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The Voltage Sensor in Voltage-Dependent Ion Channels

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Figure

TABLE 1. Charge neutralization and total gating charge
TABLE 2. Results of accessibility studies of residues in the S4 segment of the Shaker K channel using cysteineand histidine scanning mutagenesis
FIG. 10. Schematic diagram showing the possi-ble outcomes of titration of histidine replacing acharge in the voltage sensor
FIG. 11. Relation between gating current (integral of gating current (M356C labeled with tetramethylrhodamine maleimide (TMRM) (A

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