Regulatory T cells: friend or foe in immunity to infection

To investigate whether the mCMV clearance in chronically FV-infected mice was negatively influenced by the fact that FV- expanded Tregs reduced mCMV-specific CD8 ⫹ T cell responses,

Thus, the increased expression of costimulatory molecules on FV-infected B cells (Fig. 1) was associated with significantly better in vitro APC activity compared to uninfected B

The increased regulatory dendritic cell DC T M immunoregulatory mechanisms mediated in part by release of IL-10 and TGF- Recently, Min and Rhee [70] have reviewed

Moreover, DAB 389 IL-2–mediated elimination of Tregs followed by vaccination with RNA-transfected DCs significantly improved the stimulation of tumor-specific T cell responses in

Myeloid‑ derived suppressor cells regulate immune response in patients with chronic hepatitis B virus infection through PD‑1‑induced IL‑10... Clinical significance and

The percentage of activated Helios + cells in the population of nTregs was higher in infected than in naïve mice (83 % to 69 % respectively) (Figure 1F, upper panel), whereas

In different settings, IL-17 has also been shown to promote the infiltration and develop of myeloid-derived suppressor cells (MDSC), which inhibit the activity of CTLs and thus

VacA- exposed dendritic cells produce IL-10 and induce the FOXP3 and contact-dependent differentiation of T-cells into CD4 þ CD25 þ FOXP3 þ regulatory T (Treg) cells