Synthesis, characterization and biological activity of 1,6,7 triazaspirothiazolidine,tetrazoles and azetidines
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![Table 1: Mass spectral data of primary fragmented ions for 3-chloro-6-(2,5-difluorobenzoyl)-8-(4-oxo-2-phenylthiazolidin-3-yl)-1-((4-(trifluoromethyl)phenylamino)-1,6,7-triazaspiro[3.4]oct-7-ene-2,5-dione (10a)](https://thumb-us.123doks.com/thumbv2/123dok_us/8776181.901575/5.595.96.519.526.740/spectral-primary-fragmented-difluorobenzoyl-phenylthiazolidin-trifluoromethyl-phenylamino-triazaspiro.webp)
![Table 4: Mass spectral data of secondary fragmented ions for 3-chloro-6-(2,5-difluorobenzoyl)-8-(5-phenyl-1H-tetrazol-1-yl)-1-((4-(trifluoromethyl)phenylamino)-1,6,7-triazaspiro[3.4]oct-7-ene-2,5-dione (11a)](https://thumb-us.123doks.com/thumbv2/123dok_us/8776181.901575/7.595.142.471.512.727/spectral-secondary-fragmented-difluorobenzoyl-tetrazol-trifluoromethyl-phenylamino-triazaspiro.webp)
![Table-7 Determination of zone of inhibition (in mm) of 3-chloro-6-(2,5-difluorobenzoyl)-8-(2-(4-substituted phenyl)-4-oxothiazolidin-3-yl)-1-((4-(trifluoromethyl)phenyl)amino)-1,6,7-triazaspiro[3.4]oct-7-ene-2,5-dione (10 a-f),) (µg/mL)](https://thumb-us.123doks.com/thumbv2/123dok_us/8776181.901575/10.595.137.474.98.403/determination-inhibition-difluorobenzoyl-substituted-oxothiazolidin-trifluoromethyl-phenyl-triazaspiro.webp)
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