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Mutational signatures reveal the role of RAD52 in p53 independent p21 driven genomic instability

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Figure

Fig. 1 Reduction of single nucleotide substitution (SNS) and malfunction of the translesion DNA synthesis and repair (TLS) process upon protractedand filtering were performed with the use of Samtools and VCFtools in non-induced and escaped (Saos2- and Li-F
Fig. 2 Decreased activity of the base excision repair (BER) pathway in cells with sustained p21WAF1/Cip1 expression
Fig. 3 Decreased activity of the nucleotide excision repair (NER) pathway in cells with prolonged p21WAF1/Cip1 expression
Fig. 4 Extended p21WAF1/Cip1 over-expression shapes the mutational signature landscape
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