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KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance

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Figure

Figure 1. (a-b) The viability of cells treated with cisplatin 24h in concentrations as indicated was determined CCK-8 assay
Figure 2. (a) Immunofluorescence staining determined XRCC1and γH2AX foci by exposure of SGC7901/DDP cells to 5μg/ml cisplatin and 10μM JIB-04 for 24h (×1000)
Figure 3. (a) Western blotting determined the expression of KDM5B in each cell as indicated
Figure 4. (a) The peptide of HSP90 was detected by Mass spectrometry. (b) immunoprecipitation determined the interaction of flag-KDM5B (flag-tag) and HSP90 in SGC7901 cells treated with 1μg/ml cisplatin for 24h
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