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HLA typing from RNA-Seq sequence reads

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Figure

Figure 1 HLA sequence variability. (a) The helices encoded by exons 2 (a1- chain: orange) and 3 (a2-chain: red) of the HLA class I alleles bindpeptides (crystal structure 3OXR from PDB)
Figure 2 Workflow of seq2HLAgreatest number of reads is determined.repeated.. (a) RNA-Seq reads are mapped against the reference HLA sequences
Figure 3 Sensitivity versus specificity for different mapping and technical parameters applied to the 50 Montgomery test samples.
Table 1 HLA genotypes of Illumina Human Body Map individuals determined by seq2HLA .
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