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Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice

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Academic year: 2020

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Figure

Figure 1
Figure 2LDLR expression in
Figure 3Effect of the mTOR inhibitor rapamycin on LDLR expression. (A) Immunoblot analysis of LDLR, p-S6KT389, total S6K, PCSK9, and β-actin in mice treated with rapamycin
Figure 4HNF1α is involved in the regulation of LDLR by insulin signaling. (A and B) Immunoblot and real-time qPCR analysis of HNF1α in InsR- or scrambled shRNA–injected mice and vehicle- or rapamycin-treated mice
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