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Anti Proliferative and Apoptotic Activities of Müllerian Inhibiting Substance Combined with Calcitriol in Ovarian Cancer Cell Lines

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Fig. 1. Effects of MIS and calcitriol on the viability of ovarian cancer (OCa) cells. (A) Cells were treated with a range of MIS (35.5–284 nM) to determine the IC50 for each cell line
Fig. 2. Viability and proliferation assays conducted with ovarian cancer (OCa) cell lines treated with MIS and calcitriol (relative cell growth as a function of time)
Fig. 3. Calcitriol enhances MIS-induced apoptosis in OCa cell lines. Cells (1×105/well) were pretreated with or without calcitriol (50 μM) for 4 h prior to the addition of MIS (71 nM)
Fig. 5. Calcitriol increases MIS-induced ERK phosphorylation in SKOV3 cells. (A) Western blot analysis of ERK and phosphorylated ERK levels in SKOV3 cells treated with MIS

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