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Direct crossregulation between retinoic acid receptor β and Hox genes during hindbrain segmentation

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Fig. 1. Rarb is expressed more anteriorly than Hoxb4 in thepresegmented hindbrain. The anterior neural expression borders ofHoxb4 protein (A,C,E) and Rarb mRNA (B,D,F) are compared atE8.5 and E9.5
Fig. 2C,D) it is likely that, as yet uncharacterized, post-transcriptional Hox-regulatory mechanisms are involved(Brend et al., 2003; Dasen et al., 2003).
Fig. 4. The activity of the proximal enhancer is largely confined to thedeveloping spinal cord with only residual low levels remainingwithin the caudal hindbrain
Fig. 4B). One day later, at E9.5, proximal enhancer activity hasregressed dramatically and is now missing from most of thecaudal hindbrain but remains present in the spinal cord (Fig.
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