelona Spain
Lakshmi Yatham, MD, FRCPC The University of British Columbia Canada
Eric Youngstrom, PhD University of North Carolina USA
Carlos Zarate, MD National Institute of Mental Health, Maryland
USA
ACKNOWLEDgEMENTS
We wish to express our gratitude to the following companies who through their generosity, have helped to make this Congress possible
Platinum Level
Other Sponsors
Turkish Advocacy Forum Sponsor Official Congress Airline
Exhibitors
CINP
BIPOLAR DISORDERS ASSOCIATION OF TURKEY BIPOLAR LIFE ASSOCIATION TURKEY INTERNATONAL SOCIETY FOR BIPOLAR DISORDERS
LILLY ILAC LITHIUM SOCIETY TURKEY
MUSTAFA NEVZAT
COMPANY SPONSORED SATELLITE SYMPOSIA
Wednesday, March 14
th2012, Anadolu Auditorium
19:30-21:00
“Making the right decisions to prevent recurrence in the long-term treatment of bipolar disorder”
Chair: Heinz grunze Speakers: Christoph Correll, Eduard Vieta, Michael gitlin,
Thursday, March 15
th, 2012, Anadolu Auditorium
11:45 – 13:15
“A Journey from Pole to Pole: Today’s challenging patient”
Chair: Mauricio Tohen Speakers: Timucin Oral, Eduard Vieta, Roger McIntyre 19:00 – 20:30
“A Journey from Pole to Pole: Travelling to the Future”
Chair: Joseph Calabrese Speakers: Ali Saffet gonul, Lakshmi Yatham, Francesc Colom
Friday, March 16
th, 2012, Anadolu Auditorium
12:45 – 14:15
“Time to revisit the definition and treatment of bipolar I disorder in a Multidimensional way”
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CONFERENCES TAKE
YOU,
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CAN TAKE YOU
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INTERNATIONAL SOCIETY FOR BIPOLAR DISORDER
MEETINg AT THE CONgRESS
Wednesday, March 14, 2012
16:00 - 17:00 ISBD Membership Meeting Dolmabahce C, on the 1st Floor
CME ACCREDITATION
The 5th Biennial Conference of the International Society for Bipolar Disorders’ is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS), www.uems.net The 5th Biennial Conference of the International Society for Bipolar Disorders’ is designated for a maximum of 15 hours of European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.
Through an agreement between the European Union of Medical Specialists and American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME credit to AMA credit can be found at www.ama-assn.org/go/internationalcme Live educational activities, occurring outside of Canada, recognized by the UEMS-EACCME for ECMEC credits are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of The Royal College of Physicians and Surgeons of Canada.
EACCME credits
Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity. The EACCME credit system is based on 1 ECMEC per hour with a maximum of 3 ECMECs for half a day and 6 ECMECs for a full-day event.
SAMUEL gERSHON AWARDS FOR JUNIOR INVESTIgATORS
The International Society for Bipolar Disorders (ISBD) recognizes the vital role of developing the next generation of leaders in the field of bipolar disorders and will offer 4 awards for original research publication submissions. In order to promote research interest in bipolar disorders in developing countries, two of the awards will be reserved for those from low and middle-income countries, as defined by the 2011 World Bank Classification. The awards are presented in conjunction with the 5th Biennial Conference of the International Society for Bipolar Disorders to be held in Istanbul from 14-17 March 2012.
The Samuel gershon Awards 2012 Winners
• Rasim Somer Diler, MD
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA, USA
• Jan-Marie Kozicky, PhD
Department of Psychiatry, University of British Columbia, Vancouver, BC Canada • Pedro Vieira da Silva Magalhães, MD, PhD
National Institute for Translational Medicine, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
• Cristian Zeni, MD
Federal University of Rio Grande do Sul, Brazil
GENERAL
INFORMATION
gENERAL INFORMATION
Venue
Istanbul Lütfi Kırdar Convention & Exhibition Centre (ICEC) Harbiye, 34267, Istanbul - Turkey
Tel: +90 212 3731100 www.icec.org Registration Desk
Registration desk will be open during the below dates and times at the main foyer of the Congress Center, Istanbul Lutfi Kirdar Convention Center - ICEC.
Registration Desk Hours
March 14, 2012
Registration for Workshops, 07.30 – 09.00
Registration for ISBD 2012 Starting From 13.00 to 19.30
March 15 & March 16, 2012
Registration for ISBD 2012 From 07.30 - 19.00
March 17, 2012
Registration for ISBD 2012 From 07.30 - 13.00 Name Badges
Upon registering you received your Congress kit in which you will find your name badge. You are kindly requesting to wear name badges during the conference. Please note that delegates without a name badge will not be allowed to enter the conference venue or sessions.
Language
The official language of the congress is English. Exhibition
The exhibition will be open at the main foyer of the Congress Center, Istanbul Lutfi Kirdar Convention Center - ICEC.
Wednesday, March 14 17.00 – end of Welcome reception March 15- March 16 08.00 – 18.00
March 17 08.00 – 13.00
Accompanying Persons Program
Registered accompanying persons will be able to attend the Opening Ceremony, Welcome Reception. Accompanying persons will be participate 2 daily tours as below:
TOUR 01 - THE MAgNIFICENT DOMES OF ISTANBUL
Thursday MARCH 15 TIME : 09:00-13:00 TOUR 02 - OTTOMANIA
Friday, MARCH 16 TIME: 09:00-13:00
(All tours will depart from congress venue).
Certificate of Attendance
Delegates will be able to receive their certificate of attendance from the registration desk Opening Ceremony & Welcome Reception
Opening Ceremony will be organized on March 14, 2012 between 17.00 and 18.00, at the Anadolu Auditorium of ICEC. After the ceremony the Welcome Reception will be organized at the main foyer of the Anadolu Auditorium at ICEC. All registered delegates and accompanying persons will be able to attend to these events. Please wear your name badges for entrance to the Welcome Reception.
Lunch
Lunch boxes will be served on March 15th & March 16th. However, cash bars and A la Carte restaurant will be
available in the conference venue for the service of attendees.
There are also lots of different cuisine and restaurant options around the conference venue. Necessary information reaching to various options for lunch can be obtained from the Information Desk.
Posters
The Poster boards are sponsored by J&J. Posters are located in the 1st floor of the congress center. Poster Sessions will take place on Thursday, March 15 and Friday, March 16.
Slide Control Room / Speaker Ready Room
Delegates who will present their papers should submit their presentation files at least two hours before their presentation. The Slide Control Room will be on the first floor of the conference venue and the name of the room is Dolmabahce B. It is advised to load the presentations to the Speaker Ready Room at least two hours
before the session starts. If your presentation is early in the morning, it is advised to load the presentation the day before.
Internet Cafe
An internet cafe will be free to use it during the conference. Information & Message Center
This Center will provide up to date information and announcements throughout the Congress and serve as a platform for exchanging messages between the Congress’ participants. The center is located on the main foyer area. Airport - City Center Transfers
Delegates who already purchased airport transfers will be welcomed at the exit of the international arrivals with a board on which the ISBD 2012 logo and name of the delegate will be seen.
No complimentary transfers will be provided from and to the airport. You will have to make your own way to the hotel. The average price for taxi fare from the airport to the hotel to the city center is about ~ 25.-Euros. HAVATAS shuttle buses depart every half an hour from the airport to Taksim Square. One way HAVASTAS tickets are ~7.-Euros per person.
Tour & Transfer Desk
There will be a Tours & Transfers Desk at the registration area where all delegates will be able to purchase departure transfers, change their current departure transfers and also purchase post-conference and daily city tours. This desk will be giving service from March 14, 2012, at 13.00 until the end of the Congress.
Currency & Banking
The national currency in Turkey is Turkish Liras (TL). 1.-EURO = 2,35 TL / 1.-USD = 1,78 TL
Banks can exchange foreign currency and travelers checks with your passport as proof of identity. Commissions are charged at between 1-3 % per transaction. Exchange rates change daily and can be checked in the press. Also Euro can be found and easily can be changed in the exchange offices. Banks are usually open between 09:00 - 12:00 and 13:30 - 17:00 on weekdays. The big retail banks all have ATMs, some of them give cash advances against foreign credit cards.
Communication
If you have a GSM-standard phone capable of operating on the 900MHz and/or 1800MHz band(s), you may be able to use international roaming in Turkey for at least a few weeks. For longer use, you’ll have to register your phone with the Turkish government
Electricity
The electric current is 220V AC with a frequency of 50 Hertz. European standard plugs Type C (European 2-pin) with two round pins are used. 110V AC is also found in some 5 star hotels.
Congress Secretariat
If you have any concerns regarding any request for the Congress please contact Kenes Turkey or visit information desk located on the ground level of the Istanbul Convention Centre.
Kenes Turkey is the official Congress Organizer of The ISBD 2012
Sarı Asma Sok. No 9 Yeniköy, Sarıyer, Istanbul Tel : +90 212 299 9984
Fax : +90 212 299 9977 Email : [email protected] Site : www.kenes.com
LIST OF CONgRESS HOTELS
All Hotels in the list below are in walking distance. All hotel accommodations are included breakfast and VAT. Official check-in time for the hotels is 14.00 hours and check-out is 12:00 noon. All extra expenses such as meals, mini bar, telephone calls, dry cleaning etc. should be paid to the hotels directly before check-out.
Hilton Istanbul Hotel
Cumhuriyet Cad. 34367 Harbiye Tel : 90 (212) 326 71 00
grand Hyatt Istanbul Hotel
Taskisla Caddesi, Taksim, 34437 Tel : 90 (212) 368 1234
Ramada Plaza Istanbul
Halaskargazi Cad. No:63 34373 Sisli Tel : 90 (212) 315 44 44
Konak Hotel
Cumhuriyet Cad. No:75 34437 Elmadag Taksim
Tel : 90 (212) 225 82 50
Larespark Hotel
Topçu Caddesi,No.23 Taksim Tel : 90 (212) 313 51 00
Nippon Hotel
Topçu Caddesi No:6 34437 Taksim Tel : 90 (212) 313 33 00
Titanic Hotel
Lamartin Cad No 47 Taksim 34437 Tel : 90 (212) 238 90 90
Midtown Hotel
Lamartin Cad No13 Taksim 34437 Beyoğlu, Taksim
Tel : 90 (212) 361 6767
greenpark Hotel
Taksim Caddesi No:79/A 34437 Taksim
Tel : 90 (212) 238 9111
Madison Hotel
Receppasa Caddesi No. 15, 34437 Beyoglu, Taksim
90 (212) 238 54 60
Feronya Hotel
Abdülhakhamit cad.no.58 Taksim 34437
Tel : 90 (212) 238 09 01
Cartoon Hotel
Beyoğlu Tarlabaşı Bulv. 36 Taksim Tel : 90 (212) 238 93 28
City Center Hotel
Katip Celebi Mah. Billurcu Sokak No:1 Siraselviler Taksim Tel : 90 (212) 292 27 71
INFORMATION TO PRESENTERS
gUIDELINES FOR ORAL PRESENTATION
1. DISCLOSURE
• A disclosure slide is required for each oral presentation being given for satellite programs and for the main scientific program. The slide should address any relevant financial or other relationships you may have with commercial entities with an interest in the subject matter of your presentation. • The ISBD Scientific Committee requires all Speakers to disclose any advisory or consultancy roles
in the Biomedical Industry during the past 2 years on a PowerPoint slide to be shown immediately at the beginning of the presentation. Other potential conflicts of interest to be reported include: grants, honoraria, shares, paid positions on advisory boards, etc.
2. gUIDELINES
All speakers giving a presentation are requested to load their presentation in the Speaker Ready Room at least two hours before your session starts or the day earlier. Presentations received after this deadline cannot be guaranteed optimal audiovisual support. Experienced and skilled technicians will assist you to transfer and check/correct your presentation.
Please show up 10 minutes prior to the start of the session, identify yourself to the session Chair(s).
Please remember, you are not allowed to connect your own computer to the projector. Projectors for overhead viewgraphs are not available. It is strongly recommended that speakers plan on a 15-20 minute presentation to allow for questions depending on session duration.
The computer driving the display will be a PC (no Macs will be available). If you are a Mac-user, make sure that you check-in early with the Speaker Support Centre for your Mac-presentation to be converted to a pc format. PPT, PPTX, PDF, DOC, DOCX file types are accepted for the presentations. If you are going to use other file types please contact the secretariat. You should also make sure that any and all graphics, multimedia, or other files used by your presentation are included with your presentation. We kindly ask you to bring your files in a USB flash memory or in a CD.
Please use large fonts so they can be read without major effort. The presentations are not stored and are deleted after the meeting.
gUIDELINES FOR POSTER PRESENTATION
1. DISCLOSURE
• ISBD requests poster presenters to disclose potential conflicts of interest, regarding their current poster presentation at the bottom of their poster. This disclosure will allow the audience to take potential conflicts of interest into account when assessing the objectivity of the presentation. Potential conflicts of interest can involve: grants, honoraria, shares, paid positions on advisory boards, etc. • If an author has nothing to disclose, this should also be mentioned as “There are no relevant conflicts
of interest to disclose” at the bottom of the poster.
2. PRESENTATION
Please post your material at mentioned day of presentation, and take it off at the end of the poster session, leaving the pushpins on the board. Material not removed will be destroyed.
One of the authors of each poster paper has to be present to answer questions for the entire duration of the poster session.
Secretariat is not able to provide a printing service. Please bring your printed posters with you. Staff will be on the floor at all times to assist poster presenters.
WORKSHOPS
Workshop-1
Title: “State of the Art in Diagnosing, Assessing and Treating Bipolar Disorder” A Training Course to Become
a Bipolar Expert
Description: To provide an overview for clinicians who are new in the field of bipolar disorder, on how to
diagnose, how to assess and how to treat (psychologically and pharmacologically) patients with bipolar disorder. The course will include 5 sessions of one hour each, consisting of short presentations by experts on the topics, each followed by extensive discussions and including exercises using clinical case vignettes, to ensure much interaction with the course participants.
Chair : Dr. Willem A Nolen, the Netherlands Date & Time : 14 March 2012
Full Day : 09:00 - 16:00 Room : SULTAN 2 HALL
Workshop-2
Title: “Being A Woman With Bipolar Disorder”
Description: To educate the participants on the course of bipolar disorder throughout life cycle in female
patients with a special focus on menstrual cycle/endocrinology/alcohol related problems; teaching ways of working with bipolar women in pregnancy planning, treatment plans and medication use in pregnancy; increase awareness for diagnosing and managing (including pharmacotherapy) bipolar disorder during post-partum period and lactation; updating the audience on the available screening and diagnostic tools for bipolar disorder in post-partum period.
Chair : Dr. Ayşegül Özerdem, Turkey Date & Time : 14 March 2012
Half Day : 12:30 - 16:00 Room : SULTAN 3 HALL
Workshop-3
Title: “Chronotherapeutic Techniques in the Management of Bipolar Disorder”
Description: The acute, pharmacologic treatment of manic and depressive mood states often fails to achieve
quick, complete, lasting and safe remissions. Chronotherapeutic interventions which act by shifting circadian rhythms and sleep, can produce rapid and sustained reductions in affective symptoms. In this workshop, early-career and more experienced clinicians will learn how to expand their therapeutic options with sleep deprivation-based approaches, bright light therapy, dawn simulation and other rhythm-shifting methods. Starting with a brief review of circadian neurobiology and sleep regulation, the workshop will provide detailed, practical information about each chronotherapeutic modality and how they can be combined successfully with pharmacologic treatments. Presentations will include case examples and encourage clinical questions and discussion. Based on the first treatment manual published for this emerging subspecialty (Wirz-Justice et al., 2009), workshop participants will acquire the practical knowledge necessary to know how and when to administer chronotherapeutic interventions in their clinical practices.
Chair : Dr. John gottlieb, USA Date & Time : 14 March 2012 Half Day : 12:30 – 16:00 Room : SULTAN 1 HALL
Workshop-4
Title: “Advanced Clinical Topics And Future Trends In Bipolar Disorders”
Description: Summarize in a comprehensive presentation the new findings and trends in neurobiology,
diagnostic and clinical approaches in bipolar disorders. Discuss the staging model of treatment as a useful clinical algorithm to increase early diagnosis and treatment. Understand the biological markers related to bipolar disorders and its clinical correlation. Review the proposed changes for DSM 5, regarding the mixed episode criteria, and study the new concepts of course specifiers and subsyndromal states. Analyze the dilemma of using antidepressants in bipolar population and the possible consequences they may generate in the course and characteristics of future episodes of the disorder.
Review the new medications that may follow the current pharmacological options for treatment and underline the future research projects, and clinical areas of opportunity for new findings in bipolar disorders.
Chair : Dr. Manuel Sanchez Carmona, Mexico Date & Time : 14 March 2012
Half Day : 08:30 - 12:00 Room : SULTAN 1 HALL
FLOOR
PLANS
ICEC OVERVIEW
EXHIBITON PLAN
1 CINP 2 LILLY ILAC
3 11TH WORLD CONGRESS OF BIOLOGICAL PSYCHIATRY
4 MUSTAFA NEVZAT
5 ISBD - INTERNATONAL SOCIETY FOR BIPOLAR DISORDERS 6 LITHIUM SOCIETY TURKEY
7 BIPOLAR LIFE ASSOCIATION TURKEY 8 BIPOLAR DISORDERS SOCIETY TURKEY
@ internet
COMPANY PROFILES
SPONSORS
ASTRA ZENECA
AstraZeneca
Alderley House, Alderley Park, Macclesfield, Cheshire UK
AstraZeneca is a global, innovation-driven biopharmaceutical business with a primary focus on the discovery, development and commercialisation of prescription medicines for gastrointestinal, cardiovascular, neuroscience, respiratory and inflammation, oncology and infectious disease. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide.
For more information please visit: www.astrazeneca.com
BRISTOL-MYERS SQUIBB & OTSUKA PHARMACEUTICALS EUROPE LTD
Bristol-Myers Squibb Pharmaceuticals
3 rue Joseph Monier 92500 Rueil Malmaison France
Bristol-Myers Squibb (BMS) is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. Around the world, our medicines help millions of people in their fight against cancer, cardiovascular disease, diabetes, hepatitis B, HIV/AIDS, rheumatoid arthritis and psychiatric disorders.
Otsuka Pharmaceuticals Europe Ltd
1, rue Eugène et Armand Peugeot 92508 Rueil-Malmaison Cedex France
Otsuka has a passion for improving the health of people worldwide. We are committed to focusing our research and development on innovative products that address unmet medical needs. Otsuka’s European sales and marketing operations are based in France, Germany, Italy, the Nordics, Spain and the UK.
SPONSORS
LUNDBECK
H. Lundbeck A/S
Otilliavej 9 DK-2500 Valby Copenhagen Denmark Tel: +45 36 30 13 11
www.lundbeck.com
Lundbeck – The Specialist in Psychiatry – Pioneer in Neurology
H. Lundbeck A/S is an international pharmaceutical company truly dedicated and focused in research & development, production, marketing and sales of medicines for diseases within CNS. The company has a long history of creating innovative treatments for depression and anxiety. Cipralex/Lexapro (escitalopram) has confirmed the leading position in this area. Today, more than 200 million patients have been treated with Cipralex/Lexapro. Lundbeck also markets Ebixa (memantine) for treatment of Alzheimer’s disease and Azilect (rasagiline) for treatment of Parkinson’s disease. Lundbeck is currently launching Sycrest (asenapine) in the EU for treatment of bipolar disorder. Furthermore, in the coming year, Lundbeck is expecting to launch Selincro (nalmefene) for the treatment of Alcohol disorders.
JANSSEN RESEARCH & DEVELOPMENT, L.L.C.
At Janssen Research & Development, LLC, we are united and energized by one mission – to discover and develop innovative medicines that ease patients’ suffering, and solve the most important unmet medical needs of our time. As one of the Janssen Pharmaceutical Companies, our strategy is to identify the biggest unmet medical needs and match them with the best science, internal or external, to find solutions for patients worldwide. We leverage our world-class discovery and development expertise, and operational excellence, to bring innovative, effective treatments in five therapeutic areas: cardiovascular and metabolism, immunology, infectious diseases and vaccines, neuroscience, and oncology. We think of the world as our laboratory and we look for innovation wherever it exists. This drives our relentless search for the best science, and our pursuit of collaborations and partnerships. We believe there are no limits to what science can do. And we never lose sight of those who rely most on our discoveries. For more information, visit www.janssenrnd.com .
PFIZER
Pfizer İlaçları Ltd. Şti.
Muallim Naci Cad. No: 55 34347 Ortakoy /IST
Pfizer Turkey has been providing services to Turkish medicine and society with its products and activities since 1957. The company has been continuously contributing to the development of medicine and working for a healthier life through scientific and educational programs, clinical researches and scholarships. Pfizer uses science and its resources worldwide to contribute to health and quality life in every stage of life, and offers its explored, innovative health products to the service of medicine. Biological products, small-molecule drugs and vaccines as well as nutrition and consumer products are included in the wide range of Pfizer products for numerous areas of health and animal health. www.pfizer.com.tr
SPONSORS
EgE ENDUSTRI
Ege Endustri A.S.
Kemalpasa Caddesi No:18, 35060 Pinarbasi, Izmir, Turkiye P: 0090 232 4911400 F: 0090 232 4790468
Ege Endustri, founded in 1974 and based in Izmir Turkey has professionalized on designing, manufacturing and testing of fabricated axles, axle components, axle beams, axle housings and suspension parts for light to heavy duty on and off road truck / bus applications.
The company is %64 owned by Bayraktar Holding and %36 open to public. With two facilities and a total of 600 personnel working at Pinarbasi and Gaziemir Free Zone, Ege Endustri supplies products to Scania, MAN (Trucknology award winner 2009), Daimler, Meritor, Sisu Axles, Axle Tech, Hendrickson and American Axle in multiple locations in Americas, Europe and Asia. The total export figure for 2011 is $ 80,000 which makes up to % 80 of the sales.
EgE FREN
Ege Fren Sanayi ve Ticaret A.Ş.
7405/2 Sokak No.4 Pınarbaşı – Izmir
Ege Fren Sanayi ve Ticaret A.Ş, have been established on January 21st 1987 by Otomobilcilik A.Ş. (%51) an affiliate of Özakat Holding, and Rockwell International Finance Co. (%49)
Shares of domestic shareholder (%51) have been transferred to Hüseyin Bayraktar Yatırım Holding in 1990, and foreign shareholder (%49) to Meritor Automative GmbH on 1997.
Paid capital of the company is 8,000,000 TL at the end of 2004.
Main plant, located in Pınarbaşı-İzmir covers 8,500 sqms on an area of 14,500 sqms, while the 2. plant producing fo export covers 6,200 sqms is Aegean Free Zone at Gaziemir-İzmir.
EXHIBITORS
CINP (THE INTERNATIONAL COLLEgE OF NEUROPSYCHOPHARMACOLOgY)
CINP Central Office
Braeview House 9-11 Braeview Place East Kilbride Scotland UK G74 3XH
CINP is the world’s only global organisation dedicated to neuropsychopharmacology. CINP was established in 1957 in Zurich and had its first international congress in Rome in 1958. It is a membership organisation with widespread support from all over the world. CINP’s mission is to encourage and promote the international scientific study, teaching and application of neuropsychopharmacology. It provides consultation for the better evaluation of all aspects of development and usage of neuropsychiatric drugs, including their biochemistry, pharmacology, safety and therapeutic efficacy. Through these activities CINP seeks to improve and advance research activities to lead to improved patient care.
ISBD
ISBD - International Society for Bipolar Disorders
4601 Baum Blvd, 1st floor Pittsburgh, PA 15213-0168 USA
ISBD is a global network of individuals dedicated to finding ways to improve the lives of those with bipolar disorder through collaboration, research, and education. In addition to individual members, the ISBD has a global chapter network of like-minded organizations formed to meet the unique challenges of treating bipolar disorder in their country/region. As an international organization, ISBD offers networking and collaborative opportunities globally, discounts to ISBD’s Conferences, mentorship and award opportunities for residents, fellows and junior faculty, and access to our online membership directory, quarterly newsletter, and other benefits.
EXHIBITORS
MUSTAFA NEVZAT PHARMACEUTICAL INDUSTRIES, INC. Pak Is Merkezi Prof. Dr. Bülent Tarcan Sok. No 5/1
34349 Gayrettepe - ISTANBUL - TURKEY Tel: (212) 337 3800
Fax: (212) 337 3801 E-mail: [email protected]
Mustafa Nevzat pharmaceuticals, the national pharmaceutical industry in business since 1923, the most established pharmaceutical companies. Turkish pharmaceutical industry has taken many “first” signature and national pharmaceutical industry company is a pioneer in the development of the contribution. Mustafa Nevzat, expert staff and FDA, EMEA today 1400 persons, approved by the authorities, such as raw-material production including all’S MHRA manufacturing facilities with Turkey’s leading manufacturers of finished medicines and pharmaceutical raw materials. Mustafa Nevzat Drug as our mission; our country and the world people to qualify for a healthier and happier life-quality, reliable and cost-effective products to our users
LILLY
Kuşbakışı Caddesi Rainbow Plaza No: 4 Kat: 1 Altunizade - İST
Founded by Eli Lilly in 1876, Indianapolis USA, Eli Lilly and Company is the 10th largest pharmaceutical company in the world. With its close to 40,000 employees worldwide, Lilly makes medicines that help people live longer, healthier, more active lives.
Today, Lilly has manufacturing plants located in 13 countries and R&D facilities in 8 countries. Its products are marketed in 125 countries.
Since the 1950’s, where its products were first distributed in the Turkish market, Lilly’s mission in Turkey was to improve outcomes for individual patients by accelerating the flow of innovative medicines. Founded in 1993, Lilly İlaç brings innovative treatments to patients in the therapeutic areas of CNS (central nervous system), diabetes, endocrinology, oncology, erectile dysfunction, cardiology and osteoporosis.
www.lilly.com.tr
EXHIBITORS
BIPOLAR DISORDERS ASSOCIATION OF TURKEY Simavi Vahip, M.D., Prof.
Ege University School of Medicine Department of Psychiatry Affective Disorders Unit Bornova 35100 İzmir
Bipolar Disorders Association of Turkey is one of the oldest chapters of International Society for Bipolar Disorders (ISBD). The association was founded in 2007 by a group of mental health professionals. The aims of the association are to increase awareness in the community on the cause, course and treatment of bipolar disorders, to facilitate fight against stigmatization and alienation of the patients, to contribute to health policy making processes that are pertinent to chronic mental illnesses including bipolar disorder; to support scientific research and educational programs for professionals. Up to date, the association supported research projects, ran an educational summer school for young clinicians, contributed to the treatment guidelines of bipolar disorder in collaboration with Psychiatric Association of Turkey, and provided educational grant for 50 residents for conference participation.
LITHIUM SOCIETY TURKEY
Lithium Society is the first advocacy oriented body in Turkey, founded by a small group of patients and psychiatrists in Izmir in 1997. It has nearly 75 members consisted mainly by patients and family members. The society’s name is a tribute to lithium, the widely known life saving molecule. The aims of the society are to increase awareness for early diagnosis and treatment of bipolar disorder, provide support for patients and families, and to fight against stigmatization. Lithium society operated locally in Izmir since its establishment with support group meetings for the patients, periodic educational lectures and social activities open to the public. Lithium Club is the artistic arm of the society where patients get together for painting sessions. It has provided a therapeutic environment to many individuals who were otherwise confined to indoors due to adversities of a long lasting course of illness. The strength of the society is the contributions coming from volunteers. However the weak coherence among the members and inefficient financial support have been the major challenges of the society over the years.
EXHIBITORS
BIPOLAR LIFE ASSOCIATION (BLA), TURKEY www.bipolaryasam.org
Bipolar Life Association is a voluntary patient and family organization that incepted in 2007 in Istanbul. A group of psychiatrist, psychologist, nurse, patients and families came together and to educate the community about bipolar disorders. The association focuses on support, education, bring the patients and professional together to help individuals and families affected by bipolar disorders. Most activities continue on web page and with some educational meetings that gathering professionals, patient and families. One of the targets is also build a bridge between patients and specialized mood disorders clinics.
11th WORLD CONgRESS OF BIOLOgICAL PSYCHIATRY
23-27 June 2013 www.wfsbp-congress.org
SCIENTIFIC
PROGRAM
ISBD 2012 SCIENTIFIC PROgRAM
Day 1: Wednesday, March 14, 2012
08:30 – 16:00 Workshops13:00 – 19:00 Registration
16:00 - 17:00 ISBD Membership Meeting DoLMABAHCE C HALL
17:00 - 18:00 OPENINg CEREMONY AnADoLu AuDıTorıuM
Welcome Address: Aysegul Ozerdem
Turkish psychiatry – Achievements and Challenges
Presidential Welcome: Mauricio Tohen
Important updates since 2010 meeting
Awards Presentation: Gershon Awards by M. Tohen, W. nolen
Sponsored by Lundbeck 18:00-19:30 Cocktail Reception and Buffet
Welcome Reception will be organized at the main foyer of the Anadolu Auditorium at ICEC.
19:30-21:00 EVENINg SYMPOSIUM ANADOLU AUDITORIUM
Sponsored by BMS/OTSUKA
“Long-term success in preventing recurrence of mood events in bipolar disorder”
Chair: Heinz grunze
Introduction and Welcome: Heinz grunze, UK
Is Switching Antipsychotic Medications in Stable Patients Ever a good Idea? Christoph Correll, USA
Choosing Long-term Treatment in Bipolar I Disorder on the Basis of Predominant Polarity
Eduard Vieta, Spain
Q&A Heinz Grunze
Assessing the Evidence for Maintenance Treatment in Bipolar I Disorder: The Impact of Clinical Trial Design
Michael gitlin, USA
Q&A Heinz Grunze
Assessing the Evidence when Creating guidelines for Maintenance Treatment in Bipolar I Disorder: What Do We Know and What Don’t We Know?
Heinz grunze, UK
Q&A Session All faculty
Summary and Meeting Close Heinz Grunze
Day 2: Thursday, March 15, 2012
08:00 – 09:00 KEYNOTE 1 ANADOLU AUDITORIUM
Childhood Bipolar Debate
Moderators: Eric Youngstrom, University of North Carolina, USA Michael Wong, Queen Mary Hospital, Hong Kong, Hong Kong S.A.R What is pediatric bipolar disorder?
Boris Birmaher, University of Pittsburgh School of Medicine, Pittsburgh,
Pennsylvania
What is pediatric bipolar disorder? Eric Taylor, King’s College London, UK
QUESTION & ANSWERS
09:00 – 10.00 CORE SYMPOSIUM 1 ANADOLU AUDITORIUM
Optimizing Functional Outcomes in BD
Chair: Eduard Vieta, University of Barcelona, Spain Lifestyle factors in optimizing therapeutic outcomes Michael Berk, Barwon Health Swanston Centre, Australia Psychoeducation in Bipolar patients
Francesc Colom, Institute of Neurosciences, Hospital Clinic, University of
Barcelona, Spain
Functional remediation for bipolar disorder Eduard Vieta, University of Barcelona, Spain
QUESTION & ANSWERS 10:00 – 10:15 Coffee Break
Day 2: Thursday, March 15, 2012
10:15 – 11:15 CORE SYMPOSIUM 2 ANADOLU AUDITORIUM
Interpreting clinical trials in bipolar disorder/methodological issues in clinical trials in bipolar disorder
Chair: Olcay Yazici, University of Istanbul, Istanbul Medical School, Istanbul, Turkey Design of Clinical Trials in bipolar disorders
Mauricio Tohen, University of Texas, USA
Lithium and Anticonvulsant Mood Stabilizers Lamotrigine and Divalproex for Bipolar Depression
Joseph Calabrese, Case Western Reserve University, USA
QUESTION & ANSWERS 11.15 – 11:45 Break
11:45 – 13:15 SATELLITE SYMPOSIUM ANADOLU AUDITORIUM
Sponsored by ASTRA ZENECA
“A Journey from Pole to Pole: Today’s Challenging Patient”
Chair: Mauricio Tohen
Welcome and introduction
A complex diagnosis Timucin Oral, Turkey
The challenges of acute treatment Eduard Vieta, Spain
The challenge of long-term treatment: complexities and comorbidities Roger McIntyre, Canada
QUESTION & ANSWERS 13:15 – 13:45 Lunch Break
Day 2: Thursday, March 15, 2012
13:45 – 14:15 KEYNOTE 2 ANADOLU AUDITORIUM
Updates from the NIMH
Chair: Willem A. Nolen, University Medical Center Groningen, The Netherlands A Translational Perspective in the Search for Improved Treatments for Bipolar Disorder
Carlos Zarate, National Institute of Mental Health, Maryland, USA
QUESTION & ANSWERS 14:15 – 15:45 CONCURRENT SESSIONS I
14:15 – 15:45 SYMPOSIUM 1 MARMARA HALL
Efficacy versus pragmatic effectiveness trials in the long-term treatment of bipolar disorder.
Chair: Willem A Nolen, University Medical Center Groningen, The Netherlands Efficacy vs pragmatic effectiveness trials in the long-term treatment of bipolar disorder: the valproate story
Andrea Cipriani, University of Verona, Italia
Efficacy vs. pragmatic effectiveness trials in the long-term treatment of bipolar disorder: the lamotrigine story
Rasmus W Licht, Aarhus University Hospital, Risskov, Denmark
Efficacy versus pragmatic effectiveness trials in the long-term treatment of bipolar disorder: The lithium story
Willem A Nolen, University Medical Center Groningen, The Netherlands Efficacy versus pragmatic effectiveness trials - The antipsychotic story Joseph R Calabrese, Case Western Reserve University, USA
Day 2: Thursday, March 15, 2012
14:15 – 15:45 SYMPOSIUM 2 TOPKAPI A HALL
Molecular biology of mitochondrial dysfunction: implication and novel findings in Bipolar disorder
Chairs: Trevor Young, University of Toronto, Canada Michael Berk, Barwon Health Swanston Centre, Australia
Neural basis of behavioral phenotypes of mice with neuron specific accumulation of mtDNA mutations
Tadafumi Kato, RIKEN Brain Science Institute, Wako, Saitama, Japan
Synaptosomal-associated protein 25 and Oxidative Damage in bipolar disorder Ana Cristina Andreazza, University of Toronto, Canada.
Novel therapeutics opportunities for bipolar disorder: New research data Michael Berk, Barwon Health Swanston Centre, Australia
A multi-disciplinary approach to studying mitochondrial abnormalities in bipolar disorder
Dost Ongur, Bruce Cohen, McLean Hospital/Harvard Medical School, USA
QUESTION & ANSWERS
Day 2: Thursday, March 15, 2012
14:15 – 15:45 SPECIAL SESSION DOLMABAHCE C HALL
Samuel gershon Awards for Junior Investigators
Sponsored by LUNDBECK
Chair: Simavi Vahip, Ege University Medicine Faculty, Turkey
Neural Activity During Emotion Processing in Bipolar versus Unipolar Depression in Adolescents
RS Diler, ML Phillips, B Birmaher, C Ladouceur, J Almeida, D Axelson
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA, US
Executive function deficits and morphological brain changes in patients with bipolar I disorder following recovery from a first manic episode
J Kozickya, TH Haa,b, IJ Torresa,c, DJ Bonda, RW Lama, LN Yathama
aDepartment of Psychiatry, University of British Columbia, Vancouver, BC Canada, bDepartment of Psychiatry, Seoul National University Bundang Hospital, Korea, cResearch Department, Riverview Hospital, British Columbia Mental Health and
Addictions Services, Coquitlam, BC Canada
A nested population-based case-control study on peripheral inflammation markers and brain-derived neurotrophic factor in early-stage mood disorders PV Magalhãesa, K Jansenb, RT Pinheirob, gR Friesa, AL Teixeirac, RA da Silvab,
F Kapczinskia
aNational Institute for Translational Medicine, Hospital de Clínicas de Porto Alegre,
Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; bPrograma de
Pós-Graduação em Saúde e Comportamento, Universidade Católica de Pelotas, Brazil; cLaboratory of Immunopharmacology, Institute of Biological Sciences,
Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
Brain-Derived Neurotrophic Factor in Juvenile Bipolar Disorder and Attention-Deficit Hyperactivity Disorder: differentiation using BDNF serum levels, and Val66Met polymorphism
CP Zeni, S Tramontina, BW Aguiar, A Salatino-Oliveira, gF Pheula, M Hutz, FP Kapczinski, LA Rohde
Federal University of Rio Grande do Sul, Brazil QUESTION & ANSWERS
Day 2: Thursday, March 15, 2012
14:15 – 15:45 PARALLEL 1 TOPKAPI B HALL
Multiple Co-morbidities in bipolar disorder: diagnostic and treatment challenges
Chair: Ihsan Salloum, University of Miami, USA
Optimizing treatment outcome for bipolar disorder with comorbid addictive disorders
Ihsan Salloum, University of Miami, USA
Impulse control disorders comorbidity in bipolar disorder Lut Tamam, Cukurova University Faculty of Medicine, Turkey The Journey of Addiction in Bipolar Disorder
Mark Frye, Mayo Clinic, USA
QUESTION & ANSWERS 15:45 – 16:00 Coffee Break
16:00 – 17: 30 CONCURRENT SESSIONS II
16:00 – 17: 30 SYMPOSIUM 3 MARMARA HALL
Modern Clinical Management of Bipolar Disorder
Chairs: gin S Malhi, University of Sydney, Australia Mark Frye, Mayo Clinic, USA
Treatment of Mania and Mixed States Roger McIntyre, University of Toronto, Canada
Treatment Options for Acute Depression in Bipolar Disorder Michael Bauer, Technische Universität Dresden, Germany Maintenance Treatments in Bipolar Disorder
Michael gitlin, Geffen School of Medicine at UCLA, USA The treatment of Complex Bipolar Disorder
gin Malhi, University of Sydney, Australia
QUESTION & ANSWERS
Day 2: Thursday, March 15, 2012
16:00 – 17: 30 SYMPOSIUM 4 TOPKAPI A HALL
Development and determinants of psychopathology in prospective bipolar offspring cohorts
Chairs: Manon Hillegers, Universitair Medisch Centrum Utrecht, the Netherland Ketil J. Oedegaard, Haukeland University Hospital, Norway
The Pittsburgh Bipolar Offspring Study
Boris Birmaher, University of Pittsburgh School of Medicine, Pittsburgh,
Pennsylvania
Attachment, Temperament, and Cortisol Profiles in the offspring of bipolar parents
Sarah Doucette, Dalhousie University, Canada,
Predictors of the longitudinal course of mood disorders in children and adolescents
Martin Preisig, University Hospital Center and University of Lausanne, Switzerland Prevalence and course of psychopathology in a prospective Dutch bipolar offspring cohort - A 12 year follow-up
Manon Hillegers, Department of Psychiatry, University Medical Center Utrecht,
Utrecht, The Netherlands QUESTION & ANSWERS
Day 2: Thursday, March 15, 2012
16:00 – 17: 30 BREAKINg NEWS 1 DOLMABAHCE C HALL
BREAKINg NEWS 1 (Oral Presentations)
Chair: gustavo Vazquez, University of Palermo, Buenos Aires, Argentina The effect of lithium and age on brain volume in patients with bipolar disorder L Abramovic, NEM van Haren, MPM Boks, F Bootsman, HG Schnack, R Brouwer, HE
Hulshoff Pol, RS Kahn
Psychiatry department, University Medical Centre Utrecht, Utrecht, The Netherlands
Impact of first-episode polarity on clinical features associated to suicide attempts in bipolar disorder type I patients
LN Abreua, FG Nerya, AM Scippab, F Kapczinskic, B Lafera.
aBipolar Disorder Research Program, Institute of Psychiatry, University of São
Paulo School of Medicine, São Paulo, Brazil, bTeaching Hospital-Psychiatry
Service, Federal University of Bahia, Salvador, Brazil, cBipolar Disorder Program,
Department Of Psychiatry, Federal University of Rio Grande do Sul, National Institute for Science and technology- Translational Medicine, Porto Alegre, Brazil
Towards an assessment tool for mixed depression: a multinational study using modified Hypomania Checklist (mHCL) in bipolar and unipolar depression K Altinbasa, A Ozerdemb,c N Yalinb, Z Ersoyb, O Aydemird, M Prietoe, S Oztekind, E Aydind,
M Fuentesf, S Feederf, MA Fryef
aRaşitTahsin Mood Clinic, Bakırköy Research and Training Hospital for Psychiatry,
Neurology and Neurosurgery,Istanbul,Turkey, bDepartment of Psychiatry, Faculty
of Medicine, Dokuz Eylul University, Izmir,Turkey, cDepartment of Neuroscience,
Health Sciences Institute; Dokuz Eylul University, Izmir,Turkey, dDepartment
of Psychiatry, Faculty of Medicine, Celal Bayar University, Manisa, Turkey,
eDepartment of Psychiatry, University of Los Andes, Santiago, Chile f Department
of Psychiatry, Mayo Clinic, Rochester, MN, USA
Monozygotic twins discordant for bipolar disorder show functional DNA methylation changes in whole blood and brain.
MPM Boksa,b, R Pidsleyc, K van Eijkd, EL Dempsterc, S de Jonge, L Schalkwijkc,
HE Hulshof-Polla, NEM van Harena, R Murrayc, RS Kahna, J Millc, RA Ophoffa,d aRudolf Magnus Institute of Neuroscience, Department of Psychiatry, University
Medical Center Utrecht, Utrecht, The Netherlands bJulius Center for Health
Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands, cInstitute of Psychiatry, King’s College London, United Kingdom, dDepartment of Medical Genetics, University Medical Center Utrecht, Utrecht,
The Netherlands, eUCLA Center for Neurobehavioral Genetics, Semel Institute for
Neuroscience and Human Behavior, Los Angeles, CA, USA
Day 2: Thursday, March 15, 2012
Suicidal behaviors in bipolar children: A community-based multisite investigation RC Castilla-Puentesa, WI Castilla-Puentesb, SR Castilla-Puentesc, IS Lopezd, A Camachoe,
ME Habeychf , CA Sanchez-Russig
aDepartments of Psychiatry, Epidemiology and Pharmacoepidemiology, at
the School of Medicine, UNC and at the School of Pharmacy, QA/RA, Temple University, Philadelphia, PA, bDepartment of Obstetrics and Gynecology, Hospital
Regional, Duitama, Boyaca, Colombia, cDepartment of Anesthesiology, Hospital
Regional, Duitama, Boyaca, Colombia, dDepartments of Psychiatry, Hospital San
Rafael,San Rafael, Mendoza, Argentina, eDepartment of Psychiatry, University of
California, San Diego; Sun Valley Behavioral & Research Center, CA, fCenter for
Clinical Neurophysiology, University of Pittsburgh, Pittsbrugh, PA, gDepartment of
Epidemiology and Public Health, INSA-Colombia, Boyaca, Colombia
The Illness Cognitions Scale: A new scale to measure maladaptive illness beliefs and behaviors that may impede recovery
S Dodda,b, M Berka,b,c,d, L Berkb, PB Fitzgeralde, AR de Castellae, S Filiae,K Filiae, AJM
Brnabicf, K Kelinf, W Montgomeryf, J Kulkarnie, L Staffordb,g
aSchool of Medicine, Deakin University, Geelong, Australia, bDepartment of
Psychiatry, University of Melbourne, Parkville, Australia, cOrygen Research
Centre, Parkville, Australia, dMental Health Research Institute, Parkville, Australia, eAlfred Psychiatry Research Centre, The Alfred and Monash University, School
of Psychology, Psychiatry and Psychological Medicine, Commercial Road, Melbourne, Australia, fEli Lilly Australia Pty Ltd, Sydney, Australia, gCentre for
Women’s Mental Health, Royal Women’s Hospital, Parkville, Australia QUESTION & ANSWERS
Day 2: Thursday, March 15, 2012
16:00 – 17: 30 PARALLEL 2 TOPKAPI B HALL
ISBD Women’s Health Task Force
Chairs: Aysegul Ozerdem, Dokuz Eylul University Medical School, Turkey Danilo Quiroz, Mood and Anxiety Center Efeso, Santiago, CHILI
Women are more vulnerable for Thyroid function abnormality in bipolar disorder Aysegul Ozerdem, Dokuz Eylul University Medical School, Turkey
How to be a Mother: Pregnancy and Breastfeeding Planning for Women with Bipolar Disorder
Fisun Akdeniz, Ege University School of Medicine, Turkey Childbirth and bipolar disorder: challenges and opportunities Verinder Sharma, University of Western Ontario, Canada
Brain derived neurotrophic factor in women with bipolar disorder compared to controls Natalie Rasgon, Stanford University School of Medicine, USA
QUESTION & ANSWERS
17:30 – 19:00 POSTER SESSION I FOYER - 1 ST FLOOR
17:30 – 20:30 TURKISH ADVOCACY FORUM MARMARA HALL
(Language: Turkish / No translation available)
19:00 – 20:30 EVENINg SYMPOSIUM ANADOLU AUDITORIUM
Sponsored by ASTRA ZENECA
“From Pole to Pole: Travelling to the Future”
Chair: Joseph Calabrese
Welcome and introduction
The neurobiology of affective disorders Ali Saffet gonul, Turkey
Developments in pharmacotherapy for depressive symptoms Lakshmi Yatham, Canada
Beyond pharmacotherapy Francesc Colom, Spain
Panel discussion
Summary and close All Chair
Day 3: Friday, March 16, 2012
08:00 – 09:30 CORE SYMPOSIUM 3 ANADOLU AUDITORIUM
Special Session on DSM-5 (ICD) Updates: Focus on Bipolar
Chair: David Kupfer
Update on Diagnostic Criteria for Bipolar Disorder
David Kupfer, University of Pittsburgh School of Medicine, USA The DSM-5 field trials and bipolar disorders
Ellen Frank, University of Pittsburgh School of Medicine, USA
09:30 – 10.30 KEYNOTE 3 ANADOLU AUDITORIUM
Bipolar Spectrum
Chair: gary Sachs, Massachusetts General Hospital, USA The Bipolar Spectrum: From temperament to genes
Hagop Akiskal, San Diego Veterans Administration Medical Center,Psychiatry
Service, USA QUESTION & ANSWERS 10:30 – 10:45 Coffee Break
10: 45 –12.15 CORE SYMPOSIUM 4 ANADOLU AUDITORIUM
Molecular genetics
Chairs: Charlie Nemeroff, University of Miami, USA
Luis Madrid Peroza, Centro Clínico Profesional Caracas, Venezuela Individual differences and evidence based psychopharmacology Robert Belmaker, Ben-Gurion University of the Negev, Israel
genetic Research into Bipolar Disorder
Marcella Rietschel; Heidelberg University/Medical Faculty Mannheim, Germany Prediction of Disease Vulnerability and Treatment Response in Mood Disorders: Personalized Medicine in Psychiatry
Charlie Nemeroff, University of Miami, USA
QUESTION & ANSWERS 12:15– 12:45 Lunch Break
Day 3: Friday, March 16, 2012
12:45 – 14:15 SATELLITE SYMPOSIUM ANADOLU AUDITORIUM
Sponsored by LUNDBECK
“Time to revisit the definition and treatment of bipolar I disorder in a Multidimensional way”
Chair: Michael Berk, Australia
Introduction By Michael Berk, Australia
The complexity of subsyndromal symptoms in the management of bipolar I disorder
Michael Berk, Australia
Asenapine and its multifunctional receptor profile: differentiation and clinical relevance
Mohammed Shahid, UK
Effective remission with asenapine treatment in patients with bipolar I disorder Andrea Fagiolini, Italy
Panel discussion QUESTION & ANSWERS 14:15 – 15:45 CONCURRENT SESSIONS III
14:15 – 15:45 SYMPOSIUM 5 MARMARA HALL
Psychosocial Treatments for Bipolar Disorder: Cross-Cultural Approaches
Chairs: Sibel Cakir, Istanbul University, Istanbul Medical School, Turkey Eric Youngstrom, University of North Carolina, USA
Cross-Cultural Insights into the Assessment and Treatment of Bipolar Disorder Eric Youngstrom, University of North Carolina, USA
Psychosocial Approach to Bipolar Disorders: Developing a Culture-Specific Model Sibel Cakir, Istanbul University, Istanbul Medical School, Turkey
The Effect of group Psychoeducation on the Korean Patients with Bipolar Seunghee Won, Kyungpook National University, School of Medicine, Daegu, Korea Psychosocial community approach for Bipolar Patients from Mexico
Manuel Sanchez de Carmona, ISBD Mexican Chapter, Mexico
QUESTION & ANSWERS
Day 3: Friday, March 16, 2012
14:15 – 15:45 SYMPOSIUM 6 TOPKAPI A HALL
Functional Consequences of Risk genes for Bipolar Disorder
Chairs: Carrie Bearden, University of California, Los Angeles, USA Carlos Lopez, Hospital Universitario San Vicente de Paul, Colombia
The effect of CACNA1C rs1006737 polymorphism on brain structure, function and connectivity in BD
Sophia Frangou, King’s College London, UK
Delineating the genetic Architecture of Bipolar Disorder with Neurocognitive, Neuroimaging and Transcriptional Endophenotypes
David glahn, Hartford Hospital, Yale University
Bipolar Endophenotypes in a genetically Isolated Population Carrie Bearden, University of California, Los Angeles, USA
QUESTION & ANSWERS
14:15 – 15:45 BREAKINg NEWS 2 DOLMABAHCE C HALL
(Oral Presentations)
Chair: Yeon Ho Joo, University Of Ulsan College Of Medicine, South Korea Sensitivity and specificity of the Mood Disorders Questionnaire as a screening for bipolar disorder during pregnancy and postpartum
BN Freya,b,c, W Simpsona,c, L Wright d, M Steinera,c
aWomen’s Health Concerns Clinic, St. Joseph’s Healthcare Hamilton; bMood Disorders
Program, Department of Psychiatry and Behavioural Neurosciences, McMaster University; cMiNDS Neuroscience Program, McMaster University; dPsychology
Neuroscience and Behaviour, McMaster University, Hamilton, ON, Canada
The effect of emotion regulation on cortico-limbic coupling in bipolar disorder and schizophrenia
RW Morrisa,b, A Sparksa,c, PB Mitchella,c, C Shannon Weickerta,b,d, MJ Greena,b,c.
aSchool of Psychiatry, University of New South Wales, Randwick, NSW, Australia; bSchizophrenia Research Institute, Darlinghurst, NSW, Australia; cBlack Dog Institute,
Prince of Wales Hospital, Randwick, NSW, Australia; dSchizophrenia Research Laboratory,
Day 3: Friday, March 16, 2012
Childhood maltreatment and physical health problems among people with bipolar disorder
gM Hosang, B Maughan, P Mcguffin, AE Farmer
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, De Crespigny Park, London SE5 8AF, United Kingdom
Personalized pharmacotherapy for bipolar disorder: genetic predictors of response to lithium
JR Kelsoea,b, SG Leckbanda,c, A Demodenaa,b, M McCarthya,b, T Shekhtmana,b
aDepartment of Psychiatry, University of California, San Diego, CA, USA, bDepartment of Psychiatry, VA San Diego Healthcare System, La Jolla, CA, USA, cDepartment of Pharmacy, VA San Diego Healthcare System, La Jolla, CA USA
Aberrant set points of the immune system in a Dutch bipolar offspring cohort - twelve year follow up
E Mesmanª, MHJ Hillegersª, WA Nolenb, HA Drexhagec
ªDepartment of Psychiatry, University Medical Centre Utrecht, Utrecht, The
Netherlands, bDepartment of Psychiatry, University Medical Centre Groningen,
University of Groningen, Groningen, The Netherlands, cDepartment of
Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands
Reduced inferior frontal gyrus activation during emotion inhibition in young people at increased genetic risk for bipolar disorder
PB Mitchella,b
,g Robertsa,b , MJ Greena,c, M Breakspeara,b,d,e, C McCormacka,b, A Franklanda,b,
A Wrighta,b, F Levya,f, R Lenroota,c, HN Chana,b,g
aSchool of Psychiatry, University of New South Wales, Randwick NSW, Australia, bBlack Dog Institute, Prince of Wales Hospital, Randwick NSW, Australia, cNeuroscience Research Australia, Randwick, NSW, Australia, dDivision of Mental
Health Research, Queensland Institute of Medical Research, Brisbane, Queensland, Australia, eRoyal Brisbane and Women’s Hospital, Brisbane, Queensland, Australia, fPrince of Wales Hospital, Randwick, NSW, Australia, gDepartment of Psychiatry,
Singapore General Hospital, Singapore. QUESTION & ANSWERS
Day 3: Friday, March 16, 2012
14:15 – 15:45 PARALLEL 3 TOPKAPI B HALL
Lithium
Chairs: Simavi Vahip, Ege University Medicine Faculty, Turkey Oscar Heeren Ramos, Peru
Lithium, still a major option in the management of bipolar disorder Rasmus Licht, Aarhus University Psychiatric Hospital, Denmark
Reasons to use lithium in bipolar disorders and obstacles in real world Simavi Vahip, Ege University Medicine Faculty, Turkey
Combination of Lithium with atypical Antipsychotics for long-term management of Bipolar Disorder
Carlo Altamura, University of Milan, Italy
QUESTION & ANSWERS 15:45 – 16:00 Coffee Break
16:00 – 17: 30 CONCURRENT SESSIONS IV
16:00 – 17: 30 SYMPOSIUM 7 MARMARA HALL
genomic and Clinical Phenotypic Considerations in Evaluating Antidepressant-Induced Mania to Individualize the Treatment for Bipolar Depression
Chairs: Mark A. Frye, Mayo Clinic, USA Shigenobu Kanba, Kyushu University, JAPAN
Clinical Correlates of Antidepressant – Induced Mania
Robert Post, MD, USA
A meta-analysis examining risk of switch following treatment with antidepressants in patients with bipolar depression
glenda MacQueen,University of Calgary, Calgary, AB, Canada
The Clinical Phenotype of Antidepressant-Induced Mania: Previous Methodologic Limitations and Recommendations for Future Studies
Mark A. Frye, Mayo Clinic, USA
Discussion
Thomas g. Schulze, Göttingen Georg-August-Universitä, Germany
