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Homoserine Toxicity in Saccharomyces cerevisiae and Candida albicans Homoserine Kinase (thr1Δ) Mutants

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Figure

FIG. 1. Threonine biosynthetic pathway.
TABLE 1. Phenotypes of threonine pathway mutants
TABLE 2. MIC80s of drugs that increase threonine pathway fluxa
FIG. 3. Increased flux through the threonine biosynthetic pathway is deleterious or lethal to thr1Strains included YJK1012 (PHOM3YJK1595 (combination with a(B)thr1� mutants
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