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Volume 31, January-June 1968

Journal of the American College

of Obstetricians and Gynecologists

S. Leon Israel, M.D., Philadelphia, Editor

Ralph A. Reis, M.D., Chicago, Emeritus Editor

EDITORIAL BOARD

Clayton T. Beecham, M.D., Danville, Pa.

Richard L. Burt, M.D., Winston-Salem, N. C.

Charles A. Hunter, Jr., M.D., Seattle, Wash.

John Figgis Jewett, M.D., Boston, Mass.

Robert A. H. Kinch, M.D., London, Ont.

Richard F. Mattingly, M.D., Milwaukee, Wis.

J. George Moore, M.D., New York, N.Y.

Jack A. Pritchard, M.pD., Dallas, Tex.

Published Monthly by Hoeber Medical Division « Harper & Row, New York

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Copyright © 1968 by

THE AMERICAN COLLEGE OF OBSTETRICIANS AND GYNECOLOGISTS

All rights reserved. For information address (

HOEBER MEDICAL DIVISION © HARPER & ROW, PUBLISHERS 49 East 33rd Street, New York, N. Y. 10016

Printed in the United States of America

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Contents

JANUARY Megaloblastic Anemia of Pregnancy

ASAD U, KHAN, RAYMOND W. MONTO, and LEE B. STEVENSON

Villous Immaturity in the Term Placenta H. FOX

Virilizing Lipoid Cell Tumor of the Ovary: Report of 2 cases, 1 with uterine hypertrophy KARL R. MEYERS, LIVIA S. WAN, RONALD J. BOLOGNESE, and HOWARD BALIN Carcinosarcoma and Mixed Mesodermal Tumor of the Ovary: A clinicopathologic analy-

sis of 9 cases BERNARD CZERNOBILSKY and GARY C. LA BARRE Proliferative Stromatosis of the Uterus with Pulmonary Metastases: Remission following

treatment with a long-acting synthetic progestin: A case report DOMINIC PELLILLO Meigs-like Syndrome Secondary to Krukenberg’s Tumor

WILLIAM E. BRENNER and ROGER B. SCOTT Theca Cell Tumor Associated with Pregnancy: Report of a case

A. TALERMAN and E. M. JAMES Simultaneous Extra- and Intrauterine Pregnancy: Report of a case

ANN B. BARNES, JOHN W. GROVER, and S. SCOTT SUDDUTH XO/XX/XY Mosaicism in a Female with Turner’s Syndrome

THOMAS S. MC CONNELL, CALVIN N. LADNER, and MARIA PFOERTNER Respiratory Effects of Alphaprodine in Man

WILLIAM H. FORREST, JR., and J. WELDON BELLVILLE Eclampsia Superimposed on Renal Scleroderma: A Rare Cause of Maternal and Fetal

Mortality ROBERT E. FEAR

Malignant Melanoma of the Female Urethra Treated by Cryosurgery with Radical Vul- vectomy and Anterior Exenteration: Report of a case

DONALD R. OSTERGARD and DUANE E. TOWNSEND Diabetes Insipidus Associated with Pregnancy: Report of a case

CHARLES O. STEPHENS and OSCAR J. HAYES Postoperative Adnexal Infections

WILLIAM J, LEDGER, COLIN CAMPBELL, and J. ROBERT WILLSON Aortoiliac Compression by Uterus Containing Hydrocephalic Fetus

J. BIENIARZ, L. GULIN, I. C. ARNT, T. HASHIMOTO, V. SAGUIER, and R. CALDEYRO-BARCIA Improved Fetal Salvage after Metroplasty

VINCENT J. CAPRARO, JUSTIN T. CHUANG, and CLYDE L. RANDALL Primary Omental Pregnancy: 2 cases of primary peritoneal pregnancy

MARY ANNA FRIEDERICH Induction of Ovulation by Combined Administration of Human Menopausal Gonado-

tropins and Clomiphene Citrate E. RABAU, S. MASHIACH, D. M. SERR, and H. MELMED Levels of Plasma Human Growth Hormone During Administration of Human Meno-

pausal Gonadotropin and Human Chorionic Gonadotropin JOHN A. BOARD Continuous Tablet Therapy for Oral Contraception

PHILIP J. DI SAIA, CLARENCE D. DAVIS, and BEN Z. TABER Intrauterine Hypothermia in the Management of Uterine Hemorrhage: Report of 2 cases

LAWRENCE L. TRETBAR and HOWARD P. TAYLOR Nonpuerperal Vaginitis Emphysematosa

JOSEPH A. DAINO, RENE J. GIRERD, and VICTOR TCHERTKOFF

13 21 33

45 50 53

61 69

75 79 83

97 104 110 116 119 125 128

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CONTENTS

Determining the Location of Intrauterine Devices with the Beolocator

SUWANEE RIMDUSIT and DANIEL R. MISHELL, JR.

Instrument & Method: Postpartum IUD Insertion with a Modified Lippes Inserter

W. G. POVEY Views and Reviews: Effects of Obstetric Hospitalization Policy upon Obstetric Mortality:

A Survey of 4133 Hospitals JOHN I. BREWER

Editorial: Obstetricians Should Learn the Technic of Amniocentesis HENRY A. THIEDE Book Reviews

FEBRUARY Organ Culture of Trophoblast

ALBERT B. GERBIE, HARVEY R. HATHAWAY, aiid JOHN I. BREWER Gonadal Hypoplasia Associated with Ring Chromosomes: Report of 2 cases

J. LASZLO, G. GYGRY, and G. SZILAGYI Bleeding from the Uterus Caused by Chloroma: Report of a case CHARLES E. HARTFORD Lymphocyte Transformation in Mixed Wife-Husband Leukocyte Cultures in Abortions

and in Hydatidiform Moles I. HALBRECHT and L. KOMLOS

Comparative Morphometry of the Human Placenta at High Altitude and at Sea Level:

I. The shape of the placenta

ALVARO CHABES, JOSE PEREDA, LYON HYAMS, NICOLAS BARRIENTOS,

JAIME PEREZ, LUIS CAMPOS, ADOLFO MONROE, and AMERICO MAYORGA Hypertriglyceridemia During Treatment with Estrogen and Oral Contraceptives: An

alteration in hepatic function?

HERBERT GERSHBERG, MILDRED HULSE, and ZENAIDA JAVIER Reversible “Cancer” and the Contraceptive Pill: Report of a case

JOHN GRAHAM, RUTH GRAHAM, and KOJI HIRABAYASHI The Diagnosis of Cervical Cancer During Pregnancy

MICHAEL R. SMITH, DAVID C. FIGGE, and JAMES L. BENNINGTON Decreasing the Morbidity of Vaginal Hysterectomy HENRI E. CHEHAB Septic Shock Following Vaginal Hysterectomy MYRON GORDON and ARTHUR HOROWITZ Ureteral Carcinoma as a Gynecologic Problem: Report of a case

FRANK C, KING, HUGH R. K. BARBER, and ALEXANDER BRUNSCHWIG Ciliated Epithelia of the Human Uterine Mucosa EDMUND F. SCHUELLER Maternal Risk in Abruption ROBERT G. BRAME, GUY M. HARBERT, JR., H. S. MC GAUGHEY, JR., and W. N. THORNTON, JR.

Gestational Diabetes SAMUEL G. SMITH and WILLIAM H. SCRAGG, JR.

Volume Changes in Amniotic Fluid Following Intra-amniotic Saline Injection

R. C. GOODLIN, A. J. KRESCH, and W. H. NORTHWAY LDH Activity in Patients with Ovarian Tumors

KRYSTYNA WIDY-KIERSKA and IRENEUSZ ROSZKOWSKI Lymphography with Chlorophyll: Effects on Pelvic Lymphadenectomy and Lymph

Nodes H. E. AVERETTE and R. RAVEL

Iatrogenic Arteriovenous Sinus of a Uterine Artery and Vein: Report of a case

LEONARD R. HOWARD Gonorrhea During Pregnancy GARY W. KRAUS and SAMUEL S. C. YEN Colon Hernia Through a Hiatus in the Broad Ligament: Report of a case and review of

the literature SANFORD E. RABUSHKA

Gynecologic Manifestations of Reticulum Cell Sarcoma

FAWZI A. ILIYA, FRANCO M. MUGGIA, JAMES A. O'LEARY, and THEODORE M. KING

Surgically Induced Urinary Incontinence GEORGE W. MORLEY

Successful Pregnancy with McGovern Aortic Prosthesis and Long-Term Heparin Ther- apy: Report of a case W. N. OTTERSON, GEORGE MC GRANAHAN, and M. V. R. FREEMAN

132 136 138 146 149

151 157 166 173

178

186 190 193 198 208 211 215 224 228 240 243 247 255 258 261 266 270 273

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CONTENTS

The Quality of Reproduction in an Urban Indigent Population: I. Birth weight: The differences between mothers of low-weight and of term-size infants

MARVIN ROSEN, ELINOR F. DOWNS, F. DONALD NAPOLITANI, and DONALD P, SWARTZ Views and Reviews: Low Birth Weight Infants JAN SCHNEIDER Editorial: Some Aspects of Carcinoma In Situ of the Uterine Cervix Vv. N. DEMIN Instrument & Method: A New Device for Endocervical Aspiration

DONALD H. KARIHER and THOMAS W. SMITH Letters

Book Reviews

MARCH

Laparoscopy: A Valuable Aid in Gynecologic Diagnosis ROBERT E. FEAR

Culdoscopy vs. Peritoneoscopy MELVIN R. COHEN

Critical Illnesses and Deaths Associated with Intrauterine Devices ROGER B. SCOTT Vasa Previa, Antepartum Diagnosis: Report of a case

CHARLES W. CURL and WAYNE L. JOHNSON Coexisting Metastatic Choriocarcinoma and Normal Pregnancy: Therapy during gesta-

tion with maternal remission and fetal survival

JAMES R, HUTCHISON, EDWIN P. PETERSON, and EDWARD A. ZIMMERMAN Surgical Excision of Pelvic Arteriovenous Fistula Following Successful Treatment of

Chorionepithelioma ROBERT W. LEIBOLD, F. J. KEEFER, and J. L. CURRY Critical Review of 160 Clomiphene-related Pregnancies

ALVIN F. GOLDFARB, ANTONIO MORALES, ABRAHAM E. RAKOFF, and PETER PROTOS Influence of Maternal Estrogen on Fetal Bone Development in the Rabbit

RAJA W. ABDUL-KARIM, JOHN T. PRIOR, and ROBERT E. L. NESBITT, JR.

Sedimentation Rates of Vaginal Cells: A simple screening technic for cervical cancer RUTH M. GRAHAM, MICHAEL M. GRAHAM, and JOHN B. GRAHAM Unilateral Tubal Triplet Pregnancy: Report of a case

DONALD A. FORBES and AGOSTINO NATALE Circular Prolapse of the Urethra in Children: A Cause of Vaginal Bleeding

JOHN M. ESPOSITO Norgestrel and Ethynyl Esiradiol: A new low-dosage oral agent for fertility control

EDRIS RICE-WRAY, CRISTINA AVILA, and JUVENAL GUTIERREZ Biliary Stasis after Mestranol-Norethindrone Ingestion: Report of a case

G. H. SABEL and R. F. KIRK Adrenal-Pituitary Responsiveness During Therapy with an Oral Contraceptive

JORGE H. MESTMAN, GAIL V. ANDERSON, and DON H. NELSON The Oversuppression Syndrome

BENSON J. HOROWITZ, MARK SOLOMKIN, and STANLEY W. EDELSTEIN Spectrophotometric,Analysis of Amniotic Fluid in Rh-Negative Women

WILLIAM POMERANCE, ARNOLD MOLTZ, JERZY J. BIEZENSKI, and LEWIS WOLF Amniotic Fluid pH as an Indicator of Fetal Asphyxia

STEPHEN CORSON ard RONALD J. BOLOGNESE Air Embolism: A discussion of maternal mortality with a report of 1 survivor

MARVIN D. SILVER and TOMMY N. EVANS Peivic Congestion: Some further considerations

HOWARD J. OSOFSKY and SEYMOUR FISHER Symptomatic Angiomyolipoma Associated with Pregnancy: Report of a case

ROBERT C. DRIPS, GEORGE J. TAYLOR III, MARTIN J. VALASKE, and MALCOLM L. COWEN

276 283 288 293 295 296

297 310 322 328

331 337

342 346 354 360 363 368 375 378 387

390 397 403 406

411

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CONTENTS

Relationship of Weight Gain During Pregnancy to Birth Weight and Infant Growth a and Development in the First Year of Life: A report from the collaborative study of cerebral palsy

JUDITH E, SINGER, MILTON WESTPHAL, and KENNETH NISWANDER Isoenzyme Patterns of Serum Alkaline Phosphatase in

Abnormal Uterine Bleeding BERNARD LEVINE, DAVID LIPSCHUTZ, JOEL BERNSTEIN, and CYNTHIA NEWMAN Instrument & Method: A New Instrument for Salpingostomy RYUJI YAMAGUCHI Views and Reviews: To Cone or Not To Cone—The Cervix

WILLIAM P. SINGLETON and FELIX RUTLEDGE After Office Hours: Some Social-Psychologic Issues in Improving Obstetric

Care for the Poor HOWARD J. OSOFSKY

Book Reviews

APRIL

Infectious Hepatitis and Pregnancy IVAN A. D’CRUZ, S. G. BALANI, and L. S. IYER Ophthalmologic Findings with Oral Contraceptives

ELIZABETH B. CONNELL arid CHARLES D. KELMAN Maternal Osteogenesis Imperfecta BRUCE K. YOUNG and FRED GORSTEIN Massive Intraperitoneal Hemorrhage from a Corpus Luteum Hematoma in Women

Taking Anticoagulants: Report of 2 cases ROBERT M. DACUS III Comparison of Standard Oral and Rapid Intravenous Glucose Tolerance Tests

in Pregnancy DUDLEY P. BAKER, JAMES R. HUTCHISON, and DANIEL L. VAUGHN Effect of an Ovulatory Suppressant on Glucose Tolerance and Insulin Secretion

F, XAVIER PI-SUNYER and STUART OSTER Endometrium with Pattern of Mesonephroma: Report of a case ROBERT E. FECHNER Erythrocyte Hemolysis and Fibrination-Fibrinolysis During Retained Abruptio

Placentae with Hypovolemia and Transient Anuria CHARLES L. SCHNEIDER Abruptio Placentae Early in Pregnancy S. L. NAOR and M. RIKOVER Acute Pancreatitis in Pregnancy: Report of 2 cases with maternal survival

ROBERT N. RABKIN Paget’s Disease of the Vulva: Report of 10 cases

LEOPOLD G. KOSS, SAKIKO LADINSKY, and ALFRED BROCKUNIER, JR.

Maternal Urinary Estriol Excretion after Dehydroepiandrosterone-Sulfate Infusion and Adrenal Stimulation and Suppression

ANTONIO SCOMMEGNA, BERTRAND R. NEDOSS, and SATI C. CHATTORAJ Multipolar Registration of the Fetal Electrocardiogram: Technic and Comparison

with Bipolar Method J. L. M. GIELEN, A. L. C. SCHMIDT, and P. H. MEGENS Estimation of Red Cell Volume Requirements for Intrauterine Transfusion:

Comparison of calculated and actual results in fetuses given 19 transfusions

VICTOR HALITSKY and BURTON A. KRUMHOLZ Clinical Significance of Placental Hemangiomas

LEON A. ASADOURIAN and HERBERT B. TAYLOR Editorial: The Story of Oral Contraceptives

HENRY S. ACKEN, JR., ROBERT C. ARRANTS, ALVIN F. GOLDFARB, JOHN S. LYLE, and FRANCIS B. O'BRIEN Views and Reviews: Dysgerminoma: A Clinical Review

JERRY A. WIDER and JAMES A. O'LEARY After Office Hours: The Making of a Woman's Hospital HOWARD C. TAYLOR, JR.

Abstracts: Reports on Current Investigation Letters

417

424 429 430 437 444

449 456 461 471 475 482 485 491 505 508 513

526 534

543 551

556 560 566 575

593.

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8 13

26 34

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68 449 AA A CONTENTS

MAY The Renal Pathology of Toxemia of Pregnancy

ALBERT ALTCHEK, NILE L. ALBRIGHT, and SHELDON C. SOMMERS Enzymes of Glycogen Metabolism in the Squamous Epithelium of the Cervix:

A histochemical study ROBERT FIENBERG and RICHARD B. COHEN Unusual Tumors of the Female Urethra JAY Y. GILLENWATER and H. M. BURROS Glomerular Filtration Rate in Normal Pregnancy and Early Postpartum Period

M. N. EL-MAHALLAWI, D. SEIF EL-DIN, M. MAHRAN, M. S. SABOUR, and H. E. FADEL Fertility Inhibition by an Injectable Progestogen Acting for 3 Months: A clinical

survey of 130 fertile women treated with m@rethisterone enanthate

JUAN ZANARTU and CARLOS NAVARRO Conception Control by a Single Monthly Injection

ARTURO ESQUIVEL and LEONARD E. LAUFE Norgestrel, A Low Dose, Oral Progestogen for Fertility Control: Supplementary report

MAXWELL ROLAND, MAX FRIEDMAN, and RALPH J. HESSEKIEL Advanced Intraligamentary Pregnancy: Report of a case with survey to date

HARRY K. ZIEL, FREDERICK S. MIYAZAKI, T. HART BAKER, and JERALD D. WHITE Primary Pelvic Peritoneal Pregnancy

EDUARD C. FRIEDRICH, JR. and CHARLES A. RANKIN, JR.

Granulosa-Theca Cell Tumors: A clinical review of 102 patients

ALLEN J. DINNERSTEIN and JAMES A. O'LEARY Hyperemesis Gravidarum: I. Evidence of hepatic dysfunction

REUBEN H. ADAMS, JUDY GORDON, and BURTON COMBES Hyperemesis Gravidarum: II. Alterations in sulfobromophthalein sodium-removal

mechanisms from blood BURTON COMBES, REUBEN H. ADAMS, JUDY GORDON, VICTOR TRAMMELL, and HISAO SHIBATA Cesarean Section for Fetal Distress IAN G. L. VAN PRAAGH and HAROLD M. M. TOVELL Transplacental Inoculation of Fatal Herpes Simplex in the Newborn: Report of 2 cases

RAYMOND A. GAGNON Recurrent Benign Intracranial Hypertension (Pseudotumor Cerebri) During Pregnancy

MARTA ELIAN, N. BEN-TOVIM, M. BECHAR, and B. BORNSTEIN Sarcoma Botryoides of the Cervix: Treated by vaginal hysterectomy and subtotal

vaginectomy H. OLIVER WILLIAMSON and FORDE A. MC IVER

Benign Masses of Bartholin’s Gland: Solid ademonas, ademonas with cyst, and Bartholin’s gland with varices and thrombosis or cavernous hemangioma

J. H. SMITH FOUSHEE, WILLIAM J, REEVES, and JAMES A. MC COOL Endometrial Carcinoma in Young Women: A clinical profile EDWIN P. PETERSON Aspiration Biopsy of Bone: Use in the management of metastatic gynecologic malignancy

ALFRED S. LLORENS and RUTH M. GRAHAM Perinatal Mortality and Amnionitis in a General Hospital Population

DANNY M. CLARK and GAIL V. ANDERSON Monilial Chorionitis Associated with an Intrauterine Contraceptive Device

ABRAHAM I. SCHWEID and G. BRUCE HOPKINS Arteriovenous Fistula Following Pelvic Operations

GEORGE W. MORLEY and S. MARTIN LINDENAUER Localization of Fibrinolytic Activity in the Rat Oviduct

KONSTANTINOS TYMPANIDIS and TAGE ASTRUP Pessary Treatment of the Incompetent Cervical Os MEYER VITSKY Instrument & Method: High Puncture of the Fetal Membranes W. L. G. QUINLIVAN A Curved Modification of the lowa Trumpet LEE HUBERTY and F. J. HOFMEISTER

595 608 617

621

627 634 637

643 649 654 659

665 674 682 685 689

695 702 708 714 719 722 727 732 734 736

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CONTENTS

Views and Reviews: Radical Vulvectomy for Carcinoma of the Vulva

THOMAS E. HOUSE and LAWRENCE L. HESTER, JP..

Letter Book Reviews

JUNE

Time Necessary for Conversion of Normal to Dysplastic Cervical Epithelium

CLIFFORD H. FOX Shallow Conization of the Cervix

WILLIAM E, CRISP, HARRY SHALAUTA, and WARREN A. BENNETT Comparative Ultrastructure of the Mammalian Amnion !

RALPH M. WYNN end GARY L. FRENCH Tuberculous Meningitis in Pregnant and Puerperal Women

IVAN A. D’CRUZ and ARVIND C. DANDEKAR Coexisting Brenner Tumor and Struma Ovari: (Mature Gonadoblastoma) :

Report of a case HARVEY Z. KLEIN, SHERMAN H. STRAUSS, and ALLEN M. UNGER Primary Cesarean Section in the Grand Multipara SIDNEY A, JONES and ERNEST W. LOWE Effects of Pregnancy on the Diameter of the Uterine Arteries in the Rabbit:

Pelvic arteriography J. C. SMITH, W. A. W. WALTERS, and JOAN E. SPONG Peritoneal Respuiise to Polyethylene Foreign Bodies

ROBERT ECHENBERG and WILLIAM J. LEDGER Arteriovenous Fistulas of the Female Pelvis: A diagnostic problem

DAVID G. DECKER, CHARLES R. FISH, and JOHN L. JUERGENS Suture of the Uterine Rupture OSCAR AGUERO and SAUL KIZER Normal Pregnancy in a Patient with Multiple Myeloma

FRED ROSNER, BERNADETTE C. SOONG, MENDEL KRIM, and SHERWOOD P. MILLER Three New Synthetic Progestins in the Treatment of Endometriosis

IONE A. KOURIDES and ROBERT W. KISTNER Amniocentesis of the Sensitized Rh-Negative Patient: A combined study in 2

community hospitals

JOSEPH J. PRICE, GERALD D. GUNSTER, and SAMUEL J. BRACKEN, JR.

Antepartum Hemorrhage: Analysis of 304 patients in a private institution

JAMES A. MC CULLOUGH, CREIGHTON L. EDWARDS, and WILLIAM P. DEVEREUX Antimicrobial Properties of the Endometrium

P. J. KOZINN, W. POMERANCE, L. CAROLINE, A. OKAS, and C, TASCHDJIAN Death from Septicemia Following Insertion of an Intrauterine Device:

Report of a case WILLIAM J. LEDGER and FRANK J. SCHRADER Angular Pregnancy: Report of a case THOMAS W. MC ELIN and ROBERT LA PATA Instrument & Method: Auto-Suture in Abdominal Hysterectomy ERIC KAHN Editorial: Arterial Physiology of the Human Female Pelvis R. CLAY BURCHELL After Office Hours: Whither IUD? The Present and Future of Intrauterine

Contraceptives CHARLES H. BIRNBERG and MICHAEL S, BURNHILL After Office Hours: A Modest Proposal for Preventing Choriocarcinoma

Among Innocent Mothers WILLIAM B. OBER

Letters Book Reviews Indexes

Authors

Subjects and Titles

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