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High-Discrimination Factor Nanosensor Based on Tetrahedral DNA Nanostructures and Gold Nanoparticles for Detection of MiRNA-21 in Live Cells

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Figure

Figure 1. (A, B) Fluorescence kinetic curves of mutation base in the middle, distal or proximal site of the target and target detection by ExP and OrP, respectively
Figure 2. Structural characterization of Au-TDNNs. (A) PAGE analysis shows reduced electrophoretic mobility with the step-by-step assembly of TDNs
Figure 3. (A)100 nM and the fluorescence was collected at 520 nm. (C) The ability of Au-NPs@ExP1P2 and Au-NPs@OrP1P2 to distinguish point mutation target and target analogs were evaluated by DF
Figure 4. Enzymatic resistance of phosphorothioate-modified Au-TDNNs. (A, B) Fluorescence time graph depicting terminal-modified Au-TDNN and overall-modified Au-TDNN degradation by DNase I
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