What
IVFtech is a company producing advanced equipment for IVF laboratories.
The art and science of human assisted reproduction often demands individual solutions where strict considerations must be given to the culture conditions and the growth environment of gametes and embryos. Key factors for success rely on providing a steady temperature close to 37°C and secure an atmosphere with the right humidity and CO2-concentration.
Where
IVFtech started at the facilities at Trianglen Fertility Clinic, Denmark. Now the company has moved the production to bigger premises at Stenløse, Denmark.
All our products are manufactured in Denmark. We believe in high quality and close relationships with our customers and subcontractors.
When
Since 1977 we have cultured human gonadal tissues and germinal cells and developed culturing devices ever since. Experience from our daily work in the laboratory since 1977 has been the key to inspiration and innovation of the equipment we manufacture.
In short: We know how well our products work because we use them every day.
Who
IVFtech was founded in 1998 by Jørgen Grinsted, MD., DMSc. gynaecologist in collaboration with engineer Kjeld Nielsen and Professor MSc., DMSc. Claus Yding Andersen.
We are all affiliated to a research laboratory and a fertility clinic.
Product description ... 4
IVFtech Sterile ... 6
IVFtech sterile DS ... 12
Build your cabinet ... 14
IVFtech Class II ... 16
Closed system ... 18
Z-table, tubewarmer and flushing ... 20
Antivibration table ... 22
Heated tabletop ... 23
Mini incubator ... 24
Accessories ... 26
Heating pattern ... 27
SOLUTION FOR ASSISTED REPRODUCTION
Contents:
Worldwide delivery
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IVFtech Sterile is a vertical laminar flow, designed to give the best product
protection for IVF laboratories
IVFtech Class II giving operator and product protection.
Varmebænk
Komfur
Emhætte
Motorsav
Excellent sterile IVF cabinet
IVFtech Sterile is made to meet the requirements for IVF laboratories, such as “vitrification” cabinets “ICSI” cabinets, “sperm collection” cabinets, “routine work” cabinets.
Low noise level - <51 dB(A)
IVFtech Sterile has been designed to give you the lowest noice level on the market Filtration
Class H-14 HEPA filters in accordance with EN 1822. Filter efficiency 99.999% against 0.3 μm particle
size. 99.995% in MPPS. HEPA filters are protected by a carbon pre-filter for longer life. Size
90cm (3ft) 120cm (4ft) 150cm (5ft) 180cm (6ft)
Excellent Class II IVF cabinet
IVFtech Class II is made to meet the requirements for IVF laboratories, such as “vitrification” cabinets “sperm collection” cabinets, “routine work” cabinets.
Low noise level - <53 dB(A)
IVFtech Class II has been designed to give you the lowest noice level on the market Filtration
Class H-14 HEPA filters in accordance with EN 1822. Filter efficiency 99.999% against 0.3 μm particle
size. 99.995% in MPPS. Size 90cm (3ft) 120cm (4ft) 150cm (5ft) 180cm (6ft)
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IVFtech Sterile
Preparation for all brands
of microscopes
Heated tabletop
See pattern page 23
IVF Witness to be built
into IVFtech Sterile,
IVFtech Class II and
Unica
Build-in small incubator
at your choice
Built-in monitor
Outside monitor
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Anti-vibration table inside
cabinet
Heated glass ø45mm
UV light
New easy to use control
board with timer to switch
on/off the fan and or the
heated tabletop
Aspiration tunnel
Carbon prefilter for VOC
protection
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Model Unit 90 120 150 180
External dimensions (DxWxH) mm 690x1015x1245 690x1320x1245 690x1625x1245 690x1930x1245 Working chamber, dimensions mm 560x950x635 560x1235x635 560x1560x635 560x1865x635 (DxWxH)
Front opening, fixed mm 350 350 350 350 Support Stand, height standard mm 850-950 850-950 850-950 850-950 Air velocity, Vertical flow m/s 0,34 0,34 0,34 0,34 Air velocity, deviation ±% 8 8 8 8 Flow rate m3/h 775 1050 1250 1450 Noise level; ISO 6081 dB(A) <51 <51 <51 <51 Light variable up/down Yes Yes Yes Yes HEPA fliters H-14 H-14 H-14 H-14 Voltage/frequency V/Hz 230/50 230/50 230/50 230/50 Power cabinet/heated tabletop W 150/450 150/450 200/450 300/450 Fuses A 8 8 10 10 Net weight kg 140 150 180 190 Shipping volume m3 2,0 2,0 2,5 2,5
Designregistred Hi-MACS
®
table-tops MEA tested
The cabinet with Hi-Macs table-top is an unique product from IVFtech designed especially for IVFunique product from IVFtech designed especially for IVF market.
The advantages of Hi-Macs table-tops are:
1) The Hi-macs table-top are impact-resistant, scratch-resistant and wear-resistant.
2) Hi-macs gives a warm feel with non-porous, smooth surface that meets the most exacting hygiene requirements.
3) It has flexibility and the possibility of seamless joints together with ease of repairability. 4) Hi-macs products provides different color varieties for clients to choose.
Independent triple heated areas
HI-MACS® is the Solid Surface material of the “New Generation”. The mineral material consists of approximately one third acrylic resin (PMMA) and 5% natural pigments. Its main constituent, with 70%, is the natural mine-ral aluminium hydroxide (ATH) obtained from bauxite (aluminium ore).
Thanks to its modern processing technology HI-MACS® has:
• Improved impact strength • Enhanced scratch resistance • Better UV resistance
• Improved thermoplastic mouldability • A more homogeneous quality
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25.6
25.6
IVFtech sterile DS
IVFtech Light
IVFtech Sterile DS double sided cabinet is designed to be placed in the middle of the room.
It is possible to instal up to 4 heated working areas with stereo
microscopes and 2 extra small heated areas in the middle all independently controlled.Tabletop 1850mm x 1000mm is available in stainless or Hi-MACS® .
IVFtech Sterile Light is a new serie, which have a 0,6 m and 1,2 m cabinet.
A class A cabinet with only full speed and on/off light (non ajustable).
IVFtech Light is a standard cabinet. Options:
0,6 m is available with one heated area and preparation for microscope or as a cold cabi-net.
1,2 m is available with one heated area and preparation for microscope in right side, or as a cold cabinet.
IVFtech Light is available with wheels, easy to move around for use in different labs. Like all our other cabinets IVFtech Light can also be with adjustable electrical stand or fixed stand.
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Cabinet
Heating
Microscope
Heated glass
Gas
Built-in...
Stand
Accessories
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IVFtech Class II giving operator and product protection.
IVFtech Class II
Model Unit 90 120 150 180
External dimensions (DxWxH) mm 795x1015x1385 795x1320x1385 795x1625x1385 795x1930x1385 Working chamber, dimensions mm 655x945x670 655x1250x670 655x1555x670 655x1860x670 (DxWxH)
Front opening, fixed mm 200 200 200 200 Support Stand, height standard mm 850-950 850-950 850-950 850-950 Air velocity, Vertical flow m/s 0,31 0,31 0,31 0,31 Air velosity, deviation ±% 10 10 10 10 Flow rate m3/h 710 1000 1100 1300 Exhaust Flow rate m3/h 300 400 500 600 Noise level; ISO 6081 dB(A) <53 <53 <54 <54 Light variable up/down Yes Yes Yes Yes HEPA fliters H-14 H-14 H-14 H-14 Voltage/frequency V/Hz 230/50 230/50 230/50 230/50 Power W 600 600 700 800 Fuses A 10 10 10 10 Net weight kg 225 250 275 300 Shipping volume m3 2,2 2,2 2,5 2,5
IVFtech Class II is made to meet the requirements for IVF laboratories, such as “vitrification” cabinets “ICSI” cabinets, “sperm collection” cabinets, “routine work” cabinets.
New easy to use control board with timer to switch on/of the fan and on/off the heated tabletop. All brands of microscope can be installed, choice between oculares through the front window or a secondary window inside the cabinet, which allows the front window to be closed.
Options for Class II:
Stainless steel or Himacs® tabel top
Heated tabletop Flow meter Monitor outside
IVFtech heated glass Ø45mm UV light
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Semi closed system
A careful gamete and embryo manipulation has always been a key element of laboratory embryology and has contributed sub-stantially to the success of many assisted reproduction procedu-res.
Suboptimal in vitro conditions may both distress the competence to develop in vitro and lead to irreversible long-term alterations in the characteristics of the foetal and post natal growth. There-fore caution should be taken in the handling and manipulation of the oocytes and early embryos in order to achieve a stable biological optimal atmosphere, which creates optimal conditions for embryo growth.
The employment of IVF controlled-atmosphere workstation has been proposed in order to meet the special requirements of oo-cyte and embryo handling during IVF daily routine.
This self-contained chamber reproduces the incubator conditi-ons allowing the embryologists to perform oocytes and embryos manipulations while minimizing even slight alterations of the en-vironmental conditions (temperature changes, gas composition, culture medium osmolarity and pH) and preserving the embryo developmental potential.
Unica characteristics:
Double Temperature control: working area and tabletop. Ambient +5° up to 45° C
CO2 air control: 2,0% - 15,0% in the working
area.
HEPA and VOC filters to guarantee the decon-tamination of the air in the chamber
Ideal level of humidity.
Suitable with stereomicroscope like Leica, Ni-kon, Olympus and Zeiss.
Touch Screen Control Software to register and monitor the data.
Alarms: visual and audible for temperature and
CO2
Built-in monitor
IVFtech Unica
Closed system dimensions:
External dimension: w x d x h mm: 1015 x 680 x 1750 Working chamber: w x d x h mm: 990 x 430 x 480 Electrical stand (optional)
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IVFtech Z-table
Accessories
IVFtech Z-tables:
Heated tabletop with wheels in either white Hi-MACS or stainless steel. All tables comes with a draw, choose between heated drawer or non heated drawer.
Order no.
2501265 Z-table:
on weels with heated drawer, stainless steel 2501266 Z-table:
on weels with heated drawer, Hi-MACS 2501267 Z-table:
on weels without heated drawer, stainless steel
2501268 Z-table:
on weels without heated drawer, Hi-MACS Dimensions (cm): W:10 D:20 H:13,5 Heater power: 40W Setpoint: Ambient to 50° C (higher on request) Order no.: 2503165
IVFtech tubewarmer fits 14 test tubes 14ml. Temperature easy to change.
Removeable sides for easy cleaning.
Aluminium block covers 2/3 of the tube which gives better uniform heat to the tubes.
IVFtech flushing machine with footpedal for Follicular flushing during oocyte retrieval Part no. 2503166
Weight 7,5kg
Power supply: 220-240VAC
Syringe capasity: 1 x 50ml Syringe Temperature setting: Ambient to 50° C Volume and flow
Low speed
step1: 1ml/step - 1ml/second step 2: 2ml/step - 1ml/second step 3: 4ml/step - 1ml/second High speed
step 4: 2ml/step - 2ml/second step 5: 3ml/step - 2ml/second step 6: 4ml/step - 2ml/second
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Anti-vibration table
Heated tabletop with built-in microscope
For ICSI procedures
IVFtech Anti-vibration table are designed to meet the requirements for all avaible models of inverted microscopes. The antivibration works on air.
The tabletop is made of Hi-MACS (Grey or White)
Standard size w x d x h: 1150 mm x 720 mm x 790-830 mm
Heated tabletop
IVFtech Heated tabletop can be supplied with or without microscope and with or without wheels. Electrical or water heated.
Standard sizes 900 mm, 1200 mm, 1500 mm, 1800 mm.
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IVFtech Mini-incubator
Operating the airtight mini-incubator is straightforward. The incubator is placed on the flowbench and the valve at the back of the incubator is used to connect to the gas-outlet via snap-lock.
Four-well dishes or round culture dishes with gametes are placed on the shelves. With the lid loosely closed a gas flow for around 3 minutes will secure the correct atmosphere in the incubator.
By closing the lid and releasing the snap-lock the atmosphere will remain constant in the incubator until the lid is opened. The incubator can now be moved to the main incubator, where disturbances in the atmosphere will not be reflected in the mini-incubator.
Culturing at low oxygen tension
Metode: By securing an atmosphere with reduced oxygen tension, the oxygen concentration in the media around the oocytes/embryos is reduced.
A reduced oxygen stress may possibly improve the embryos implantation potential.
Procedure: 1. The airtight mini-incubator is placed on top of the heated surface in the flow cabinet and is connected to the gas via the valve on the back.
2. Gas through the box for 3 minutes with the lid loosely closed. 3. After 3 minutes firmly close the lid and remove the gas supply
4. After inspection for fertilization on day 1, put the petridish with the embryos back in the boxmini-incubator, and then gas it for 3 minutes with the lid loosely closed.
5. After 3 minutes firmly close the lid and remove the gas supply. Seal the box by turning the knop.
6. The box is moved to the incubator for the next 24 hours. Step 4 and 5 are repeated on day 2 of culturing period or until embryo transfer is performed.
This mini incubator is 1. All non-toxic aluminium
2. Airtight, but allows equilibration with a desired atmosphere 3. Support three 4-well dishes or three 60 mm round culture dishes 4. Allow inspection of gametes while situated in the incubator shells 5. Sustain autoclaving.
It is an ideal solution for:
1. Maintain a constant pH in the medium surrounding the gametes in a busy every day IVF-lab
2. Maintain a constant atmosphere – similar or different to that of the mother incubator
3. Maintain a constant humidity and thereby osmolality of the medium. 4. Reduce the risk of cross patient contamination
5. Maintain temperature close to 37 degrees also during handling. 6. Fast identifi cation of gametes and embryos in the mother incubator limiting the time that the door being open.
7. Minimize exposure of gametes and embryos to light.
100mm
100mm
Operating the IVFtech mini-incubator
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900 (1015 mm) 1200 (1320 mm) 1500 (1625 mm) 1800 (1930 mm) 2185 mm 795 mm
IVF Class II
Water heated
Electrical heated
700 mm 500 mm 900 mm 1200 mm 1500 mm 1800 mm 650 mm 450 mm 900 mm 1200 mm 1500 mm 1800 mm 900 (1015 mm) 1200 (1320 mm) 1500 (1625 mm) 1800 (1930 mm) 2045 mm 690 mmIVF Sterile
IVFtech accessories
Warming blocks
for small and larger test tubes: 14/17 cc or 6 cc.
Warming blocks for petri dishes and mediaflask
Warming blocks may be used to secure the temperature in the plastic dish while used at the temperated tabletop.
Glass hood
for CO2 flow to the culture
dishes which are to be used to equilibrate the culture medium.
Glass bubble flask
The gas bobble flask humidifies the 5% CO2 gas mixture before use.The
humidified gas is used for conditioning the IVF culture media and as gas flow source in connection with oocyte aspiration or embryo transfer.
