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Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine specific antibodies

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Figure

Figure 1Antibody responses to 2009 seasonal TIV in young and elderly vaccinees. (IgA and IgG ELISA binding titer of PPAbs from individual vaccinees collected 1 week after vaccination
Figure 2ASC responses to TIV immunization in the young and elderly. (A) Frequency of TIV-specific IgA and IgG ASCs
Figure 3Concentration of total and TIV-specific IgA and IgG in PPAbs generated on day 7 or 8 after TIV immunization
Figure 5Avidity of vaccine-specific PPAbs from young and elderly TIV recipi-ents. The avidity of vaccine-specific PPAb is defined as the concentra-tion of TIV-specific PPAb (Figure 3B) divided by the TIV-specific ELISA titer of PPAb (Figure 1B) for each do
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