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Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133 tumor initiating cells

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Figure

Figure S2A). To confirm if this increased gene expression
Figure 2: CD133+ cells have increased glycolytic activity. CD133+ cells had increased uptake of glucose (A) compared to CD133−cells
Figure 3: CD133+ cells have increased LDH expression and activity. LDH1 (A) and MCT4 (B) expression was increased in CD133+ cells
Figure 4: TCA cycle in CD133+ cells. CD133+ cells had increased TCA cycle intermediates like fumarate (A) and alpha ketoglutarate (B)
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