Antibodies for Breast Cancer Research
Antibodies: detection, imaging, diagnostic, etc . Increase Your Efficiency and Value with Consistent Performance
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Creative Biolabs offers high quality ready-to-use catalogue antibodies, as well as flexible and
comprehensive customized services for the antibody production to facilitate the basic discovery of breast cancer. Empowered by extensive experience and senior teams, we are committed to offering cutting- edge antibodies with superior performance for a wide range of applications to best maximize the success of your projects at the forefront of technological innovation.
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Antibodies for
Breast Cancer Research
Breast Cancer
Breast cancer is the principle cause of cancer-related mortality among women worldwide. It's highly heterogeneous and can be classified into 3 types - TNBC, HER2+ and Luminal (non-HER2+).
• ESR1
• HER2/ERBB2
• Ki67
• Progesteron receptor (PGR)
Key markers
A Quick Glance at Key Targets in Breast Cancer
Kind reminder: If you are interested in any other targets, please visit our website or contact us.
Key signaling factors
Types, frequency and associated mutant genes
• TBL1XR1
• p16Ink4A /CDKN2A
• MYB
• FOXA1
• GATA3
• CBFB
• RUNX1
• NCOR1
TNBC Triple-negative breast cancers are ER-PR-HER2- and show significant but not complete overlap with the basal-like subtype of breast cancer (which is defined by differentiation state and gene expression profile).
HER2+breast cancers have luminal features and are characterized by ERBB2 gene amplification and overexpression, leading to a dependency on HER2 signaling.
Luminal (non-HER2+)
tumors are typically estrogen receptor positive, displaying high ERα levels.
These tumors are dependent on estrogen for growth and, therefore, respond to endocrine therapy.
TNBC 10%
HER2+
20% Luminal, non-HER2+
70%
• ERK2/MAPK1
• MAP2K4
• JNK/MAPK8
• STMN2
• PIK3R1
• PIK3R3
• Cyclin D1/CCND1
• Cyclin D3/CCND3
• CDK4
• PRB1/2
• NCOA3
• MYC
• AKT2
• PTEN
• MDM2
• p53
• TBX3
• GSK3B
• SRC
• RAS
• BRAF
• MEK1
• MEK2
• ERK1/MAPK3
• TP53
• PIK3CA
• GATA3
• MAP3K1
• MLL3
• CDH1
Commonly mutated targets
• USH2A
• PTEN
• RUNX1
• NCOR1
• RB1
• TBX3
• FOXA1
• CDKN1B
• PIK3R1
• CTCF
• NF1
• SF3B1
• AKT1
• CBFB
Antibodies for
Breast Cancer Research
Antibodies for commonly mutated targets
Targets Clone Applications Species reactivity Cat.No.
TP53
1285C WB, IHC, IF, P, FC Human, Mouse CBMAB-1838CQ
CBWJW-083 WB, P, PE Human, Mouse, Rat CBMAB-T0002-WJ
1F7 IP, M, WB Human CBMAB-0266-LY
PIK3CA
CBYC-P379 WB, IP, IC, IF Human CBMAB-P1796-YC
H.843.0 P, IP, WB Cattle, Human,Mouse, Rat CBMAB-P1797-YC
4F3 WB, E, F, IC, IF Human CBMAB-P1795-YC
GATA3
1A12-1D9 IC, IF, P, IP, WB Human, Mouse, Rat CBMAB-G2217-LY
7B5 E, IH, P, WB Human CBMAB-G2223-LY
CBLG1-676 IC/IF, P, IP, WB Human CBMAB-G2244-LY
MAP3K1
CBFYM-0114 F, IF, P, WB Human CBMAB-M0132-FY
9D8 WB Human CBMAB-1022-YC
3A10 E, F, IC, IF, WB Human, Mouse CBMAB-1021-YC
MLL3 CBFYM-1193 WB, E Human CBMAB-M1350-FY
1686CT202.60.69 WB Human CBMAB-K1430-LY
CDH1 CBYY-C0043 IS, WB, IF, IH, IP Human, Dog, Mouse, Rat CBMAB-C0119-YY
3G44 F, IF, IH, IP, WB Human, Mouse CBMAB-C6150-LY
3G42 E, F, IF, IH, IP, WB Human CBMAB-C6148-LY
USH2A CBXU-038 WB Human CBMAB-U0154-CQ
PTEN
10BA33 IF, WB Human CBMAB-1516CQ
D4.3 WB, IP Human, Mouse, Rat, Hamster,
Monkey, Dog, Chicken CBMAB-P3310-YC
1B8 E, F, IC, IF, WB Human, Mouse CBMAB-P3306-YC
RUNX1 CBYC-A1038 F Human, Monkey CBMAB-A4717-YC
15B E, IC, P, WB Human CBMAB-A4712-YC
RXDMC F Human, Mouse CBMAB-R3861-CN
NCOR1 7A7A9 E, IH, P, WB Human CBMAB-N1470-WJ
CBWJN-0129 E, IH, WB Human CBMAB-N1469-WJ
9BA9 E, WB Human CBMAB-1448CQ
RB1
Rb1 (1F8) IH, IF Human CBMAB-C1002-CQ
CBXC-2448 WB, P, C Human, Mouse CBMAB-C0046-CQ
CBXC-2426 WB, IF Human, Mouse, Rat, Dog,
Primate, Rabbit CBMAB-C0034-CQ
TBX3 CBYJT-2161 WB, IP, IF, E Human,Rat, Mouse CBMAB-T1266-YJ
CBYJT-2160 WB, IP, F Human,Rat, Mouse CBMAB-T1265-YJ
CBYJT-2158 WB, E, P, F, IC, IF Human CBMAB-T1263-YJ
PIK3R1
U5 C, IP, WB Cattle, Human,Mouse, Non-
Human primate, Rat CBMAB-P1817-YC
2E7 E, M Human CBMAB-0832-CN
8C11 E, WB, P, IF, IC, F Human, Mouse CBMAB-P1814-YC
CTCF 2B12E2 E, WB, IF Human, Mouse CBMAB-C4674-LY
1D11 E, WB Human, Monkey CBMAB-C3807-LY
CBXC-1870 WB, IH, P Human CBMAB-C5096-CQ
NF1
2D1 E, WB Human CBMAB-N2125-W
A-12 WB, IP, IF, P, E mouse, rat, Human CBMAB-N2129-WJ
CBWJN-0652 WB, E, IP, P Human, Mouse, Rat, Guinea
Porcine CBMAB-N0290-WJ
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Antibodies for
Breast Cancer Research
To be continued.
Popular antibodies for key markers
Creative Biolabs' antibodies help meet your breast cancer research needs and budget requirements, increasing efficiency and offering the best value for a wide range of applications and specific assays.
ESR1
Targets Clone Applications Species reactivity Cat.No.
SF3B1
CBXS-5436 WB Human, Mouse, Rat, Monkey,
Hamster, Cattle CBMAB-S2647-CQ
CBXS-2265 WB, IP, IF, E Mouse, Rat, Human CBMAB-S5027-CQ
CBXS-1300 WB, P, IF Human CBMAB-S4159-CQ
AKT1
4E10 WB, IH, IF, F Human,Dog, Rat, Monkey, Mouse CBMAB-A2050-YC
4C3 E, IP, PLA, RNAi Human CBMAB-A2048-YC
5C10 E, WB Human,Mouse, Rat, Dog CBMAB-A2053-YC
CBFB
A-4 WB, IP, IF, E Human CBMAB-P0143-YC
8C84 DB, C, WB Human CBMAB-C9108-LY
1E6 IP, WB, M Human CBMAB-0194-YC
FOXA1
3C1 WB, E, P, IF Human CBMAB-F0941-CQ
2D7 E, WB, IH Human CBMAB-F2967-CQ
CBXF-3132 IC, IH, WB Human, Mouse CBMAB-F3828-CQ
CDKN1B
SX53G8 P Human,Mouse, Rat, Primate CBMAB-P0194-YC
0.N.491 F, IF, IH, IP, WB Dog, Human,Mouse, Rat CBMAB-P0188-YC
CBLC-LY-008 F, IF, C, P, IP, WB Mouse CBMAB-C9407-LY
Targets Clone Applications Species reactivity Cat.No.
ESR1 ESR1/420 WB, F, IF Human CBMAB-E0318-FY
2G112B3 E, WB Human CBMAB-1204-YC
CBFYE-1267 IC, IH, IP, WB Hamster, Human, Mouse, Rat CBMAB-E1850-FY
Antibodies for commonly mutated targets
HER2/ERBB2
Targets Clone Applications Species reactivity Cat.No.
HER2/
ERBB2
4D5-8
(TrasTuzumab) F, E, IH, MC Human CBMAB-E1659-FY
SPM495 P, WB Human, Mouse, Rat, Monkey CBMAB-E1645-FY
9G6 F, IF, C, P, IP, WB Human CBMAB-E1648-FY
The anti-HER2 antibody shows distinct
membranous positivity in HER2-negative and positive ductal carcinoma.
The anti-ESR1 antibody shows obvious nuclear positivity in human breast tissue using IHC.
By western blot analysis, ESR1 is clearly detected around 68KDa.
Antibodies for
Breast Cancer Research
Targets Clone Applications Species reactivity Cat.No.
SRC CBXS-3318 F, IC, IH, IP, WB Cattle, Hamster, Human, Monkey,
Mouse, Rat CBMAB-S6057-CQ
CBXS-2306 IC, IP, WB Chicken CBMAB-S5068-CQ
CBXS-1773 IH Human CBMAB-S4590-CQ
RAS Y13-259 WB Mouse, Rat, Human CBMAB-G6077-LY
1C8 WB Human, Monkey CBMAB-G6073-LY
CBFYH-1953 WB, IH, IF Human, Dog, Rat, Monkey, Mouse CBMAB-H2964-FY BRAF
15B239 WB Human, Mouse CBMAB-R0430-CN
CBYY-2086 IH, P, WB Human, Dog CBMAB-2435-YY
CBYY-1674 F, IC, IH, P, WB Human CBMAB-2023-YY
MEK1
25/MEK1 F Human, Chicken, Dog, Mouse, Rat CBMAB-M0108-FY CBFYM-1441 WB, P, IF, IP Human, Mouse, Rat, Zebrafish CBMAB-M1601-FY CBFYM-1438 WB Dog, Human, Mouse, Non-human
primate, Rat CBMAB-M1598-FY
Ki67
Targets Clone Applications Species reactivity Cat.No.
Ki67
3D11 IH, P, WB Human CBMAB-K2136-LY
4A1 IA, IH Human CBMAB-K2137-LY
SP6 IH, IC/IF, P, C Human, Mouse, Rat, Dog CBMAB-K2173-LY
The anti-Ki67 antibody shows obvious nuclear positivity in human lymph node via IHC. By ICC- IF, Ki67 is detected in nucleoli of human cell line U-2OS.
Progesteron receptor (PGR)
Targets Clone Applications Species reactivity Cat.No.
PGR
4E9 E, IF, P, WB Human CBMAB-P1613-YC
0.N.529 IF, IH, IP, WB Equine, Human,Pig, Sheep CBMAB-P1605-YC
8A11H1 WB Human CBMAB-P1614-YC
By immunofluorescence and immunohistochemistry, PGR is detected in MCF-7 cell and formalin-fixed paraffin-embedded human breast cancer tissue.
Popular antibodies for key signaling factors
Key signaling pathways involved in breast cancer include RAS/RAF, RAS/MAPK, PI3K/AKT etc.
Creative Biolabs provides a wide range of antibodies for involved signaling factors, but not limited to these. Please contact us for more products information.
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Antibodies for
Breast Cancer Research
Targets Clone Applications Species reactivity Cat.No.
MEK2
CBFYM-1465 WB, E, F, IF Mouse, Rat, Human CBMAB-M1625-FY
CBFYM-1456 F Human, Chicken, Dog, Frog,
Mouse, Rat CBMAB-M1616-FY
CBFYM-1455 F, IC, IF, WB Human CBMAB-M1615-FY
ERK1/MAP K3
3C9 E, IC, IF, P, IP, WB Human CBMAB-1195-YC
1E5 E, P, F, IC, IF, WB Human, Mouse, Rat, Monkey CBMAB-1192-YC 12D11 WB, CI, IH, IF, P Human, Mouse, Primate CBMAB-E2167-FY ERK2/MAP
K1
4F3-A10-E7 WB Human,Mouse, Rat CBMAB-P0477-YC
CBFYM-1574 E, WB, IH, IC Human, Mouse, Rat, Sheep CBMAB-M1740-FY 4C11 E, IC, IF, IH, C, P, WB Human, Mouse, Monkey CBMAB-1201-YC MAP2K4
CBXS-4988 F, IF, IH, P, IP, WB Human CBMAB-S2210-CQ
CBXS-5919 F, IF, IH, P, WB Human, Dog CBMAB-S0768-CQ
CBFYM-1486 WB, IP Human, Mouse, Rat, Monkey,
Dog CBMAB-M1646-FY
JNK/MAPK 8
41/JNK/SAPK
(pT183/pY185) WB Human, Mouse, Rat CBMAB-0199-WJ
H.715.7 IP, WB Hamster, Human, Mink, Mouse,
Primate, Rat CBMAB-0363-WJ
2F3 WB, IP, E, P Human CBMAB-0148-WJ
STMN2 CBXS-3507 E, WB Human CBMAB-S6236-CQ
CBXS-1399 WB, IP Mouse, Rat, Human CBMAB-S4257-CQ
CBXS-0804 SE, E, WB Human CBMAB-S3731-CQ
PIK3R1
8C11 E, WB, P, IF, IC, F Human, Mouse CBMAB-P1814-YC
2E7 E, M Human CBMAB-0832-CN
U13 WB, IP Mouse, Rat, Cattle, Human,
Monkey CBMAB-P1816-YC
PIK3R3 2F8 E, PLA, WB Human CBMAB-P1824-YC
CBYC-P386 WB, P, IC, IF Mouse, Rat, Human CBMAB-P1825-YC AKT2
5B5 WB, IP Human,Mouse, Rat, Monkey CBMAB-A2093-YC
AW114 WB, IP Human, Rat CBMAB-A2101-YC
D16-H E, WB, IF, IC, IP Human,Mouse, Rat CBMAB-A2102-YC
PTEN
10BA33 IF, WB Human CBMAB-1516CQ
D4.3 WB, IP Human, Mouse, Rat, Hamster,
Monkey, Dog, Chicken CBMAB-P3310-YC
1B8 E, F, IC, IF, WB Human, Mouse CBMAB-P3306-YC
MDM2 CBFYM-1965 E, F, IC, IF, WB Mouse CBMAB-M2140-FY
CBFYM-1964 E, WB, IH Human, Mouse, Rat CBMAB-M2139-FY
CBFYM-1961 IC, IF, IH, IP, WB Human CBMAB-M2136-FY
p53
7A4 IF, IH, IP, WB Common fruit fly CBMAB-0433-LY
CBWJW-083 WB, P, PE Human, Mouse, Rat CBMAB-T0002-WJ
CBLG1-2390 IF, SE, E, WB Human CBMAB-G6398-LY
TBX3 CBYJT-2161 WB, IP, IF, E Human,Rat, Mouse CBMAB-T1266-YJ
CBYJT-2159 E, IC, WB Human CBMAB-T1264-YJ
CBYJT-2160 WB, IP, F Human,Rat, Mouse CBMAB-T1265-YJ
GSK3B E.948.2 P, IP, WB Human, Mouse, Primate, Rat CBMAB-G5224-LY
3A11 E, WB Human, Mouse, Rat CBMAB-G0845-LY
3D6B4 WB, F, E, IH, MC Human, Mouse CBMAB-H1379-FY
Antibodies for key signaling factors in breast cancer
Antibodies for
Breast Cancer Research
To be continued.
Targets Clone Applications Species reactivity Cat.No.
Cyclin D1/CCND 1
CD1.1 WB, F, E, IH, IP, P, C Human, Rat CBMAB-C4698-CQ
SP4 WB, IH, IF, P Human, Mouse, Rat, Baboon CBMAB-C4697-CQ
CBXC-1590 E, F, IH, IP, WB Human, Rat CBMAB-C4700-CQ
Cyclin D3/CCND 3
CBYY-C0337 WB, IH Human CBMAB-C1127-YY
CBFYC-1042 F, IF, IH, IP, N, WB Human, Mouse, Rat CBMAB-C1099-FY CBFYC-1040 WB, IF, IH, IP Mouse, Dog, Human, Rat CBMAB-C1097-FY CDK4
5J210 IF, IH, IP, WB Human, Mouse, Rat CBMAB-C7749-LY
3F9-B12-C8 WB, E Mouse, Rat, Dog, Human, Pig CBMAB-C6085-LY 0.N.199 IF, IP, WB Human, Mouse, Pig, Rat CBMAB-C1404-LY
PRB1/2 BA0343 WB, P Human CBMAB-0690CQ
NCOA3
AX15.3 E, IH, P, IP, WB, CI Human CBMAB-S2958-CQ
AC3 WB, IH, IF, P Human CBMAB-N0184-WJ
F-2 WB, IP, IF, E mouse, rat, Human CBMAB-N1451-WJ
MYC
9E11 WB, CI, F, E, IH, IP,
P, C, MC Human, Mouse, Chicken, Yeast CBMAB-C9324-LY
3G32 E, IF, IH, IP, WB Human, Mouse CBMAB-C6137-LY
CT14.G4 F, IF Human, Primate CBMAB-C0609-CQ
MYB
10A3 IP, WB Human, Mouse, Zebrafish CBMAB-V0114-LY
D-12 WB, IP, IF, E Mouse, Rat, Human CBMAB-A4588-YC
4-E3 WB, IP Human, Mouse, Xenopus CBMAB-A4587-YC
FOXA1
4F6 E, IF, P, WB Human CBMAB-F2445-CQ
CBFYH-0203 WB, IP, IF, P, E Mouse, Rat, Human CBMAB-H1077-FY
SP88 F, P Human CBMAB-F0220-CQ
GATA3
1A12-1D9 IC, IF, P, IP, WB Human, Mouse, Rat CBMAB-G2217-LY
7B5 E, IH, P, WB Human CBMAB-G2223-LY
CBLG1-676 IC/IF, P, IP, WB Human CBMAB-G2244-LY
CBFB
A-4 WB, IP, IF, E Human CBMAB-P0143-YC
4D9 IP, WB, M Human CBMAB-0199-YC
CBYY-C1023 DB, IC, WB Human CBMAB-C2460-YY
RUNX1
CBYC-A1038 F Human, Monkey CBMAB-A4717-YC
15B E, IC, P, WB Human CBMAB-A4712-YC
RXDMC F Human, Mouse CBMAB-R3861-CN
NCOR1
7A7A9 E, IH, P, WB Human CBMAB-N1470-WJ
CBWJN-0129 E, IH, WB Human CBMAB-N1469-WJ
9BA9 E, WB Human CBMAB-1448CQ
TBL1XR1
CBYJT-2103 E, WB, IH, IC Human,Mouse, Rat, Cattle, Pig,
Dog, Zebrafish CBMAB-T1202-YJ
CBYJT-2102 WB, E, P, IC Human,Mouse CBMAB-T1201-YJ
CBYJT-2105 WB, IP, CI Human, Monkey CBMAB-T1204-YJ
p16Ink4A /CDKN2A
5-C3-1 IF, IH, IP, WB Mouse CBMAB-C7387-LY
2D9A12 WB, P Human CBMAB-C4943-LY
1E12E10 WB, P Human, Mouse, Rat CBMAB-C3919-LY
Antibodies for key signaling factors in breast cancer
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Antibodies for
Breast Cancer Research
Antibody Services Guidance
Specific
Yes
What's my target?
Popular
Catalogue Ab Custom Ab
No
Suit my project
Available or not in Creative Biolabs?
Order the Catalogue Ab Online
Test the Ab
Mouse or rabbit?
Specific epitope
Batch to batch reproducibility Monoclonal Ab Polyclonal Ab
Epitope synthesises or not?
Creative Biolabs offers comprehensive antibody products and related services. Please contact us for more detailed information and our team will get back to you as soon as possible. We are always here to serve you to help promote your projects. The list above only exhibits a small part of our products. Please visit our website for more information. https://www.antibody-creativebiolabs.com
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Antibodies for
Breast Cancer Research
Custom Antibody Service Process
Innovative technologies and ideas Numerous worldwide customers
High-level Ph.D. scientists and experienced technicians High efficiency and short turnaround time
Close collaboration
Extensive forefront knowledge sharing Advanced and one-stop platforms
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With extensive experience and over a decade superior antibody services for numerous worldwide customers, Creative Biolabs has blossomed into a service leader in the field of antibody products and services. We offer a comprehensive set of package services and also individual modules, and aim to maximize the success of your breast cancer research discovery and development.
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Delivery Submit protein
sequence Antigen design Antigen synthesis Antibody production
and purification Quality control
WB IHC ELISA IP/ChIP IF/FC Functional
A wide range of applications
assay
Antibodies for
Breast Cancer Research
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custom service & solution provider.
Leverage the expertise of our senior scientists to obtain a wide array of antibodies or custom products to fit your project.
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