O Mannosylation in Candida albicans Enables Development of Interkingdom Biofilm Communities

When it was spotted onto medium containing serum and 1.5% agar, hyphal growth did not emanate from the nce102 ⌬ mutant into the surrounding agar as it did for the wild-type

Given the importance of GPI-anchored proteins to cell wall formation and stability, we decided to examine the “integral cell wall” protein content and composition of the mutant

Compared to the wild type, SUN41 deletion strains exhibited a defect in biofilm formation, a reduced adherence on a Caco-2 cell monolayer, and were unable to form hyphae on solid

Candida albicans Hwp1, Hwp2, and Rbt1 are related cell wall proteins expressed during the programs of sexual differentiation and filamentous growthC. In this study, we compare

In con- trast, nearly all of the older sur7 ⌬ mutant cells showed altered calcofluor white staining of the outer cell wall and intracellular growth of the cell wall (Fig.. Time

In iron depleted medium at pH4.5, reduced growth of the NRG1 mutant relative to wild-type was observed, however growth was restored to wild-type levels or greater at pH

albicans cell wall mannosylation is a key determinant in the rate of engulfment; the absence of specific PAMPs in the glycosylation mutant strains delays engulfment once

albicans mutants deficient in production of Mnt1 and Mnt2 proteins are modified in cell wall structure (Munro et al. 2011), reduced in adherence levels to human buccal