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Deciphering the mechanism of Indirubin and its derivatives in the inhibition of Imatinib resistance using a “drug target prediction gene microarray analysis protein network construction” strategy

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Figure

Table 1 Indirubin and 41 derivatives and putative targets
Fig. 1 Based on GEO2R analysis, differentially expressed genes of imatinib resistance in chronic myeloid leukemia were Identified from GEO2810(logFC> 1 or logFC < − 1;P < 0.05), and a P-P network about DEGswas constructed
Table 2 The top 10 significantly up-regulated DEGs and down-regulated DEGs
Fig. 2 The significantly up-regulated GO categories and enrichment pathways of DEGs(P < 0.05)
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