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Impact of pyrrolidine-bispyrrole DNA minor groove binding agents and chirality on global proteomic profile in Escherichia Coli

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Academic year: 2020

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Figure

Figure 1 Chemical structures of distamycin A, PySSPy, PyRSPy and 3A. (A) Distamycin A
Figure 2 E. coli DH5α growth after treatment with PySSPy,PyRSPy and 3A. E. coli DH5α in LB broth were treated with 0(square), or 300 μM PySSPy (triangle), PyRSPy (circle), and 3A(diamond) at 37°C for 15 hours
Figure 4 The expression of the proteins identified insolubilization and protein separation using an immobilized pH gradient gel strip (pH 4-7) and 12% SDS-PAGE gel
Table 1 Identification of differentially expressed proteins of E coli DH5α treated with PySSPy, PyRSPy and 3A

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