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Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers

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Figure

Fig. 1 Microvesicle (MV) and exosome biogenesis in brain endothelial cells. Upon inflammatory stimuli, brain endothelial cells respond by releasing MVs (microvesicles) and exosomes into the bloodstream and/or in theory perivascularly
Table 1 Markers, means of preparation, source (circulation or tissue culture), and assay of brain barrier-derived EVs according to subtype (exosomes or microvesicles)
Table 1 (continued)
Fig. 2 Hypothetical schematic model of EV-cargo delivery to immune cells and EV-aided immune transendothelial migration
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