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Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients

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Academic year: 2020

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Figure

Figure 1: PTEN and PIK3CA protein and mutation view. Results from whole exome sequencing of ten cases with complex atypical hyperplasia (CAH): PTEN (A) and PIK3CA (B) were significantly mutated indicated by protein view in the diagram
Figure 2: PI3K mRNA signature score and Stathmin protein expression. The PI3K mRNA signature score defined by Gustafson et al
Figure 3: Immunohistochemical staining of PTEN associates with mRNA and protein RPPA-expression
Figure 4: mRNA expression levels of STMN1 and KRAS in relation to body mass index in CAH patients

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