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Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development

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Figure

Fig. 1. Lymphatic vessels show remodeling defects in Sdc4−/− mice during late embryonic development
Fig. 2. Abnormal alignment of actinfilaments and compromised formation ofremaining parallel to the flow direction areconsidered as abnormal valves
Fig. 3. Pecam1of nuclei reoriented >45° relative to flow direction is indicated. MannProx1−/− mice show lymphatic remodeling defects at E18.5
Fig. 4. Disorganized actin stress fibers andreduced formation of mature lymphaticrepresent mean±s.e.m
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