Infant Mortality in California
Michael Curtis, PhD
Jennifer Troyan, MPH
Nannie Song, MPH
Carrie Florez, MPH
Maternal, Child and Adolescent Health Division
Center for Family Health
Overview
• Data sources for infant mortality surveillance
• California infant mortality comparisons
• Selected key contributors to infant mortality:
– Preterm birth
– Safe sleep environments
Vital Statistics Datasets
•
The Birth Statistical Master Files contain data for all live births that
occurred in a calendar year
•
The Death Statistical Master Files contain data for all deaths that
occurred in a calendar year.
•
The Birth Cohort Files contain data for all live births that occurred
in a calendar year and death information for those infants who were
born in that year but subsequently died within 12 months of birth.
In 2012, California ranked 5
th
in state infant mortality rates.
9.0 8.8 8.7 8.2 7.6 7.6 7.5 7.5 7.4 7.3 7.3 7.1 7.0 7.0 6.9 6.9 6.7 6.7 6.6 6.5 6.5 6.4 6.4 6.3 6.3 6.2 6.1 6.0 5.9 5.8 5.8 5.8 5.4 5.3 5.3 5.2 5.2 5.2 5.2 5.1 5.0 5.0 4.9 4.8 4.7 4.6 4.5 4.4 4.3 4.2 4.2 0 2 4 6 8 10 12 Alabama Mississippi South Dakota Louisiana South Carolina Delaware Oklahoma Ohio North Carolina Tennessee West VirginiaKentucky Arkansas Pennsylvania Michigan New Mexico Maine Indiana Missouri Rhode Island Illinois MarylandVirginia Kansas Georgia North DakotaFlorida United StatesMontana ArizonaTexas WisconsinIdaho Oregon Iowa Washington Alaska Wyoming ConnecticutMinnesota New YorkHawaii Utah Nevada NebraskaColorado California New JerseyVermont Massachusetts New HampshireSource: Deaths: Final Data for 2012. National Vital Statistics Reports; vol 63 no 9. Hyattsville, MD: National Center for Health Statistics. Martin JA, Hamilton BE, Osterman MJ, et al. Births: Final data for
2012. National vital statistics reports; vol 62 no 9. Hyattsville, MD: National Center for Health Statistics. 2013.
If California was an independent nation, it would have
ranked 26
th
in infant mortality in the world
in 2011. (The US ranked 29
th
.)
13.6 7.7 6.1 4.9 4.9 4.8 4.7 4.3 4.3 3.8 3.8 3.6 3.6 3.6 3.6 3.5 3.5 3.5 3.4 3.3 3.2 3.1 3.0 2.9 2.7 2.5 2.4 2.4 2.3 2.1 0.9 0 2 4 6 8 10 12 14 16 Mexico Turkey United States Hungary Slovak Republic California Poland Luxembourg United Kingdom Australia Switzerland Austria Denmark Germany Netherlands France Ireland Israel Greece Belgium Spain Portugal Korea Slovenia Czech Republic Estonia Finland Norway Japan Sweden IcelandSources: OECD (2013), "Infant mortality", Health: Key Tables from OECD, No. 14, doi: 10.1787/inf-mort-table-2013-2-en http://www.oecd-ilibrary.org/social-issues-migration-health/infant-mortality_20758480-table9 Accessed 2/27/2014. Hoyert DL, Xu JQ. Deaths: Preliminary Data for 2011. National Vital Statistics Reports; vol 61 no 6. Hyattsville, MD: National Center for Health Statistics. 2012. Martin JA, Hamilton BE, Ventura SJ, et al. Births: Final data for 2011. National vital statistics reports; vol 62 no 1. Hyattsville, MD: National Center for Health Statistics. 2013.
California, 2011
Infant Mortality by Race/Ethnicity
10.5
3.8
10.7
4.6
3.9
9.7
0.0
2.0
4.0
6.0
8.0
10.0
12.0
In
fa
n
t
D
ea
th
s p
e
r
1
,00
0
L
iv
e B
ir
th
s
Number of Infant Deaths
Asian
Hispanic
White
B
lack
P
aci
fic I
sl
an
d
er
237
23
1,156
542
263
A
m
er
ican
Indi
a
n
19
California = 4.8
Note: Red line shows the 2011 California Infant Mortality Rate of 4.8 infant deaths per 1,000 live births. Width of bar shows percentage of population in each race/ethnicity group. Data Sources: California Birth Cohort File, 2011.
Infant Mortality among the Top 15 Counties with the
Largest Number of Infant Deaths, 2009-2011
County
2009-2011
Number of
Live Births
Number of
Infant Deaths
Infant Deaths per
1,000 Live Births
California
1,539,210
7,498
4.9
Los Angeles
403,343
1,969
4.9
San Bernardino
93,937
609
6.5
San Diego
133,462
586
4.4
Orange
116,786
469
4.0
Riverside
92,899
469
5.0
Fresno
48,714
339
7.0
Sacramento
60,493
329
5.4
Kern
43,537
268
6.2
Alameda
58,637
263
4.5
Santa Clara
72,795
242
3.3
San Joaquin
31,793
192
6.0
Contra Costa
37,095
185
5.0
Ventura
33,160
148
4.5
Stanislaus
23,486
125
5.3
Tulare
24,488
123
5.0
Note: Counties are sorted by descending order of infant death counts in combined years 2009-2011.
Blue highlight indicates the selected 9 counties with infant mortality rates greater than the CA state infant mortality rate of 4.9 infant deaths per 1,000 live births. Data Sources: California Birth Cohort File, 2009-2011.
Infant Mortality Rate and Number of Infant Deaths in
Counties with High Rates and Deaths, 2009-2011
5.3
5.0
5.0
5.0
7.0
6.5
6.2
6.0
5.4
0.0
2.0
4.0
6.0
8.0
In
fa
n
t
D
ea
th
s p
e
r
1
,00
0
L
iv
e B
ir
th
s
Number of Infant Deaths by County
Sa
n
J
oa
qui
n
609
Fresno
San Bernardino
Kern
Sacramento
Riverside
469
329
339
268
125
C
ont
ra
C
os
ta
S
tan
isl
au
s
Tul
a
re
Sa
n
J
oa
qi
n
123
185
192
Note: The 9 selected counties are sorted by descending order of infant mortality rates in combined years 2009-2011.
Red line indicates the 2009-2011 CA state infant mortality rate of 4.9 infant deaths per 1,000 live births. Width of bar shows number of infant deaths in each county. Data Sources: California Birth Cohort File, 2009-2011.
Prepared by the Epidemiology, Assessment and Program Development Branch, Maternal, Child and Adolescent Program, Center for Family Health
California, 2009-2011
Infant Mortality Rate by Race/Ethnicity
in Alameda and San Diego County
4.5
3.8
7.7
8.7
3.7
4.1
2.7
3.5
0.0
2.0
4.0
6.0
8.0
10.0
12.0
Alameda
San Diego
In
fa
n
t
D
ea
th
s p
e
r
1
,00
0
L
iv
e B
ir
th
s
Hispanic
Black
Asian
White
Note: 2009-2011nfant Mortality Rate is 4.5 infant deaths per 1,000 live births in Alameda and 4.4 per 1,000 live births in San Diego Source: California Department of Public Health, 2009-2011 Birth Cohort Files
Contributors to Infant Mortality: Selected Examples
• Preterm births
• Sudden Unexpected Infant Deaths
• Social Determinants of Health
The Contribution of Preterm Births
to Infant Mortality
Leading Causes of Infant Death:
National Center for Health Statistics (NCHS)
•
The NCHS List of 71 Rankable Causes of Infant Death is organized by
major ICD code groupings. However, this classification system does not
capture adequately the overall contribution of preterm birth to the infant
mortality rate.
•
Only deaths resulting from “disorder related to short gestation and low birth
weight not elsewhere classified” (ICD-10: P07.0-P07.3) seem to be explicitly
attributable to preterm birth. Therefore, many deaths involving preterm
births are classified elsewhere, in separate categories.
•
Example: Infant deaths attributable to respiratory distress syndrome, which
almost always results from incomplete lung maturation in preterm infants,
are counted in the category of respiratory distress of the newborn (ICD-10:
P22), instead of the category of disorders related to short gestation/low birth
Callaghan et al. Classification of Preterm-related Mortality
•
To more accurately reflect deaths attributable to prematurity, Callaghan et
al. used an alternative analytic approach to identify “preterm-related”
mortality.
•
First, the analysis was restricted to the 20 leading causes of death
•
For an underlying cause of death to be considered attributable to preterm
birth, ≥75% of infants whose deaths were attributed to that cause had been
born at <37 weeks of gestation.
•
Third, there must be a biomedical reason that the reported cause of death
was a direct consequence of preterm birth and one rarely seen at term or
that the cause of death resulted in preterm birth.
•
Lastly, the infant must be born preterm.
Leading Causes of Infant Death, California 2011
Short
gestation
and low
birth weight
16.1%
Congenital
anomalies
26.0%
6.1%
SIDS
6.4%
4.9%
All other
causes
40.5%
NCHS List of 71 Rankable
Causes of Infant Death
Maternal
complications of
pregnancy
Complications
of placenta,
cord and
membranes
Preterm-Related
Causes
35.6%
All
Other
Causes
64.4%
Callaghan et. al
Classification
Gestational age based on obstetric estimate with LMP replacement when OE missing. Valid gestational age range 17-47 weeks, excludes unknown gestational age Data Source: California Birth Cohort File, 2011.
Sudden Unexpected Infant Death
(SUID)
What is Sudden Unexpected Infant Death (SUID)*?
•
SUID is the sudden and unexpected death of an infant under one
year of age.
•
Most SUID deaths occur while an infant is sleeping; many are found
to have been in an unsafe sleep environment, which may or may not
have contributed to the infant’s death.
•
Most SUID are classified to a death diagnostic code of either:
– SIDS, R95
– Unknown/Undetermined, R99
Rate of Combined Causes of Infant Death (R95,W75,R99),
California, 2009-2013
49.4
53.3
51.6
51.4
54.4
0
10
20
30
40
50
60
70
2009
2010
2011
2012
2013
R
at
e
(p
e
r
10
0
,0
0
0
li
v
e
b
ir
th
s)
Sources: California Department of Public Health: Birth Statistical and Death Statistical Master File, years 2009-2013.
SIDS = ICD-10 Code R95 (Sudden Infant Death Syndrome); Accidental Suffocation = ICD-10 Code W75 (Accidental Suffocation and Strangulation in Bed); Undetermined = ICD-10 Code R99 (Other
Ill-Defined and Unspecified Causes of Mortality).
ICD-10 = International Classification of Diseases, 10th Revision
Prepared by: California Department of Public Health, Center for Family Health, Maternal, Child & Adolescent Health Division
269
Deaths
260
Deaths
272
Deaths
259
Deaths
259
Deaths
Rate of Combined Causes of Infant Death (R95,W75,R99)
by Non-Hispanic Black and White, 2009-2013
146.8
162.4
166.2
203.5
216.7
46.0
52.6
52.4
51.7
43.6
0
50
100
150
200
250
2009
2010
2011
2012
2013
R
at
e
(p
e
r
10
0
,0
0
0
li
v
e
b
ir
th
s)
Non-Hispanic Black
Non-Hispanic White
56
Deaths
42
Deaths
45
Deaths
45
Deaths
54
Deaths
65
Deaths
74
Deaths
73
Deaths
71
Deaths
60
Deaths
Sources: California Department of Public Health: Birth Statistical and Death Statistical Master File, years 2009-2013.
SIDS = ICD-10 Code R95 (Sudden Infant Death Syndrome); Accidental Suffocation = ICD-10 Code W75 (Accidental Suffocation and Strangulation in Bed); Undetermined = ICD-10 Code R99 (Other
Ill-Defined and Unspecified Causes of Mortality).
ICD-10 = International Classification of Diseases, 10th Revision
Individual and Neighborhood Income
• Individual income can impact health
• Individual income can also shape neighborhood
environments. Neighborhoods impact health:
– Availability of parks
– Community safety
– Access to healthy food
Measuring Health Status by the Concentration of
Poverty in a Neighborhood
•
Percent of the total population living below federal poverty level by
census tract. Data source is five year grouped data from the
American Community Survey (ACS)
•
Birth Cohort file geocoded and then merged with ACS census tract
level poverty rates.
•
Neighborhood level infant mortality rates based upon census tracts
categorized by the percent of the total population living below the
federal poverty level:
– 0 - 4.9%
– 5 - 9.9%
– 10 - 19.9%
California, 2013
Percent of Births by Neighborhood Poverty Concentration
11.0
20.9
31.6
36.5
0.0
5.0
10.0
15.0
20.0
25.0
30.0
35.0
40.0
0 - 4.9%
5 - 9.9%
10 - 19.9%
>= 20%
P
e
rc
e
nt
of
Li
v
e
Bi
rt
hs
Percent of Population below Poverty
Includes resident live births with a valid geocoded address
Data Sources: California Birth Statistical Master File, 2013; 2012 American Community Survey (ACS) 5-year file (2009-2013)
California, 2013
Percent of Births by Race/Ethnicity by Neighborhood
Poverty Concentration
4.8
5.2
18.7
18.3
13.2
12.4
31.0
30.0
30.5
28.9
32.7
33.3
51.4
53.5
17.6
18.4
0.0
10.0
20.0
30.0
40.0
50.0
60.0
Hispanic
Black
Asian
White
P
e
rc
e
nt
of
Li
v
e
Bi
rt
hs
0 - 4.9%
5 - 9.9%
10 - 19.9%
>= 20%
Includes resident live births with a valid geocoded address
Data Sources: California Birth Statistical Master File, 2013; 2012 American Community Survey (ACS) 5-year file (2009-2013)
California, 2008-2011
Infant Mortality Rate by Neighborhood Poverty Concentration
3.7
4.3
4.8
5.8
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
0 - 4.9%
5 - 9.9%
10 - 19.9%
>= 20%
In
fa
n
t
D
ea
th
s p
e
r
1
,00
0
L
iv
e B
ir
th
s
Percent of Population below Poverty
Includes resident live births with a valid geocoded address
Data Sources: California Birth Cohort Files, 2008-2011; 2012 American Community Survey (ACS) 5-year file (2008-2012)