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Evaluation of off target and on target scoring algorithms and integration into the guide RNA selection tool CRISPOR

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Figure

Figure S2). A relationship between GC content and spe-
Figure S3). Therefore, CRISPOR does not allow indels,
Fig. 3 Cross-study analysis of MIT specificity scores as calculated by CRISPOR versus the number and strength of off-targets found.sequences, CRISPOR guide specificity scores are shown ( a For 31 guidex-axis), as well as the number of off-targets (y-axis)
Fig. 4 Heat map of Spearman rank correlation coefficients between efficiency scores and datasets
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