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Age dependent hepatic lymphoid organization directs successful immunity to hepatitis B

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Figure

Figure 1HBV-specific immune responses that direct viral clearance are first detected in the liver
Figure 2Adult mice show increased macrophage-associated lymphocyte organization, parenchymal lymphocyte clustering and IgGand young (bottom) HBVEnvtion, (clusters per frame (≥2 cells within 15 tissue 8 days after adoptive transfer of adult WT splenocytes
Figure 3Macrophage depletion leads to an immune response that correlates with chronic HBV and impaired hepatic lymphocyte organization
Figure 4Age-dependent hepatic CXCL13 expression is by macrophages and is susceptible to clodronate liposome treatment
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