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<p>Caplacizumab as an emerging treatment option for acquired thrombotic thrombocytopenic purpura</p>

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Figure 1 The mechanism of action of caplacizumab.Notes: (A) The pathogenesis of aTTP; the presence of anti-ADAMTS13 autoantibodies inhibits the proteolytic cleavage of ultra-large vwF multimers by ADAMTS13, which results in the aggregation of platelets thr
Table 1 The efficacy and safety data of both Phase II TITAN and Phase III HERCULES trials

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