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Development and Validation of a HPLC-based Bioanalytical Method for Lorcaserin using Solid Phase Extraction and Application to a Pharmacokinetic Study in Rats

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Figure

TABLE 1: CHROMATOGRAPHY TRIALS FOR INTERNAL STANDARD SELECTION
TABLE 2: SUMMARY OF VALIDATION AND SYSTEM SUITABILITY TEST PARAMETERS
Fig. 2: HPLC chromatograms Chromatogram of analyte and internal standard spiked in human plasma (A); chromatogram of blank unspiked rat plasma sample (B); chromatogram of extracted sample at time interval of 60 min after administration of the drug
TABLE 5: PHARMACOKINETIC PARAMETERS FOR BIOANALYTICAL METHOD

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