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Mucopolysaccharidosis type VI phenotypes-genotypes and antibody response to galsulfase

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Figure

Table 1 ARSB genotypes and phenotypes of 12 MPS VI patients
Figure 1 Transient expression of wildtype and mutant ARSBcDNA constructs. COS-7 cells were transfected with wildtype (wt)and mutant cDNA constructs
Figure 3 Antibody titer of patient 2 by immunoprecipitation.A fixed amount of galsulfase was incubated with seriallydiluted serum of patient 2
Figure 4 Antibody binding of galsulfase during infusion. Blood-plasma samples were collected from patient 2 and patient 6 just before startof galsulfase infusion (0 min) and at time points thereafter
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