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Impact of Early Antiretroviral Therapy on Detection of Cell Associated HIV 1 Nucleic Acid in Blood by the Roche Cobas TaqMan Test

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Figure

FIG 1 Linearity of cell-associated HIV (CAH) on dilutions of 8E5 cells. Washed 8E5 cultured cellsycontaining a single copy of integrated HIV genome per cell were spiked into whole blood at 25, 50,100, 200, 500, and 1,000 cells/ml blood
FIG 3 Detection of HIV-1 nucleic acid in frozen whole blood (FWB) and cell pellet samples of ART-treatedlogHIV-1-infected individuals (chronic infection) with no detectable plasma HIV-1 RNA by the RocheAmplicor HIV-1 DNA PCR test, v1.5 (left), and the Roch
TABLE 1 Sensitivity, specificity, and positive and negative predictive values of modified CAP/CTM assay
FIG 6 Time course of decay of cell-associated HIV (CAH) nucleic acid after initiation of ART treatment during acute HIV-1 infection
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