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E3 ubiquitin ligase Pirh2 enhances tumorigenic properties of human non-small cell lung carcinoma cells

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Figure

Figure 1: Pirh2 affects proliferation of H1299 cells. (А) Evaluation of transduction efficiency of H1299 cells with LeGO- and LeGO-Pirh2 by FACs analysis of GFP-positive cells
Figure 2: Pirh2 enhances the migratory potential of H1299 cells. (А) The migratory activity of H1299 LeGO-Pirh2 cells and control H1299 LeGO cells shown as cell index graphs
Figure 3: Pirh2 affects the resistance of H1299 cells to doxorubicin. (A) Cell index graphs obtained for H1299 cells stably expressing LeGO-Pirh2, control LeGO, Pirh2 shRNA, and scrambled shRNA, respectively, which were exposed to 1 μM doxorubicin
Figure 4: Effect of Pirh2 on colony formation and apoptosis of H1299 cells treated with doxorubicin
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