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Uncovering interaction by QbD in Optimization of Stability-indicating HPLC Method for Simultaneous Estimation of Low Dose Aspirin and Lansoprazole

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Figure

Fig. 1: Structure of ASP and LAN.(A) Structure of aspirin (ASP) and (B) lansoprazole (LAN).
TABLE 2: EXPERIMENTAL RUNS FOR BBD
Fig. 2: Chromatograms of the developed method.(a) Initial chromatogram, (b) optimized chromatogram, (c) chromatogram of formulation with blank, (d) peak purity curve of ASP and LAN
Fig. 4: 3D surface contour plots.(a) 3D surface plots for resolution 1; (b) 3D surface plots for resolution 2; (c) 3D surface plots for resolution 3; (d) 3D surface plots for retention time 4.
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