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Evolution of the vertebrate claudin gene family: insights from a basal vertebrate, the sea lamprey

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Figure

Fig. 1. Analyis of the phylogenetic relationships among vertebrate claudins.  Maximum likelihood phylogenetic tree constructed using lamprey (Pm), Xenopus (Xt), chick (Gg) and mouse (Mm) claudin amino acid sequences
Fig. 2. Expression of claudins in lamprey adult and embryonic tis-sues. Analysis of claudin expression by RT-PCR in adult eye, gill, heart, liver and skin and at selected stages of embryonic development
TABLE 1
Fig. 5. Expression pattern of Claudin 9. Claudin 9 expression is seen in the neural tube (B-G1, C’, E’, E’’), otic placode/ear (B-I, G’), notochord (E-I, E’’), retina/eye spot (G1-I, G’), pronephros/kidney (E-H, E’’) and endostyle (H, I, I’).Staining on th
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