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DQB1*0602 rather than DRB1*1501 confers susceptibility to multiple sclerosis-like disease induced by proteolipid protein (PLP)

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Figure

Figure 1 Preparation of recombinant hchromatography on Nipositions of the deleted hydrophobic domains
Table 1 List of the synthetic peptides spanning hPLPused in this study
Figure 2 Mapping immunogenic DR15- and DQ6-associatedml). Results expressed as stimulation index (S.I., mean cpm ofantigen containing cultures/mean c.p.m of medium-containingcultures) are from one experiment with pooled draining LNC fromtwo mice immunized
Figure 3 Epitope-specificity of hepitope for DRB1*1501 and/or DQB1*0602 molecule, but is not a major TCR or MHC binding residue, as predicted in silico: and **, depictspeptides containing Cys in the nonameric core epitope for DRB1*1501 and/or DQB1*0602 mol
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