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Sepsis induced immune dysfunction: can immune therapies reduce mortality?

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Figure

Figure 1. Historical and current sepsis mortality distribution. (A) Historically, sepsis deaths have occurred in a biphasic distribution, with an initial early peak at several days due to inadequate resuscitation, resulting in cardiac and pulmonary failure
Figure 2. Immune dysregulation in sepsis. New insights into immune dysregulation have been gained using samples from deceased septic patients as well as from severely injured trauma patients
Table 1. Immune modulators and proposed benefits for sepsis therapy

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