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Nucleosome rotational setting is associated with transcriptional regulation in promoters of tissue specific human genes

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Figure

Figure 1 A 10-bp periodic signal is present downstream of human transcription start sites(base +1 is the first transcribed base)
Figure 2 CpG islands separate transcription start sites with and without the 10-bp RR periodic signal
Figure 3 The periodic signal varies with expression level and specificity, and H3K56 acetylationversus M shows that increased H3K56 acetylation levels is significantly correlated with increased 10-bp periodic signal (Wilcoxon rank sum test, one sided: L sh
Figure 4 Schematic representation of the spatial relationships between the nucleosome, the DNA molecule and RNA Pol II× 36° = 180° around the helical axis with respect to RNA pol II in order to preserve the contacts between the histones and the minor groov
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