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Establishment and antitumor effects of dasatinib and PKI-587 in BD-138T, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant EGFR amplification and PTEN deletion

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Academic year: 2020

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Figure

Figure 1: Case presentation of patient 138T with muscle-invasive bladder cancer and validation of patient-derived tumor tissue
Figure 2: Identification of gene alterations in 138T muscle-invasive bladder cancer. (A) Comparative genomic hybridization array analysis of the tumor from patient 138T, indicating the mutual EGFR amplification and PTEN deletion
Figure 3: Establishment and validation of patient-derived cells (PDCs) from 138T muscle-invasive bladder cancer (MIBC)
Table 1: In-vitro sensitivity of 138T PDC cell to a panel of targeted therapeutic agentsa
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