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Design, synthesis and in vitro antitumor activity of novel phthalazin 1,4 dione/chalcone hybrids and phthalazin 1,4 dione/pyrazoline hybrids

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Academic year: 2020

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Figure

Table I In vitro cytotoxic activities of the newly synthesized compounds against HCT-116 and MCF-7 cell lines
Table II Fit values of the investigated compounds 4a-h, 5a-c and 6b-d to the hypothetical model
Fig. 6: Docked poses of Compound 6b in VEGFR-2 binding site generated by MOE docking. Simplified 2D ligand interaction of 6b

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