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Studies of synthetic chalcone derivatives as potential inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and pro-inflammatory cytokines

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Figure

Figure 1 synthesis of chalcone derivatives (i = naOh, ethanol).
Table 1 inhibition of secretory phospholipase a2-V (sPla2-V), cOX-1, cOX-2 and lOX-15 activities by synthetic chalcone derivatives
Figure 2 structures of models of cOX-2, phospholipase a2-V and templates.Notes: (A) showing model of phospholipase a2-V
Figure 3 amino acid sequence alignment for cOX-2.Abbreviation: cOX, cyclooxygenase.
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