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dSet1 Is the Main H3K4 Di- and Tri-Methyltransferase Throughout Drosophila Development

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Figure

Figure 1 Therow gel lanes) lethal 5 locus encodes the Drosophila ortholog of the Set1 H3K4 methylase (dSet1)
Table 1 RNAi knockdown of Drosophila COMPASS members results in lethality
Figure 2 dSet1 mutations result in dra-matic losses of di- and trimethylatedH3K4 at multiple developmental timepoints
Figure 5 dSet1 physically interacts with theGST-Wds, or GST-Ash2 immobilized on glutathione sepharose beads(to remove nonspeci Drosophila COMPASS mem-bers Wds and Ash2
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