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Prediction of solubility of practically insoluble drugs in water/ethanol solvents using non empirical methods

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Figure

Table 1. Predicted solubilities of ibuprofen in water/ethanol mixed solvent using cosmo-rs and UNIFAC
Table 2. Predicted solubilities of diazepam in water/ethanol mixed solvent using COSMO-RS
Table 3.  The root mean square error (RMSE) and the average absolute error (AAE) of predicted logarithmic mole fraction solubility in water/ethanol mixtures
Table 4. Calculated polarizabilities of drug-like compounds  in water
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