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Anaerobic radical enzymes for biotechnology

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Figure

Table 1. Key B12-dependant mutases and their reactions.
Figure 1. The Fe2S2 (butterfly-like structure, left) and Fe4S4 (cubane-like structure, right) iron sulfur clusters are important to many radical-based enzymatic reactions
Figure 2. (a) The organometallic coenzyme B12 features a corrin ring and an adenosyl moiety (R) bound to For Peer Reviewcobalt, poised to form (b) the reactive 5'-adenosyl radical (Ado•), which is an important radical catalyst generated in both B12-dependa
Figure 3. The structures of radical SAM enzymes show a distinctive TIM-For Peer Reviewbarrel architecture (a), with either a full-(β/α)8 barrel (left, biotin synthase, pdb ID 1R30, with second monomer of the dimer structure transparent) or, more commonly,
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